Porcine skin graft for management of cutaneous wounds in dogs
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Authors
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Ravindra Jayavant Zende
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Vilas Mahadeo Vaidya
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Rupesh Nagesh Waghmare
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Vinay Suresh Lande
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Rajpal Sheshrao Khillare
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Suren Madhav Tambe
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Nidhi Sudhakaran Panicker
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Aishwarya Sivaraman Nair
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
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Aparna Hrushikesh Shirke
Maharashtra Animal and Fishery Sciences University, Nagpur - 440 001 (Maharashtra)
Keywords:
Cutaneous wound, Dog, Porcine skin graftAbstract
Porcine skin has the potential to serve as a biocompatible dressing due to its structural similarities. This study standardized the processing of porcine skin grafts for use as biological bandages and evaluated their clinical efficacy in adult dogs with open cutaneous wounds, alongside optimized the preservation techniques to determine their viability. Grafts of varying sizes were prepared and stored under different conditions to assess viability. Clinical evaluation included wound contraction, histopathology, and immunological response, with outcomes compared to conventional bandaging. Preservation in PBS with 15% glycerol at < 18°C extended graft viability up to 24 days. Dogs treated with porcine skin grafts exhibited faster wound healing, with significant improvement observed as early as 12th day post-application, as compared to 48th day in control group. Histopathological findings supported enhanced tissue regeneration with minimal adverse immune reactions. The study concluded that porcine skin grafts are a suitable, therapeutic and economical alternative for open wound management in dogs.
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References
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