Cumin (Cuminum cyminum L.) an export-oriented Indian seed spice with inherent nutraceutical and therapeutic attributes: A review
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Authors
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S.S. Meena
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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Y.K. Sharma
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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M.K. Mahatma
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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S. Lal
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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M.D. Meena
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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R.D. Meena
ICAR-National Research Centre on Seed Spices, Ajmer, Rajasthan, India
Author
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N. Chaudhary
Author
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Ravi Y
Author
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V. Bhardwaj
Author
Keywords:
Essential oil, flavorant, volatile oil, phytochemicals, scavenging activityAbstract
Cumin seeds and value-added products are used in beverages, liquors,
candy, nutraceuticals, therapeutics, toiletries, perfumery and lotions. In the
Indian systems of medicine, cumin finds a vital role through its essential &
total oil components and various aqueous and alcoholic extracts. Cumin
seeds contain volatile oil (3–4%), the primary active principles of which are
cumin aldehyde, terpenes (45–50%), phenols, unsaturated and saturated
fatty acids, etc., those occur in varying fractions compensating each other,
which act as a scavenger for free radicals and antioxidants. As a
nutraceutical, cumin seeds contain plenty of iron, magnesium, calcium,
manganese, and phosphorus. The vitamins present include thiamine,
riboflavin, niacin, vitamin A, C, E, K, and vitamin B6. The seedspossess
diuretic, carminative, stimulant, digestive, tonic, appetizer, stomachic and
astringent properties. It is traditionally an essential critical remedial agent
for digestion, diarrhoea, leucorrhoea, eczema, atonic, flatulence,
dyspepsia and abdominal pains. Phytochemicals like alkaloid, coumarin,
anthraquinone, flavonoid, protein, glycoside, resin, saponin, tannin and
steroids are abundant in its seed. Cumin seed extracts bear various
medicinal properties such as insecticidal, antimicrobial, anti-inflammatory,
antioxidant, antidiabetic, anticancer, hypotensive, bronchodilator,
immunological, contraceptive, aldose reductase, analgesic,alpha-
glucosidase and tyrosinase inhibitory effects, etc. Thus use of cumin offers
combined advantages, providing both nutraceutical and therapeutic
properties simultaneously.
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References
1. Anonymous, 2022. www.http//:indianspices.com
2. Al-Batania, B.A., Maslat, A.O. and Al-Kofahi, M.M. 2003.
3. Element analysis and biological studies on ten
4. oriental spices using XRF and Ames test. J Trace
5. Elem Med Biol., 17(2):85–90.
6. Atrooz, O.M. 2013. The Effects of Cuminum cyminum L.
7. and Carumcarvi L. seed extracts on human
8. erythrocyte hemolysis. Int. J Biol., 5(2):57-63.
9. Azez, S. 2008. Chemistry of Spices, CABI, pp. 211-226.
10. Bhat, S.P., Rizvi, W. and Kumar, A. 2014. Effect of
11. Cuminum cyminum L. seed extracts on pain and
12. inflammation. J Nat Remedies, 14(2):186-192.
13. Borges, P. and Pino, J. 1993. The isolation of volatile oil
14. from cumin seeds by steam distillation. Mol Nutr
15. Food Res., 37(2):123–26.
16. Boskabady, M.H., Kiani, S. and Azizi, H. 2005. Relaxant
17. effect of Cuminum cyminum on guinea pig
18. tracheal chains and its possible mechanism(s).
19. Indian J Pharmacol, 37(2):111-115.
20. Chaudhary, N., Husain, S.S. and Ali, M. 2014. Chemical
21. composition and antimicrobial activity of cumin oil
22. (Cuminumcyminum, Apiaceae). J Pharm Pharm
23. Sci., 3(7):1428-1441.
24. Chauhan, P.S., Satti, N.K., Suri, K.A., Amina, M.and
25. Bani, S. 2010.Stimulatory effects of Cuminum
26. c y m i n u m a n d f l avo n o i d g l y c o s i d e o n
27. cyclosporine-A and restraint stress induced
28. immune-suppression in Swiss albino mice.Chem-
29. Biol Interact.,185(1):66-72.
30. Derakhshan, S., Sattari and Bigedli, M. 2007.Evaluation
31. of antibacterial activity and biofilm formation in
32. Klebsiellapneumoniae in contact with essential oil
33. and alcoholic extract of cumin seed (Cuminum
34. th
35. cyminumL.). 17 EuropeanCongress of Clinical
36. Microbiology and Infectious Diseases ICC,
37. Munich, Germany, 31 Mar.-04 Apr., 2007.
38. Dhandapani, S., Subramanian, V., Rajagopal, S. and
39. Namasivayam, N. 2002.Hypolipidemic effect of
40. CuminumcyminumL. on alloxan-induced diabetic
41. rats, Pharmacol Res., 46(3):251-255.
