Nutrigenomics in Livestock Nutrition: A Pathway to Enhanced Animal Health and Productivity


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Authors

  • D. Chandaka Centurion University of Technology and Management
  • R.K. Swain
  • P. K. Regulagadda
  • U. Chandaka
  • H. Mekapothula
  • S. Salur

Keywords:

Nutrition, Genes, Livestock, Production, Health, Poultry

Abstract

Nutrigenomics represent emerging discipline that scrutinizes the intricate relationship between diet and genetic expression. These fields investigate how bioactive compounds in food influence gene expression and ultimately impact animal and human metabolism. In livestock, the study of nutrigenomics is constrained by high costs, long generational distances, and ethical considerations. Recent research in livestock nutrigenomics has primarily focused on elucidating the effects of dietary modifications on breeding efficiency, production traits, and animal health. By integrating disciplines such as nutrition, molecular biology, genomics, bioinformatics, molecular medicine, and epidemiology, nutrigenomics aims to elucidate the epigenetic mechanisms underlying disease occurrence. This review provides a comprehensive overview of nutrigenomics, highlighting its significance in understanding the interaction between diet and gene expression in livestock. By deciphering the intricate molecular pathways involved, nutrigenomics holds promise for personalized nutrition strategies tailored to individual genotypes, ultimately improving health outcomes for animals.

 

References

Anderson, P.T. 2000. Mechanisms by which metabolic modifiers alter growth rate and carcass composition of meat animals. In Recipr. Meat Conf (Vol. 53, pp. 31-35).

Asmelash, B., Mahlet, D. and Brhane, H. 2018. Livestock nutrigenomics applications and prospects. Journal of Veterinary Science and Technology. 9: 1-4.

Banerjee, G., Pal, R. and Ray, A.K. 2015. Applications of nutrigenomics in animal sectors: A review. Asian Journal of Animal and Veterinary Advances. 10(9): 489-499.

Bauman, D.E., Harvatine, K.J. and Lock, A.L. 2011. Nutrigenomics, rumen-derived bioactive fatty acids, and the regulation of milk fat synthesis. Annual review of nutrition. 3: 299-319.

Close, W.H. and Cole, D.J.A. 2001. Protein and amino acids. In: Nutrition of Sows and Boars. Nottingham University Press, UK. p. 71-96.

Dirinck, P., Winne, A.D., Frigg, M.C.M. 1996. Studies on vitamin E and meat quality. Effect of feeding high vitamin E levels on time-related pork quality. Journal of Agriculture and Food Chemistry. 44: 65-68.

Elolimy, A.A., Moisá, S.J., Brennan, K.M., Smith, A.C., Graugnard, D., Shike, D.W. and Loor, J.J. 2018. Skeletal muscle and liver gene expression profiles in finishing steers supplemented with Amaize. Animal Science Journal. 89(8): 1107-1119.

Fremaut D. 2003. Trace mineral proteinates in modern pig production: reducing mineral excretion without sacrificing performance. In: Nutritional Biotechnology in the Feed and Food Industries, Proceedings of Alltech’s 19th Annual Symposium (T.P. Lyons and K.A. Jacques, Eds.). Nottingham University Press, UK. 171-178.

German, J.B. 2005. Genetic dietetics: nutrigenomics and the future of dietetics practice.

Ghormade, V., Khare, A. and Baghel, R.P.S. 2011. Nutrigenomics and its applications in animal science. In Veterinary Research Forum, Faculty of Veterinary Medicine, Urmia University. 2(3): 147-155.

Gionbelli, T.R.S., Veloso, C.M., Rotta, P.P., Valadares Filho, S.C., C. Carvalho, B., Marcondes, M.I., S. Cunha, C., Novaes, M.A.S., Prezotto, L.D., Duarte, M.S. and Gionbelli, M.P. 2018. Foetal development of skeletal muscle in bovines as a function of maternal nutrition, foetal sex and gestational age. Journal of animal physiology and animal nutrition. 102(2): 545-556.

Harland, J.I. 2005. Nutrition and genetics: mapping individual health. ILSI, Europe.

Hiller, B., Herdmann, A. and Nuernberg, K. 2011. Dietary n-3 fatty acids significantly suppress lipogenesis in bovine muscle and adipose tissue: a functional genomics approach. Lipids. 46: 557-567.

Jacometo, C.B., Zhou, Z., Luchini, D., Corrêa, M.N. and Loor, J.J. 2017. Maternal supplementation with rumen-protected methionine increases prepartal plasma methionine concentration and alters hepatic mRNA abundance of 1-carbon, methionine, and transsulfuration pathways in neonatal Holstein calves. Journal of Dairy Science. 100(4): 3209-3219.

