Extraction and Functional Group Analysis of Gossypol from Cottonseed Meal


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Authors

  • MANOJ KUMAR Scientist, ICAR - Central Institute for Research on Cotton Technology (CIRCOT), Mumbai-400019
  • JAYASHREE POTKULE Junior Research Fellow, ICAR - Central Institute for Research on Cotton Technology (CIRCOT), Mumbai-400019
  • SUJATA SAXENA Principal Scientist, ICAR - Central Institute for Research on Cotton Technology (CIRCOT), Mumbai-400019

Keywords:

Gossypol, Extraction, FTIR, Cottonseed meal

Abstract

Gossypol is a polyphenolic aldehydic compound which has been studied for its versatile biological activities. The extraction of gossypol from cottonseed meal was attempted using acidified solvent system. Mixture of acetone: ethanol and water (70:20:10) at 4.5 pH with solid-to-liquid ratio of 1:20 can be considered as best conditions for the extraction of gossypol. The purity and presence of specific functional groups was confirmed using Fourier Transform Infrared (FTIR) spectroscopy. Study will give a basis to further optimize the protocol for efficient extraction of gossypol form cottonseed meal for possible applications in agriculture, medicine and pharmaceuticals.

References

Bellamy, L. J. (1975) - The Infrared Spectra of Complex Molecules (3rd Ed.), Chapman & Hall, London, pp.151–177.

Coutinho, E. M. (2002) - Gossypol: a contraceptive for men - Contraception, 65(4):259–263.

Dechary, J. M., Kupperman, R. P., Thurber, F. H., Altschul, A. M. and Loboratory, R. R. (1952) - Removal of gossypol from cottonseed by solvent extraction procedures - J. Am. Oil Chem. Soc., 29:339–341.

Gadelha, I. C., Fonseca, N. B., Oloris, S. C., Melo, M. M. and Soto-Blanco, B. (2014) - Gossypol toxicity from cottonseed products- Sci. World J., 231635.

Keshmiri-Neghab, H. and Goliaei, B. (2013) - Therapeutic potential of gossypol: An overview - Pharm.l Biol., 52(1):124–128.

Kuk, M. S., Tetlow, R. and Dowd, M. K. (2005)- Cottonseed extraction with mixtures of acetone and hexane - J. Am. Oil Chem. Soc., 82(8):609-612.

Kumar, M., Mageshwaran, V., Saxena, S., D’ Souza, C., Ashtaputre N., Patil S., Mahapatra A., Patil P. G. and Tak, Y. (2019) - Value addition of cottonseed meal for feed industries by degossypolization employing papain and solvent - Res. J. Biotechnol., 14 (11).

Kumar, M., Potkule, J., Saxena, S. and Patil, P. G. (2018) - Value-addition of cottonseed: Protein extraction, functional characterization and its application - Cotton Res. J., 9(1-2): 51-57

Li, Z., Smith, K. H. and Stevens, G. W. (2016) - The use of environmentally sustainable bio-derived solvents in solvent extraction applications—A review - Chin. J. Chem. Eng., 24: 215–220.

Mirghani, M. E. S. and Che Man, Y. B. (2003) - A new method for determining gossypol in cottonseed oil by FTIR spectroscopy - J. Am. Oil Chem. Soc.,80(7):625–628.

Nakanishi, K. and Solomon P. H. (1977) - Infrared Absorption Spectroscopy (2nd Ed.), Holden-Day, San Francisco, pp.1–5.

Pelitire, S. M., Dowd, M. K. and Cheng, H. N. (2014) - Acidic solvent extraction of gossypol from cottonseed meal - Animal Feed Sci. Technol., 195:120–128.

Singh, S., Sharma, S. K. and Kansal, S. K. (2015) - Extraction of Gossypol from Cottonseed -Review in Adv. Sci. Eng., 4:301–318.

Stuart, B. (1996) - Modern Infrared Spectroscopy, (D. J. Ando, ed.), John Wiley and Sons, New York, 135.

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Submitted

2021-08-16

Published

2021-08-16

How to Cite

Extraction and Functional Group Analysis of Gossypol from Cottonseed Meal. (2021). Cotton Research Journal, 10(1). https://epubs.icar.org.in/index.php/CoRJ/article/view/114037