Coagulation Profile and D-dimer in Labrador Puppies with Parvo Viral Enteritis


78 / 72

Authors

  • Palanivelrajan M Associate Professor, Department of Veterinary Medicine, Veterinary College and Research Institute, Udumalpet - 642205
  • D. Sumathi Professor, Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Namakkal – 600 007
  • S. Ramesh Professor and Head (Retd.), Central Clinical Laboratory, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai – 600 007
  • P. Selvaraj Professor and Head, Veterinary Peripheral Hospital, Tamil Nadu Veterinary and Animal Sciences University, Chennai – 600 051

https://doi.org/10.56093/ijvm.v45i1.165631

Keywords:

Parvo viral Enteritis - Prothrombin Time - aPTT - D-Dimer

Abstract

Management of puppies with parvo viral enteritis is a major challenge. Complicating factors include sepsis and coagulation status. In a study of PCR confirmed parvo affected labrador puppies, a hypercoagulable status was observed. Haematobiochemical examination revealed decreased hemoglobin, Packed Cell Volume and total erythrocyte count, hypoproteinaemia and hypoalbuminemia. The Activated Partial Thromboplastin Time (aPTT) was markedly prolonged. D – Dimer status was negative and was unremarkable.

Downloads

Download data is not yet available.

References

Dongre,J., Mehta, H.K. and Maheshwari, P. 2014. Serum Biochemical Observations in Dogs Affected with Canine Parvo Virus Infection. Indian Vet. J., 91: 96 – 97.

Ford, R.B. and Mazzaferro, E. 2006. Kirk and Bistner's Handbook of Veterinary Procedures and Emergency Treatment 8th Edn. Saunders, St. Louis, Missouri, pp:578.

Lopez, S.T.A., Emanuelli, M.P., Schmidt, C., Raiser, A.G., Mazzanti, A. and Alves, A.S. 2005. Reference ranges of prothrombin time (PT) and activated partial thromboplastin time (aPTT) in dogs. Cienc. Rural., 35: 381-384.

O'Sullivan, G., Durham, P.J.K., Smith, J.R. and Campbell, R.S.F. 1984. Experimentally induced severe canine parvoviral enteritis. Aust. Vet. J., 61: 1-4.

Otto, C.M, Rieser, T.M., Brooks, M.B. and Russell, M.W. 2000. Evidence of hypercoagulability in dogs with parvoviral enteritis. J. Am. Vet. Med. Assoc., 217: 1500-1504.

Pereira, C.A, Monezi, T.A., Mehnert, D.U., D’Angelo, M. and Durigon, E.L. 2000. Molecular characterization of canine parvovirus in Brazil by PCR. Vet. Microbiol., 75: 127–33.

Pogieterl, L.N.D., Jones, J.B., Patton, S.C. and Webb-Martin, T.A. 1981. Experimental parvovirus infection in dogs. Can. J. Comp. Med. Vet. Sci., 45: 212-216.

Salem, N.Y. 2014. Canine Viral Diarrhea: Clinical, Hematologic and Biochemical Alterations with Particular Reference to In-Clinic Rapid Diagnosis. Glob. Vet., 13: 302-307.

Vlasin, M., Rauser, R., Fichtel, T. and Novotny, J. 2004. Disseminated intravascular coagulopathy of the Dog. Acta Vet. Brno., 73: 497-505

Woods, C.B., Pollock, R.V.H. and Carmichael, L.E. 1980. Canine parvoviral enteritis. J. Am. Anim. Hosp. Assoc., 16: 171-179.

Downloads

Submitted

05-03-2025

Published

01-07-2025

How to Cite

M, P., D. Sumathi, S. Ramesh, & P. Selvaraj. (2025). Coagulation Profile and D-dimer in Labrador Puppies with Parvo Viral Enteritis. Indian Journal of Veterinary Medicine, 45(1). https://doi.org/10.56093/ijvm.v45i1.165631
Citation