Jing, D. Y. and Defa, Li. 2009. Nutrigenomics Approach-A strategy for identification of nutrition responsive genes influencing meat edible quality traits in swine. Asian-Australasian journal of animal sciences, 22(4): 605-610.

Kocher, A. 2004. The potential for immunosaccharides to maximize growth performance. Interfacing immunity, gut health and performance.107-115.

Kore, K.B., Pathak, A.K. and Gadekar, Y.P. 2008. Nutrigenomics: emerging face of molecular nutrition to improve animal health and production. Veterinary World. 1(9): 285.

Lindemann, M.D., Carter, S.D., Chiba, L.I., Dove, C.R., LeMieux, F.M. and Southern, L.L. 2004. A regional evaluation of chromium tripicolinate supplementation of diets fed to reproducing sows. Journal of animal science. 82(10): 2972-2977.

Long, N.M., Tousley, C.B., Underwood, K.R., Paisley, S.I., Means, W.J., Hess, B.W., Du, M. and Ford, S.P. 2012. Effects of early- to mid-gestational undernutrition with or without protein supplementation on offspring growth, carcass characteristics, and adipocyte size in beef cattle. Journal of Animal Science. 90: 197–206.

Mahan, D., Zawadzki, J. and Guerrero, R. 2002. Mineral metabolism and boar fertility: observations from Latin American to Europe. In: Biotechnology in the Feed and Food Industries, Proceedings of Alltech’s 18th Annual Symposium (T.P. Lyons and K.A. Jacques, Eds.). Nottingham University Press, UK. p. 411-418.

Martin, D., Muriel, E., Gonzalez, E., Viguera, J. and Ruiz, J. 2008. Effect of dietary conjugated linoleic acid and monounsaturated fatty acids on productive, carcass and meat quality traits of pigs. Livestock Science. 117(2-3): 155-164.

Miggiano, G.A. and De Sanctis, R. 2006. Nutritional genomics: toward a personalized diet. La Clinica Terapeutica. 157(4): 355-361.

Mohrhauser, D.A., Taylor, A.R., Underwood, K.R., Pritchard, R.H., Wertz-Lutz, A.E. and Blair, A.D. 2015. The influence of maternal energy status during midgestation on beef offspring carcass characteristics and meat quality. Journal of animal science. 93(2): 786-793.

Nowacka-Woszuk, J. 2020. Nutrigenomics in livestock—recent advances. Journal of Applied Genetics. 61(1): 93-103.

Rao, L., Prolla, T.A. and Puschner, B. 2001. Gene expression profiling of low selenium status in the mouse intestine: transcriptional activation of genes linked to DNA damage, cell cycle control and oxidative stress. The Journal of nutrition. 131(12): 3175-3181.

Rauw, W.M., Rydhmer, L., Kyriazakis, I., Øverland, M., Gilbert, H., Dekkers, J.C., et al. 2020. Prospects for sustainability of pig production in relation to climate change and novel feed resources. Journal of the Science of Food and Agriculture. 100(9): 3575–3586.

Sabino, M., Carmelo, V.A.O., Mazzoni, G., Cappelli, K., Capomaccio, S., Ajmone-Marsan, P., Verini-Supplizi, A., Trabalza-Marinucci, M. and Kadarmideen, H.N. 2018. Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils. BMC genomics. 19: 1-15.

Susmitha, T. and Sagar, L.V. 2023. Nutrigenomics: An emerging tool in Nutrition.

Teixeira, P.D., Oliveira, D.M., Chizzotti, M.L., Chalfun-Junior, A., Coelho, T.C., Gionbelli, M., Paiva, L.V., Carvalho, J.R.R. and Ladeira, M.M. 2017. Subspecies and diet affect the expression of genes involved in lipid metabolism and chemical composition of muscle in beef cattle. Meat Science. 133: 110-118.

ul Haq, Z., Saleem, A., Khan, A.A., Dar, M.A., Ganaie, A.M., Beigh, Y.A., Hamadani, H. and Ahmad, S.M. 2022. Nutrigenomics in livestock sector and its human-animal interface-a review. Veterinary and Animal Science. 17: 100262.

Yan, X., Zhu, M.J., Dodson, M.V. and Du, M. 2013. Developmental programming of fetal skeletal muscle and adipose tissue development. Journal of

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Submitted

18-03-2024

Published

25-09-2024

Issue

Vol. 41 No. 2 (2024)

Section

Review

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Copyright remains with the society and author jointly. However, material can be used for research, teaching and to achieve goals of the society.

How to Cite

, D. C., R.K. Swain, P. K. Regulagadda, U. Chandaka, H. Mekapothula, & S. Salur. (2024). Nutrigenomics in Livestock Nutrition: A Pathway to Enhanced Animal Health and Productivity. Indian Journal of Animal Nutrition, 41(2). https://epubs.icar.org.in/index.php/IJAN/article/view/149760