Efficacy of Oral Sarolaner in Canine Demodicosis

Abstract

Dogs presented to small animal dermatology unit of Veterinary Clinical Complex, Rajendranagar with a comprehensive history of widespread itching, alopecia, thickened skin, skin discoloration, formation of scales and crusts with normal deworming and vaccination status were taken for the study. Clinical examination was carried out and dogs having signs of lichenified skin, alopecia, erythema, papules, comedones, as well as the presence of Demodex mite on skin scrapping were included in the study. these dogs were treated by randomly dividing them into two groups, viz., group I (n=28) treated with tab. ivermectin (400 mcg/kg, PO, SID) until two successive negative scrapings and group II (n=28) treated with tab. Sarolaner, an iso oxazoline-class parasiticide administered orally at a dosage of 2 mg/kg once a month. Mites were counted once in 15 days in both groups. Parasitological cure in group I was 60.71, 78.57 and 92.85 percent respectively, in subsequent months, whereas in group II 67.85 and 100 percent respectively, after the first and second month of therapy. Remarkably, the dogs of group II exhibited complete clinical recovery by the second month of treatment without any relapse. Additionally, all the dogs were also managed with chlorhexidine shampoo bath weekly once and immune-boosting syrup once a day.