Cavernous splenic hemangiosarcoma in a dog - A pathological study

Abstract

A 12-year-old non-descript male dog was presented with a history of lethargy, vomiting, and loss of appetite. A complete blood count revealed elevated haematocrit, neutrophilia and thrombocytopenia. Abdominal ultrasonography revealed a mass at the splenic tail with a characteristic honeycomb appearance. Cytological examination showed large, pleomorphic, oval to spindle-shaped cells exhibiting nuclear hyperchromasia and a high nuclear-to-cytoplasmic ratio. Splenectomy was performed and the excised mass was subjected to histopathological evaluation. Histological examination revealed large cavernous vascular spaces lined by markedly pleomorphic and plump endothelial cells. Based on the histopathological features, a diagnosis of splenic hemangiosarcoma was made.