A small indigenous fish prescribed as a dietary supplement to control nocturnal enuresis
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Abstract
The medicinal and therapeutic value of fish is known for centuries and it is harnessed to cure and prevent a number of human diseases. Xenentodon
cancila is a small indigenous fish that is used in the folklore medicine for the nocturnal enuresis (bedwetting) in growing children. Nocturnal enuresis is a clinical condition in which involuntary urination takes place at night while asleep, after the age at which bladder control usually occurs. To investigate the nutritional factors that could possibly be contributing to such therapeutic
properties, we thoroughly studied the nutritional composition of Xenentodon cancila. Crude protein and crude fat contents were determined by Kjeldahl and Soxhlet methods, respectively. Amino acid, fatty acid and mineral analysis were carried out using HPLC, GC-MS and ICP-AES respectively. It was found that the fish is rich in protein (15%), functional amino acid leucine, essential amino acids isoleucine and valine and fatty acids like capric acid (10.05%) and myristic acid (9%) besides 12% unsaturated fatty acids. Mineral profiling of the fish showed that the fish is a very rich source of
phosphorous and copper; besides, it contains calcium, potassium, iron. The therapeutic property of Xenentodon cancila could be due to the synergistic effect of these micronutrients, especially the trace elements. However,
it merits further investigation as nocturnal enuresis has psychological and behavioral impacts on the growing children.
Keywords Therapeutics, Nocturnal enuresis, Xenontodon cancilla, Nutrient profiling
References
Alves RRN, Fauna used in popular medicine in North east Brazil. J Ethnobiol Ethnomed, 5 (2009) 1
Mohanty BP, Sudheesan D, Sankar TV, Das MK, Sharma AP, Therapeutic value of fish
http://urology.ucsf.edu/sites/urology.ucsf.edu/files/uploaded-files/
basic-page/nocturnal_enuresis_0.pdf
Glazener, CMA, Evans JHC (2002) Desmopressin for nocturnal enuresis in children. Cochrane Database Syst Rev. 3 (2002) CD002112
Fitzwater D, Macknin ML, Risk/bene?t ratio in enuresis therapy. Clinical Pediatrics 31(1992) 308-10
AOAC, Official Method of Analysis, Association of Official Analytical Chemists, Gaithersburg, Md, USA, 17th edition, 2000
Ishida Y, Fujita T, Asai K, "New detection and separation method for amino acids by high-performance liquid chromatography," Journal of Chromatography, 204, (1981) 143-148, 1981
Mohanty BP, Mahanty A, Ganguly S, Sankar TV, Chakrabarty K, Amino acid composition of 27 food fishes and their importance in clinical nutrition. J Amino Acids 2014 (2014) 269797
Sastry CSP, Tammuru K, Spectrophotometric determination of tryptophan in protein," Journal of Food Science and Technology, 22 (1985) 146-147
Folch J, Less M, Stanley GHS, A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957) 497-509
Metcalfe LD, Schmitz AA, Petha JR, Rapid preparation of fatty acid esters from lipids for gas chromatographic analysis. Anal Chem 38 (1966) 524-535
Cindric IJ, Krizman I, Zeiner M, Kampic S, Medunic G, Stingeder
G (2012) ICP-AES determination of minor and major elements in apples after microwave assisted digestion. Food Chem 135:2675-2680
Ahmed S, Arifur Rahman AFM, Ghulam Mustafa M, Belal Hossain M, Nahar N (2012) Nutrient Composition of Indigenous and Exotic Fishes of Rainfed Waterlogged Paddy Fields in Lakshmipur, Bangladesh. World Journal of Zoology 7 (2012) 135-140
Wille S, Aili M, Harris A, Aronson S (1994) Plasma and urinary levels of vasopressin in enuretic and nonenuretic children. Scand J Urol Nephrol 28(2):119-22
Eggert P, Kühn B, Antidiuretic hormone regulation in patients with primary nocturnal enuresis. Arch Dis Child. 73(6) (1995) 508-511
Canadian Paediatric Society (2005) Management of primary nocturnal enuresis. Paediatr Child Health 10(10) (2005) 611-614
Carvounis C P, Carvounis G, Wilk BJ, Importance of amino acids on vasopressin-stimulated water flow. J Clin Invest 76(2) (1985) 779-788
http://www.chemicalland21.com/industrialchem/organic/CAPRIC%20ACID.htm
Logan AC, Lesperance F, Primary nocturnal enuresis: omega-3 fatty acids may be of therapeutic value. Med Hypotheses 64(6) (2005) 1188-91
Mohanty BP, Mahanty, A, Ganguly, S, Mitra T, Karunakaran D, Anandan R (2018) Nutritional composition of food fishes and their importance in
providing food and nutritional security
Mohanty BP, Sankar TV, Ganguly S, Mahanty A, Anandan R, Chakrabarty K., et al. (2016). Micronutrient composition of 35 food fishes from India and their significance in human nutrition. Biological Trace Element Research, 174, 448-458
Audran M, Legrand E, Hypercalciuria. Joint Bone Spine 67(6) (2000) 509-15
h t t p : / / w w w. n l m . n i h . g o v / m e d l i n e p l u s / e n c y / a r t i c l e /002424.htm
Ghaddar S, Saoud IP (2012) Seasonal changes in phosphorus content of fish tissue as they relate to diets of renal patients. J Ren Nutr 22(1):67-71
Mahanty A, Ganguly S, Verma A, Sahu S, Mitra P, Paria P et al. Nutrient profile of small indigenous fish Puntius sophore:
proximate composition, amino acid, fatty acid and micronutrient profiles. Natl Acad Sci Lett 37 (2014)39-44
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