Studies on the anti-inflammatory properties of Drymaria cordata leaf extract


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Authors

  • C C BARUA
  • A G BARUA
  • J D ROY
  • B BURAGOHAIN
  • P BORAH

Keywords:

Anti-inflammatory, Carrageenan, Drymaria cordata, Formalin, Methanolic

Abstract

The anti-inflammatory effects of Drymaria cordata methanolic extract (DCME) at the doses 300 to 900 mg/kg body wt. p.o was evaluated and compared with control and standard drug - Indomethacin (10 mg/kg body wt. p.o.). Carrageenaninduced paw oedema model in rats and mice, formalin-induced paw licking in mice were used for evaluation. Antiinflammatory effect of DCME was dose dependent and comparable with the standard drug- Indomethacin in carrageenan induced paw oedema in rat and mice. In formalin-induced paw licking model, there was significant reduction in duration of paw licking in early and late phase as well. Therefore, it can be concluded that DCME possesses anti-inflammatory property which could be due to presence of flavanoids, alkaloids and steroids.

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How to Cite

BARUA, C. C., BARUA, A. G., ROY, J. D., BURAGOHAIN, B., & BORAH, P. (2010). Studies on the anti-inflammatory properties of Drymaria cordata leaf extract. The Indian Journal of Animal Sciences, 80(12). Retrieved from https://epubs.icar.org.in/index.php/IJAnS/article/view/2199

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Articles