Status and way-forward in breeding potato (Solanum tuberosum) for resistance to late blight


Abstract views: 830 / PDF downloads: 697

Authors

  • J GOPAL ICAR-Central Potato Research Institute, Shimla, Himachal Pradesh 171 001, India

https://doi.org/10.56093/ijas.v93i1.119721

Keywords:

Late blight, Phytophthora infestans, Potato Breeding, R/Rpi genes

Abstract

Improving host resistance to late blight (Phytophthora infestans) has been a major concern of potato breeders since the Irish famine of 1840s. Since then, a number of late blight resistant potato (Solanum tuberosum L.) cultivars have been developed using both conventional and molecular techniques. However, resistance to late blight did not last long and broke down due to the emergence of more virulent races of Phytophthora infestans. This perspective paper presents the status of sources of resistance to late blight, defence mechanism of host against the pathogen and late blight resistance genes mapped, cloned, and transferred to cultivated potato. Considerable progress has been made in all aspects of breeding potato for resistance to late blight. However, a critical appraisal of the status of potato breeding for resistance to late blight suggests the continued need to identify new sources of resistance, transfer of resistance genes from diverse sources and stacking them in maximum number into individual plants. Other breeding strategies to combat this dreaded disease are also discussed.

Downloads

Download data is not yet available.

References

Alvarez M F, Angarita M, Delgado M C, Garcıa C, Jimenez-Gomez J and Gebhardt C. 2017. Identification of novel associations of candidate genes with resistance to late blight in Solanum tuberosum Group Phureja. Frontiers in Plant Science 8: 1040. https://doi.org/10.3389/fpls.2017.01040 PMID: 28674545

Barone A. 2004. Molecular marker-assisted selection for potato breeding. American Journal of Potato Research 81: 111–17. https://doi.org/10.1007/BF02853608

Bethke P C, Halterman D A and Jansky S H. 2019. Potato germplasm enhancement enters the genomics era. Agronomy 9: 1–20.

Birch P R, Boevink P C, Gilroy E M, Hein I, Pritchard L and Whisson S C. 2008. Oomycete RXLR effectors: Delivery, functional redundancy and durable disease resistance. Current Opinion in Plant Biology 11: 373–79.

Blossei J, Gabelein R, Hammann T and Uplmoor R. 2022. Late blight resistance in wild potato species-Resources for future potato (Solanum tuberosum) breeding. Plant Breeding 141: 314–31. https://doi.org/10.1111/pbr. 13023

Bradeen J M and Kole C. 2011. Genetics, Genomics and Breeding of Potato. Science Publisher Enfield, New Hampshire, USA.

Bradeen J M, Iorizzo M, Mollov D S, Raasch J, Kramer L C, Millett B P, Austin-Phillips S, Jiang J M and Carputo D. 2009. Higher copy numbers of the potato RB transgene correspond to enhanced transcript and late blight resistance levels. Molecular Plant-Microbe Interaction 22: 437–46.

Bradshaw J E. 2009. Potato breeding at the Scottish plant breeding station and the Scottish Crop Research Institute: 1920–2008. Potato Research 52: 141–72.

Braun S R, Endelman J B, Haynes K G and Jansky S H. 2017. Quantitative trait loci for resistance to common scab and cold induced sweetening in diploid potato. Plant Genome 10: 1–9. https://doi.org/10.3835/plantgenome2016.10.0110

Cesari S. 2017. Multiple strategies for pathogen perception by plant immune receptors. New Phytologist 219: 17–24.

Corwin J A and Kliebenstein D J. 2017. Quantitative resistance: More than just perception of a pathogen. Plant Cell 29: 655–65. https://doi.org/10.1105/tpc.16.00915 PMID: 28302676

Du J, Verzaux E, Chaparro-Garcia A, Bijsterbosch G, Keizer L C P, Zhou J, Liebrand T W H, Xie C, Govers F, Robatzek S, van der Vossen E A G, Jacobsen E, Visser R G F, Kamoun S and Vleeshouwers V G A A. 2015. Elicitin recognition confers enhanced resistance to Phytophthora infestans in potato. Nature and Plants 1: 15034.

Elanhal A S M, Li J, Wang X, Zhou C, Wen G, Wang J, Lindqvist- Kreuze H, Meng Y and Shan W. 2020. Identification of natural resistance mediated by recognition of Phytophthora infestans effector gene Avr-3a EM in potato. Frontiers in Plant Science 11: 919. https://doi.org/10.3389/fpls.2020.00919

Enciso-Rodriguez F, Douches D, Lopez-Cruz M, Coombs J and de los Campos G. 2008. Genomic Selection for late blight and common scab resistance in tetraploid potato (Solanum tuberosum). G3- Genes, Genomics, Genetics 8: 2471–81.

