Coagulation Profile and D-dimer in Labrador Puppies with Parvo Viral Enteritis
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Keywords:
Parvo viral Enteritis - Prothrombin Time - aPTT - D-DimerAbstract
Management of puppies with parvo viral enteritis is a major challenge. Complicating factors include sepsis and coagulation status. In a study of PCR confirmed parvo affected labrador puppies, a hypercoagulable status was observed. Haematobiochemical examination revealed decreased hemoglobin, Packed Cell Volume and total erythrocyte count, hypoproteinaemia and hypoalbuminemia. The Activated Partial Thromboplastin Time (aPTT) was markedly prolonged. D – Dimer status was negative and was unremarkable.
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Dongre,J., Mehta, H.K. and Maheshwari, P. 2014. Serum Biochemical Observations in Dogs Affected with Canine Parvo Virus Infection. Indian Vet. J., 91: 96 – 97.
Ford, R.B. and Mazzaferro, E. 2006. Kirk and Bistner's Handbook of Veterinary Procedures and Emergency Treatment 8th Edn. Saunders, St. Louis, Missouri, pp:578.
Lopez, S.T.A., Emanuelli, M.P., Schmidt, C., Raiser, A.G., Mazzanti, A. and Alves, A.S. 2005. Reference ranges of prothrombin time (PT) and activated partial thromboplastin time (aPTT) in dogs. Cienc. Rural., 35: 381-384.
O'Sullivan, G., Durham, P.J.K., Smith, J.R. and Campbell, R.S.F. 1984. Experimentally induced severe canine parvoviral enteritis. Aust. Vet. J., 61: 1-4.
Otto, C.M, Rieser, T.M., Brooks, M.B. and Russell, M.W. 2000. Evidence of hypercoagulability in dogs with parvoviral enteritis. J. Am. Vet. Med. Assoc., 217: 1500-1504.
Pereira, C.A, Monezi, T.A., Mehnert, D.U., D’Angelo, M. and Durigon, E.L. 2000. Molecular characterization of canine parvovirus in Brazil by PCR. Vet. Microbiol., 75: 127–33.
Pogieterl, L.N.D., Jones, J.B., Patton, S.C. and Webb-Martin, T.A. 1981. Experimental parvovirus infection in dogs. Can. J. Comp. Med. Vet. Sci., 45: 212-216.
Salem, N.Y. 2014. Canine Viral Diarrhea: Clinical, Hematologic and Biochemical Alterations with Particular Reference to In-Clinic Rapid Diagnosis. Glob. Vet., 13: 302-307.
Vlasin, M., Rauser, R., Fichtel, T. and Novotny, J. 2004. Disseminated intravascular coagulopathy of the Dog. Acta Vet. Brno., 73: 497-505
Woods, C.B., Pollock, R.V.H. and Carmichael, L.E. 1980. Canine parvoviral enteritis. J. Am. Anim. Hosp. Assoc., 16: 171-179.