Electrolyte, blood gas and acid-base imbalance in canine chronic renal disease in dogs


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Authors

  • Katyayini Sharma Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh
  • Ajay Katoch Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh
  • Ankur Sharma Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh
  • Devina Sharma Department of Veterinary Parasitology, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh
  • Adarsh Kumar Department of Veterinary Surgery and Radiology, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

https://doi.org/10.56093/ijvm.v45i1.168043

Keywords:

Chronic kidney disease, Acid-base, Electrolytes

Abstract

Chronic kidney disease (CKD) in dogs is a progressive and often irreversible condition where the kidneys gradually lose their ability to filter waste, regulate fluid balance and maintain essential electrolyte levels. Acid-base disturbances are commonly identified in critically ill veterinary patients. So, the present investigation was aimed to study blood gas, acid base and electrolyte alteration in canine chronic kidney disease. Study was conducted on 20 dogs suffering from stage IV chronic kidney disease out of which 10 cases were found to be positive for haemoprotozoan infection through microscopic examination or rapid diagnostic kits.  Haematologically mean values of TEC, PCV and Platelets were significantly reduced. Biochemically the mean values of Creatinine, SGPT and SGOT were significantly increased. Mean values of HCO3, pCO2, BE and BB were significantly decreased as compared to healthy dogs on venous blood gas and acid-base analysis. Electrolyte and mineral estimation revealed significant decrease in the values of sodium, chloride, calcium and magnesium whereas phosphorus were increased. The assessment of blood gas, acid-base balance, electrolyte levels and timely presentation of clinical cases played a crucial role in managing canine chronic kidney disease.

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Author Biographies

  • Katyayini Sharma, Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

    Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.

    M.VSc 

  • Ajay Katoch, Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

    Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.

    Assistant Professor

  • Ankur Sharma , Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

    Department of Veterinary Medicine, DGCN College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.

    Assistant Professor

  • Devina Sharma , Department of Veterinary Parasitology, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

    Department of Veterinary Parasitology, DGCN College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.

    Assistant Professor

  • Adarsh Kumar , Department of Veterinary Surgery and Radiology, DGCN College of Veterinary and Animal Sciences, Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh

    Department of Veterinary Surgery and Radiology, DGCN College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.

    Professor and Head

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Submitted

20-06-2025

Published

30-06-2025

How to Cite

Katyayini Sharma, Ajay Katoch, Ankur Sharma, Devina Sharma, & Adarsh Kumar. (2025). Electrolyte, blood gas and acid-base imbalance in canine chronic renal disease in dogs. Indian Journal of Veterinary Medicine, 45(1). https://doi.org/10.56093/ijvm.v45i1.168043
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