Flor H H. 1971. Current status of the gene-for-gene concept. Annual Review of Plant Phytopathology 9: 275–96.

Foster S J, Park T H, Pel M, Brigneti G, Sliwka J, Jagger L, van der Vossen E and Joness J D G. 2009. Rpi-vnt1, a Tm-22 homolog from Solanum venturii, confers resistance to potato late blight. Molecular Plant-Microbe Interaction 22: 589–600. https://doi: 10.1094/MPMI-22-5-0589

Fry W E. 2008. Phytophthora infestans: the plant (and R gene) destroyer. Molecular Plant Pathology 9: 385–402.

Fry W E, Goodwin S B, Matuszak J M, Spielman L J, Milgroom M G and Drenth A. 1992. Population genetics and intercontinental migrations of Phytophthora infestans. Annual Review of Phytopathology 30: 107–30.

Gebhardt C and Valkonen J P T. 2001. Organization of genes controlling disease resistance in the potato genome. Annual Review of Phytopathology 39: 79–102. https://doi.org/10.1146/ annurev.phyto.39.1.79 PMID:11701860

Gebhardt C, Ballvora A, Walkemeier B, Oberhagemann P and Schuler K. 2004. Assessing genetic potential in germplasm collections of crop plants by marker-trait association: A case study for potatoes with quantitative variation of resistance to late blight and maturity type. Molecular Breeding 13: 93–102. https://doi.org/10.1023/B:MOLB.0000012878.89855.df

Ghislain M, Byarugaba A A, Magember E, Njoroge A, Rivera C, Roman M L, Tovar J C, Gamboa S, Forbers G A and Kreuze J F. 2019. Stacking three late blight resistance genes from wild species directly into African highland potato varieties confers complete field resistance to local blight races. Plant Biotechnology Journal 17: 1119–29.

Gopal J. 1998. General combining ability and its repeatability in early generations of potato breeding programmes. Potato Research 41: 21–28.

Gopal J and Singh B P. 2002. Field evaluation of potato germplasm for foliage resistance to late blight (Phytophthora infestans). (In) Proceedings of GILB' 2002 International Conference, CIP, Hamburg, Germany, July 11–13, pp. 30.

Gopal J and Singh B P. 2003/2004. Screening potatoes for resistance to late blight (Phytophythora infestans) under field conditions. Potato Research 46: 47–56.

Hajianfar R, Polgar Z S, Wolf I, Takács A, Cernak I and Taller J. 2014. Complexity of late blight resistance in potato and its potential in cultivar improvement. Acta Phytopathologica et Entomologica Hungarica 49: 141–61. https://doi: 10.1556/ APhyt.49.2014.2.2

Haverkort A J, Struik P C, Visser R G F and Jacobsen E. 2009. Applied biotechnology to combat late blight in potato caused by Phytophthora infestans. Potato Research 52: 249–64. https://doi:10.1007/s11540-009-9136-3

Hein I, Birch P R J, Danan S, Lefebvre V, Odeny D A, Gebhardt C, Trognitz F and Bryan G J. 2009. Progress in mapping and cloning qualitative and quantitative resistance against Phytophthora infestans in potato and its wild relatives. Potato Research 52: 215–27.

Jo K-R, Zhu S, Bai Y, Hutten R C B, Kessel G J T, Velushouwers V G A A, Jacobsen E and Visser R G F. 2016. Problematic crops: 1. Potatoes: Towards sustainable potato late blight resistance by cisgenic R gene pyramiding. Plant Pathogen Resistance Biotechnology, pp. 171–91. Collinge DB (Ed.). John Wiley & Sons, Inc, New Jersy, USA.

Juyo Rojas D K, Sedano S, Ballvora J C, Leon A J and Vasquez M T. 2019. Novel organ-specific genetic factors for quantitative resistance to late blight in potato. PLoS One 14(7): e0213818. https://doi.org/10.1371/journal.pone.0213818

Kaushik S K, Birhman R K, Singh B P and Gopal J. 2000. Combining ability and heterosis for field resistance to late blight in potato (Phytophythora infestans). Indian Journal of Agricultural Sciences 70: 55–56.