42. Dubey, P.N., Saxena, S.N., Mishra, B.K., Solanki, R.K.,
43. Vishal, M.K., Singh, B., Sharma, L.K., John, S.,
44. Agarwal, D. and Yogi, A. 2017.Preponderance of
45. cumin (Cuminum cyminum L) essential oil
46. constituents across cumin growing agro-
47. ecological sub regions, India. J Ind Crops Prod.,
48. :50-59.
49. Dubey, P.N., Saxena, S.N., Mishra, B.K. and Aishwath,
50. O.P. 2016. Assessment of variability in physical
51. and chemical composition of Cuminum cyminum
52. seeds from arid and semiarid India. Indian J Agric
53. Sci.,10:1366-1370.
54. Elhabib, E.M.,Homeida, M.M.A. and Adam, S.E.I. 2007.
55. Effect of combined paracetamol and Cuminum
56. cyminum or Nigella sativa used in Wistar Rats. J
57. Pharmacol Toxicol., 2 (7):653-659.
58. Farrell, K.T. 1985. In: Spices, Condiments and
59. Seasonings. The AVI Publishing Co.Inc.Westport,
60. Connecticut: 98–100.
61. Gagandeep, Dhanalakshmi, S., Mendiz, E., Rao, A.R.
62. and Kale, R.K. 2003. Chemopeventive effects of
63. Cuminum cyminum in chemically induced for
64. stomach and uterin complex cervix tumours in
65. mu r i n e m o d e l s y s t e m s . N u t r C a n c e r. ,
66. (2):171–180.
67. Gohari, A.R. and Saeidnia, S.A. 2011.Review on
68. phytochemistry of Cuminum cyminum seeds and
69. its standards from field to market. Pharmacogn J.,
70. (25):1-5.
71. Haghparast, A., Shams, J., Khatibi, A., Alizadeh,
72. A.M.and Kamalinejad, M. 2008. Effects of the fruit
73. essential oil of Cuminum cyminum Linn
74. (Apiaceae) on acquisition and expression of
75. morphine tolerance and dependence in mice.
76. Neurosci Lett., 440(2):134-139.
77. Hashum, F. and Al-Hashemi, Y. 2014. Chromatographic
78. separation and identification of some volatile oils,
79. organic acids and phenols from the seeds of
80. Cuminum cyminum growing in Iraq. Int J Recent
81. Res Appl Stud.,19 (1):80-90.
82. Iacobellis, N.S., Cantore, P.L.,Capasso, F. and Senatore,
83. F. 2005. Antibacterial activity of Cuminun cyminum
84. L. and Carumcarvi L. essential oils. J Agric Food
85. Chem., 53(1):57–61.
86. Janahmadi, M., Niazi, F., Danyali, S.and Kamalinejad, M.
87. Effects of the fruit essential oil of Cuminum
88. cyminum Linn (Apiaceae) on pentylenetetrazol-induced epileptiform activity in F1 neurones of
89. Helix aspersa.J Ethno Pharma Col., 104(1-
90. :278-282.
91. Joerg, G., Thomas, B. and Christof, J. 2000. PDR for
92. Herbal Medicines. Medical Economics Company,
93. Inc. at Montvale. 237-238.
94. Kalaivani, P., Saranya, R.B., Ramakrishnan, G., Ranju,
95. V., Sathiya, S., Gayathri, V., Thiyagarajan,
96. L.K.,Venkhatesh, J.R., Babu, C.S. and
97. Thanikachalam, S. 2013.Cuminum cyminum, a
98. dietary spice, attenuates hypertension via
99. endothelial nitric oxide synthase and NO pathway
100. in renovascular hypertensive rats. Clin Exp
101. Hypertens., 35(7):534-542.
102. Karnick, C.R. 1991. Aclinical trial of a composite herbal
103. drug in the treatment of diabetes mellitus.
104. Aryavaidyan, 5:36–46.
105. Kivanc, M., Akgul, A. and Dogan, A. 1991. Inhibitory and
106. stimulatory effects of cumin, oregano and their
107. essential oils on growth and acid production of
108. Lactobacillus planatarum and Leuconstoc
109. mesenteroides. Int J Food Microbiol.,
110. (1):81–85.
111. Koppula, S. and Choi, D.K. 2011. Cuminum cyminum
112. extract attenuates scopolamine-induced memory
113. loss and stress-induced urinary biochemical
114. changes in rats: a noninvasive biochemical
115. approach. Pharm Biol., 49(7):702-708.
