Clinical and molecular evaluation of Proteus mirabilis in a family pet dog with urolithiasis
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Authors
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T. Ranjith Vimalraj
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P. Selvaraj
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K. Senthilkumar
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P. Pothiappan
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S. Kavitha
Keywords:
Proteus mirabilis, dog, struvite crystals.Abstract
Urinary tract infections are a major concern in family pet dogs. Golden Retriever dog was found to have urinary incontinence, haematuria, stranguria and foul-smelling urine. Radiography and ultrasonography confirmed multiple nephroliths in the right kidney and urethral calculi measuring 5.28 mm. Elevated BUN, creatinine, phosphorus, anemia, haematuria, proteinuria, and struvite crystalluria were noticed. The isolation and characterization of Proteus mirabilis, using both conventional and molecular methods, including 16S rRNA gene sequencing, confirmed its association with urolithiasis. Urethral calculi were relieved by retrograde urohydropropulsion, and the dog was treated with Amoxicillin-Clavulanate along with dietary and supportive therapy. Post-treatment urinalysis by the fourth week showed no abnormalities, indicating clinical improvement.
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