Keizer P, Lammerts van Bueren E T, Engelen C J M and Hutten R C B. 2022. Breeding late blight resistant potatoes for organic farming- a collaborative model of participatory plant breeding: the Bioimpuls project. Potato Research 65: 349–77. https://doi.org/10.1007/s11540-021-09519-8

Kieu N P, Lenman M, Wang E S, Peterson B L and Andreasson E. 2021. Mutation introduced in susceptibility genes through CRISPR/Cas 9 genome editing confer increased late blight resistance in potatoes. Scientific Reports 11: 4487. https://doi. org/10.1038/s41598-021-83972-w

Killick R J and Malcolmson J F. 1973. Inheritance in potatoes of field resistance to late blight [Phytophthora infestans (Mont.) de Bary] Physiology and Plant Pathology 3: 121–31.

Kramer L C, Choudoir M J, Wielgus S M, Bhaskar P B and Jiang J M. 2009. Correlation between transcript abundance of the RB gene and the level of the RB-mediated late blight resistance in potato. Molecular Plant-Microbe Interaction 22: 447–55.

Kumar V, Gopal J and Dhiman K R. 2005. Combining ability analysis for tuber yield and late blight in potato. Potato Journal 32: 129–30.

Kumar R and Gopal J. 2006. Repeatability of progeny mean, combining ability, heterosis and heterobeltiosis in early generations of a potato breeding programme. Potato Research 49: 131–41.

Kumar R, Kang G S and Pandey S K. 2007. Inheritance of resistance to late blight (Phytophtora infestans) in potato. Euphytica 155: 183–91. https://doi 10.1007/s10681-006-9320-3

Lindhout P, Meijer D, Schotte T, Hutten R C B, Visser R G F and van Eck H J. 2011. Towards F1 hybrid seed potato breeding. Potato Research 54: 301–12.

Lindqvist-Kreuze H, de Boeck B, Unger P, Gemenet D, Li X, Pan Z, Sui Q, Qin J, Woldegjorgis G, Negash K, Seid I, Hirut B, Gastelo M, De Vega J and Bonierbale M. 2020. Global multi-environment resistance QTL for foliar late blight resistance in tetraploid potato with tropical adaptation. Report International Potato Center, Lima, Peru. https://doi.org/10.1101/2020.02.16.950618

Lokossou A A, Park T-H, van Arkel G, Arens M, Ruyter-Spira C, Morales J, Whisson S C, Birch P R J, Visser R G F, Jacobsen E and van der Vossen E A G. 2009. Exploiting knowledge of R/Avr genes to rapidly clone a new LZ-NBS-LRR family of late blight resistance genes from potato linkage group IV. Molecular Plant-Microbe Interaction 22: 630–41. https:// doi: 10.1094/MPMI-22-6-0630

Malcolmson J F and Killick R J. 1980. The breeding value of potato parents for field resistance to late blight measured by whole seedlings. Euphytica 29: 489–95.

Malosetti M, Van Der Linden C G, Vosman B and Van Eeuwijk F A. 2007. A mixed-model approach to association mapping using pedigree information with an illustration of resistance to Phytophthora infestans in potato. Genetics 175: 879–89. https://doi.org/10.1534/genetics.105.054932

Meade F, Hutten R, Wagener S, Prigge V, Dalton E, Kirk H G, Gri D and Milbourne D. 2020. Detection of novel QTLs for late blight resistance derived from the wild potato species Solanum microdontum and Solanum pampasense. Genes 11: 1–18.

Meuwissen, T H E, Hayes B J and Goddard M E. 2001. Prediction of total genetic value using genome-wide dense marker maps. Genetics 157: 1819–29.

Mosquera T, Alvarez M F, Jimenez-gomez J M, Draffehn A and Hofmann A. 2016. Targeted and untargeted approaches unravel novel candidate genes and diagnostic SNPs for quantitative resistance of the potato (Solanum tuberosum L.) to Phytophthora infestans causing the late blight disease. PLoS One 11: e0156254.