116. Krishnakantha, T.P. and Lokesh, B.R. 1993.
117. Scanvenging of superoxide anions by spice
118. principles. Indian J Biochem Biophys., 30(2):133–
119. Kubo, I. and Kinst-Hori, I. 1998. Tyrosinase inhibitors
120. f r o m c u m i n . J A g r i c F o o d C h e m . ,
121. (12):5338–5341.
122. Kumar, A., Singh, J.K., Ali, M., Kumar, R., Kumar, A.,
123. Nath, A., Roy, A.K., Roy, S.P. and Singh, J.K.
124. Evaluation of Cuminum cyminum L. and
125. Coriandrum sativum L. on profenofos induced
126. nephrotoxicity in swiss albino mice. Elixir Appl
127. Botany, 39: 4771-4773.
128. Lal,G., and Meena, S.S. 2018. Medicinal and therapeutic
129. potential of seed spices. Biomed J Sci Tech Res.,
130. (4):1-21.
131. Lee, H.S. 2005. Cuminaldehyde: aldose reductase and
132. alpha-glucosidase inhibitor derived from
133. Cuminum cyminum L seeds. J Agric Food Chem.,
134. (7):2446-2450.Leung, A.Y. 1980. Encyclopedia of Common Natural
135. Ingredients used in Foods, Drugs and Cosmetics,
136. John Wiley, Hoboken, NJ.
137. Meena, R.D., Baranwal, V.K., Lal, G., Sharma, Y.K.,
138. Meena, S.S. and Meena, N.K. 2022. First report of
139. Vanillla distortion mosaic virus on cumin
140. (Cuminum cyminum) in India. J Plant Pathol,
141. https://doi.org/10.1007/s42161-022-01077-3.
142. Meena, S.S., Lal, G. and Lal,S.. 2020. A medicinal and
143. therapeutic property of seed spices. published by
144. director, NRCSS, Ajmer, Page-1-44
145. Merah, O., Sayed-Ahmad, B., Talou, T., Saad, Z., Cerny,
146. M., Grivot, S., Evon, P. and Hijazi, A. 2020.
147. Biochemical composition of cumin seeds, and
148. biorefining study. Biomol., 10:1054
149. Moawad,, S.A., El-Ghorab, A.H., Hassan, M., Nour-
150. Eldin, H. and El-Gharabli, M.M. 2015. Chemical
151. and microbiological characterization of Egyptian
152. cultivars for some spices and herbs commonly
153. exported abroad. Food Nutri Sci., 6(7):643-659.
154. Morshedi, D,, Aliakbari, F., Tayaranian-Marvian, A.,
155. Fassihi, A., Pan-Montojo and Fand Pérez –
156. Sánchez, H. 2015. Cumin aldehyde as the major
157. component of Cuminum cyminum, a natural
158. aldehyde with inhibitory effect on alpha-synuclein
159. fibrillation and cytotoxicity. J Food Sci., 80(10):
160. H2336-2345.
161. Morshedi,D., Kesejini,T.S., F.R.M., Marvian, A.T.,
162. Khalifeh, M. and Soroosh, M. 2014. Identification
163. and characterization of a compound from
164. Cuminum cyminum essential oil with antifibrilation
165. and cytotoxic effect. Res Pharma Sci., 9(6):431-
166. Parashar,M., Jakhar, M.L. and Malik, C.P. 2014. A review
167. on biotechnology, genetic diversity in cumin
168. (Cuminum cyminum). Life Sci., 4(4):L17-L34.
169. Parthasarathy, V.A., Chempakam, B. and Zachariah, T.J.
170. Chemistry of Spices. CAB Int., 211-226.
171. Prajapati, N.D., Purohit, S.S., Sharma, A.K. and Kumar,
172. T. 2003. A Hand Book of Medicinal Plant: A
173. Complete Source Book. Agrobios (India), Pp.1-
174. Pratyusha, A.C., Manmohan, B., Raju, S., Bhanuprasad,
175. T., Sruthi, V.V. and Kishore, R.N. 2013.
176. Comparative study of anti ulcer activity of aqueous
177. extracts of leaves of Piper betel Linn and dried
178. fruits of Cuminum cyminum Linn and their
179. combination in rats. Int J Adv Res.,1(4):192-195
180. Rai, N., Yadav, S., Verma, A.K., Tiwari, L. and Sharma,
181. R.K. 2012. A monographic profile on quality
182. specifications for a herbal drug and spice of
183. commerce- Cuminum cyminum L. Int. J Adv Herb
184. Sci Techno., 1(1):1-12.
185. Romagnol, C., Andreotti, E., Maietti, S., Rai, M. and
186. Mares, D. 2010. Antifungal activity of essential oil
187. from fruits of Indian Cuminum cyminum. Pharma
188. Biol. 48(7):834-838.
189. Roman-Ramos, R., Flores-Saenz, J. and Alarcon-
190. Aguilar, F.J. 1995. Antihyperglycaemic effect of
191. some edible plants. J Ethnopharmacol.,
192. (1):251-255.
