Intravenous Lipid Therapy in the Management of Ivermectin Toxicity in a Cat


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Authors

  • Mohanambal K Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal – 600 002
  • Sibhi, P Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal – 600 002
  • Sumathi, D., Ravi, R., Sasikala, K. and Ponnu Swamy, K. K. Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal – 600 002

https://doi.org/10.56093/ijvm.v45i1.168242

Keywords:

Ivermectin toxicity, kitten, lipid emulsion

Abstract

A 6-month-old female domestic short-haired kitten weighing about 1 kg was presented to Veterinary College and Research Institute, Namakkal with ataxia and lateral recumbency for 10 hours following accidental ingestion of a 10 mg over-the-counter ivermectin tablet. Mydriasis, absence of menace response, sluggish pupillary reflexes, tachycardia and dyspnoea were noticed. Ivermectin toxicity was diagnosed based on history and clinical findings. Treatment involved intravenous administration of lipid with normal saline. Significant clinical improvement was noted within 24 hours and by the third day, the kitten showed complete recovery.

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Author Biography

  • Mohanambal K, Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, Namakkal – 600 002

    Assistant Professor

    Department of Veterinary Clinical Medicine

    VCRI, Namakkal

References

Jourdan, G., Boyer, G., Raymond‐Letron, I., Bouhsira, E., Bedel, B. and Verwaerde, P. 2015. Intravenous lipid emulsion therapy in 20 cats accidentally overdosed with ivermectin. J. Vet. Emerg. Crit. Care., 25(5): 667-671.

Gonzalez Canga, A., Sahagun Prieto, A. M., Diez Liebana, M. J., Martinez, N. F., Vega, M. S, and Vieitez, J. J. 2009. The pharmacokinetics and metabolism of ivermectin in domestic animal species. Vet J., 179(1): 25–37. doi:10.1016/j.tvjl.2007.07.011.

Muhammad, S., Saqib, M. and Ahmad, M. 2004. Use of Neostigmine in Massive Ivermectin Toxicity in Cats. Vet. Hum. Toxicol., 46(3): 132–134.

Siroka Z and Svobodova Z. 2013. The toxicity and adverse effects of selected drugs in animals – overview. Pol. J. Vet. Sci., 16(1): 181–194.

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Submitted

26-06-2025

Published

01-07-2025

How to Cite

Mohanambal K, Sibhi, P, & Sumathi, D., Ravi, R., Sasikala, K. and Ponnu Swamy, K. K. (2025). Intravenous Lipid Therapy in the Management of Ivermectin Toxicity in a Cat. Indian Journal of Veterinary Medicine, 45(1). https://doi.org/10.56093/ijvm.v45i1.168242
Citation