Muktar M S, Lübeck J, Strahwald J and Gebhardt C. 2015. Selection and validation of potato candidate genes for maturity corrected resistance to Phytophthora infestans based on differential expression combined with SNP association and linkage mapping. Frontiers in Genetics 6: 1–19. https://doi. org/10.3389/fgene.2015.00294

Nachtigall M, König J and Thiema R. 2018. Mapping of a novel, major late blight resistance locus in the diploid (1EBN) Mexican Solanum pinnatisectum Dunal on chromosome VII. Plant Breeding 137: 433-442. https://doi:10.1111/pbr.12580

Namugga P, Sibiya J, Melis R and Berekye A. 2020. Combining ability analysis of yield and resistance to late blight disease caused by Phytophthora infestans in Uganda. Australian Journal of Crop Scieince 14: 1637–40. https://doi.10.21475/ajes.20.14.90.p24137

Nowicki M, Foolad MR, Nowakowska M and Kozik E U. 2011. Potato and tomato late blight caused by Phytophthora infestans: An overview of pathology and resistance breeding. Plant Disease 96: 4–17. https://doi.org/10.1094/PDIS-05-11-0458 PMID: 30731850

Pajerowska-Mukhtar K, Stich B, Achenbach U, Ballvora A, Lubeck J and Strahwald J. 2009. Single nucleotide polymorphisms in the allene oxide synthase 2 gene are associated with field resistance to late blight in populations of tetraploid potato cultivars. Genetics 181: 1115–27. https://doi.org/10.1534/genetics.108.094268 PMID: 19139145

Paluchowska P, Sliwka J and Yin Z. 2022. Late blight resistance genes in potato breeding. Planta 255: 1–20. https://doi.org/10.1007/s00425-022-03910-6

Pavan S, Schiavulli A, Appiano M, Marcotrigiano A R, Cillo F, Visser R G F, Bai Y, Lotti C and Ricciardi L. 2011. Pea powdery mildew er1 resistance is associated to loss-of-function mutations at a MLO homologous locus. Theoretical and Applied Genetics 123: 1425–31.

Pel MA, Foster SJ, Park T H, Rietman H, van Arkel G, Jones J D, Van Eck H J, Jacobsen E, Visser R G and van der Vossen E A G. 2009. Mapping and cloning of late blight resistance genes from Solanum venturii using an interspecific candidate gene approach. Molecular Plant-Microbe Interaction 22: 601–15. https://doi.org/10.1094/MPMI-22-5-0601

Rodewald J and Trognitz B. 2013. Solanum resistance genes against Phytophthora infestans and their corresponding avirulence genes. Molecular Plant Pathology 14: 740–57. https://doi.org/10.1111/mpp.12036

Rogozina E V. Beketova M P, Muratova O A, Kuznetsova M A and Khavkin E. 2021. Stacking resistance genes in multiparental interspecific potato hybrids to anticipate late blight outbreaks. Agronomy 11: 1–31. https://doi.org/10.3390/agronomy11010115

Rokosy-Tican E, Thieme R, König J, Nachtigall M, Hammann T, Demes T-E, Kruppa K and Molnr-Lang M. 2020. Introgression of two broad-spectrum late blight resistance genes, Rpi-BlB1 and Rpi-Blb3, from S. bulbocastanum Dun plus race –specific R genes into potato pre-breeding lines. Frontiers in Plant Science 11: 699. https://doi.org/10.3389/fp;s.2020.00699

Simko I. 2004. One potato, two potato: haplotype association mapping in autotetraploids. Trends in Plant Science 9: 441–48. https://doi.org/10.1016/j.tplants.2004.07.003 PMID: 15337494

Sliwka J, Brylinska M, Stefanczyk E, Plich J, Smyda-Dajmund P and Sobkowiak S. 2019. Breeding of potato resistant to late blight using genetic resources and DNA markers. Current Challenges in Plant Genetics, Genomics, Bioinformatics and Biotechnology 1: 214–16. https://doi:10.18699/ICG-PlantGen2019-69

Smart C D and Fry W E. 2001. Invasions by the late blight pathogen: renewed sex and enhanced fitness. Biological Invasions 3: 235-43.

Song J Q, Bradeen J M, Naess S K, Raasch J A, Wielgus S M, Haberlach G T, Liu J, Kuang H H, Austin-Phillips S, Buell C R, Helgeson J P and Jiang J M. 2003. Gene RB cloned from Solanum bulbocastanum confers broad spectrum resistance to potato late blight. Proceedings National Academy of Sciences (USA) 100: 9128–33. https://doi.org/10.1073/pnas.1533501100

Su Y, Viquez-Zamora, M, Uill D, Sinnige J, Kruyt H, Vossen J, Lindhout P and Heusden S V. 2020. Introgression of genes for resistance against Phytophthora infestans in diploid potato. American Journal of Potato Research 97: 33–42. https://doi.org/10.1007/s12230-019-09741-8