193. Sahoo, H.B., Sahoo, S.K., Sarangi, S.P., Sagar, R.and
194. Kori, M.L. 2014.Anti-diarrhoeal investigation from
195. aqueous extract of Cuminum cyminum Linn seed
196. in albino rats. Pharmacogn Res.,6(3):204-209.
197. Sakhaee, E., Emadi, L., Azari, O., Kheirandish, R.,
198. EsmailiNejad, M.R.and Shafiei, B.H. 2015.Effects
199. of Cuminum cyminum L. essential oil on some
200. epididymal sperm parameters and histopathology
201. of testes following experimentally induced copper
202. poisoning in mice. Andrologia, 48(5):542-547.
203. Sambaiah, K. and Srinivasan, K. 1991. Effect of cumin,
204. cinnamon, ginger, mustard and tamarind in
205. induced hypercholesterolemic rats. Die Nahrung,
206. (1):47–51.
207. Satyanarayana, S., Sushruta, K., Sarma, G.S., Srinivas,
208. N. and Subba Raju, G.V. 2004. Antioxidant activity
209. of the aqueous extracts of spicy food
210. additives–evaluation and comparison with
211. ascorbic acid in vitro systems. J Herb
212. Pharmacother., 4(2):1-10.
213. Saxena, P., Gupta, R.and Gupta, R.S. 2015.
214. Contraceptive studies of isolated fractions of
215. Cuminum cyminum in male albino rats. Nat Prod
216. Res., 29(24):2328-2331.
217. Sayyah, M., Peirovi, A. and Kamalinejad, M. 2002. Anti-
218. nociceptive effect of the fruit essential oil of
219. Cuminum cyminum L. in rat. Iranian Biomed J,
220. (4):141-145.
221. Shaath, N.A. and Azzo, N.R. 1993. Essential oil of Egypt.
222. In: G. Charalambous(Ed.): Food FlavorIngredients
223. and Composition Charalambous, G, Ed., Elsevier,
224. Amsterdam pp. 591–603.
225. Shirke, S.S. and Jagtap, A.G. 2009. Effects of methanolic
226. extract of Cuminum cyminum on total serum
227. cholesterol in ovariectomized rats. Ind J
228. Pharmacol., 41(2):91-93.
229. Shirke, S.S., Jadhav, S.R. and Jagtap, A.G.
230. Methanolic extract of Cuminum cyminum
231. inhibits ovariectomy-induced bone loss in rats.
232. Exp Biol Med., 233(11):1403-1410.
233. Shivakumar, S.I., Shahapurkar, A.A., Kalmath, K.V. and
234. Shivakumar, B. 2010. Antiinflammatory activity of
235. fruits of Cuminum cyminum L. Der Pharma Lett.,
236. (1):22–24.
237. Srivastava, K.C. 1989.Extracts from two frequently
238. consumed spices cumin(Cuminum cyminum L.)
239. and turmeric (Curcuma longa) inhibit platelet
240. aggregation and alter eicosanoid biosynthesis in
241. human blood platelets. Prostaglandins Leuko
242. Essent Fat Acids, 37:57–64.3
243. Tomy, M.J., Dileep, K.V., Prasanth, S., Preethidan, D.S.,
244. Sadasivan, C. and Cuminaldehyde as a
245. lipoxygenase inhibitor: in vitro and in silico
246. validation. App Biochem Biotechnol.,174(1):388-
247. Wanner, J., Bail, S., Jirovetz, L., Buchbauer, G., Schmidt,
248. E., Gochev, V., Girova, T., Atanasova, T. and
249. Stoyanova, A. 2010. Chemical composition and
250. antimicrobial activity of cumin oil (Cuminum
251. cyminum). Nat Prod Commun., 5(9): 1355-1358.
252. Willatgamuwa, S.A., Platell, K., Saraswathi, G. and
253. Srinivasan, K. 1998. Antidiabetic influence of
254. dietary cumin seeds (Cuminum cyminum) in
255. streptozotocin induced diabetic rats. Nutr Res.,
256. (1):131–42.
257. Zare, R., Heshmati, F., Fallahzadeh, H.and
258. Nadjarzadeh, A. 2014.Effect of cumin powder on
259. body composition and lipid profile in overweight
260. and obese women. Complement Ther Clin Practi,
261. (4): 297-301.
262. Zohary, D. and Hopf, M. 2000. Domestication of Plants in
263. the Old World, third edition. Oxford University
264. Press, 206.
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