Sun K, Wolters A M A, Vossen J H, Rouwet M E, Loonen A E H M, Jacobsen E, Visser R G F and Bai Y. 2016. Silencing of six susceptibility genes results in potato late blight resistance. Transgenic Research 25: 731–42. https://doi. 10.1007/s11248- 016-9964-2

Sundaresha, Sharma S, Shandil R K, Sharma S, Thakur V, Bhardwaj V, Kaushik S K, Singh B P and Chakrabarti S K. 2018. An insight into the downstream analysis of RB gene in F1 RB potato lines imparting field resistance to late blight. Functional Plant Biology 45(10): 1026–37. https://doi.org/10.1071/FP17299

Syverson R L and Bradeen J M. 2011. A novel class of simple PCR markers with SNevel sensitivity for mapping and haplotype characterization in Solanum species. American Journal of Potato Research 88: 269–82.

Tao Y, Xie Z, Chen W, Glazebrook J, Chang H S, Han B, Zhu T, Zou G and Katagiri F. 2003. Quantitative nature of Arabidopsis responses during compatible and incompatible interactions with the bacterial pathogen Pseudomonas syringae. Plant Cell 15: 317–30.

Thomma B P, Nürnberger T and Joosten M H. 2011. Of PAMPs and effectors: the blurred PTI-ETI dichotomy. Plant Cell 23: 4–15.

Tiwari J K, Siddappa S, Singh B P, Kaushik S K, Chakrabarti S K, Bhardwaj V and Chandel P. 2013. Molecular markers for late blight resistance breeding of potato: an update. Plant Breeding 132: 237–45.

Tsuda K and Katagiri F. 2010. Comparing signalling mechanisms engaged in pattern-triggered and effector-triggered immunity. Current Opinion in Plant Biology 1: 459–65.

Tung P X, Vander Zaag P, Li C and Tang W. 2018. Combining ability for foliar resistance to late blight [Phytophythora infestans (Mont.) de Bary] of potato cultivars with different levels of resistance. American Journal of Potato Research 95: 670–78.

van Os H. Andrzejewski S, Bakker E, Barrena I, Bryan G J, Caromel B, Ghareeb B, Isidore E, de Jong W, van Koert P, Lefebvre V, Milbourne D, Ritter E, Jeroen N A M, van der Voort R, Rousselle-Bourgeois F, van Vliet J, Waugh R, Visser R G F, Bakker J and van Eck H J. 2006. Construction of a 10,000-marker ultradense genetic recombination map of potato: providing a framework for accelerated gene isolation and a genome wide physical map. Genetics 173: 1075–87.

Van Weymers P S M, Baker K, Chen X, Harrower B, Cooke D E L, Gilroy E M, Birch P R J, Thilliez G J A, Lees A K, Lynott J S, Armstrong M R, McKenzie G, Bryan G J and Hein I. 2016. Utilizing “Omic” technologies to identify and prioritize novel sources of resistance to the oomycete pathogen Phytophthora infestans in potato germplasm collections. Frontiers in Plant Science 7: 672. https://doi.org/10.3389/fpls.2016.00672

Vleeshouwers, V G, Raffaele S, Vossen J, Champouret N, Oliva R, Segretin M E and Kamoun S. 2008. Understanding and exploiting late blight resistance in the age of effectors. Annual Review of Phytopathogy 49: 507–31.

Vleeshowers V G, Finkers R, Budding D, Visser M, Jacobs M M J, van Berloo R, Pel M, Champouret N, Bakker E, Krenek P, Rietman H, Huigen D, Hoekstra R, Goverse A, Vosman B, Jacobsen E and Visser R G F. 2011. SolRgenes: an online database to explore disease resistance genes in tuber-bearing Solanum species. BMC Plant Biology 11: 116.

Yang Y, Jiang R, Wang H, Tian Z and Xie C. 2020. StPOPA, encoding an anionic peroxidase, enhances potato resistance against Phytophthora infestans. Molecular Breeding 40: 16. https://doi.org/10.1007/s11032-019-1093-1

Yuen J. 2021. Pathogens which threaten food security: Phytophthora infestans, the potato late blight pathogen. Food Security 13: 247–53. https://doi.org/10/10071/s12571-021-001141-3

Downloads

Submitted

2022-01-02

Published

2023-01-17

Issue

Section

Review Article

How to Cite

GOPAL, J. (2023). Status and way-forward in breeding potato (Solanum tuberosum) for resistance to late blight. The Indian Journal of Agricultural Sciences, 93(1), 03–10. https://doi.org/10.56093/ijas.v93i1.119721
Citation