Onion (Allium cepa L.) as an ancient potential source of Vitamin C for boosting immune functionality


31

Authors

  • ANIL KHAR Indian Agricultural Research Institute
  • Hira Singh

https://doi.org/10.56093/ijas.v96i10.175116

Keywords:

Allium cepa L., Ascorbic acid, Bulb onion, Immunity, Vitamin C

Abstract

Bulb onions (Allium cepa L.), consumed worldwide, possessed essential oils that give distinct flavour and aroma to the food. Globally, onion is a very well accepted vegetable crop due to its medicinal and nutritional values as well as its unique and peculiar flavour, mostly as a result of the crop's several potential culinary, processing and industrial uses. Its bulbs contain high amounts of essential nutrients such as proteins, essential amino acids, vitamins C, macro- and micro-minerals, as well as several bioactive compounds. Nevertheless, its value as an important source of vitamin C explicitly is unrecognized. This vitamin is a crucial component of the living cellular systems for numerous metabolic purposes and as a powerful antioxidant to alleviate oxidative stresses. Significant diversity in the concentration of vitamin C among onion genotypes was documented in scientific reports. Its concentration varied with bulb colour considerably. White coloured bulb onions possessed lesser compared to red coloured bulbs. This compiled information in this review paper could be of immense help for food scientists and nutritionists as well as future onion breeding for developing new cultivars with higher concentrations of vitamin C to ensure nutritional security and boosting immunity. Herbal based bioactive compounds or nutraceuticals is better option than to consume synthetic supplements or drugs for a specific or general ailment. In the 21st century, a principle “Food as Medicine” is gaining an immense focus of scientists across several disciplines and hence, the systematic research work on bulb onions might certainly play a major role in the future.

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Author Biography

  • ANIL KHAR, Indian Agricultural Research Institute
    Principal Scientist

References

1. Armand, A.B.; Scher, J.; Aboubakar, G.A.; Roger, P.; Montet, D.; Moses, M.C. Effect of three drying methods on the physicochemical composition of three varieties of onion (Allium cepa L.). J. Food Sci. Nutr. 2018, 1, 17–24

2. Ashwini, M., Balaganesh, J., Balamurugan, S., Murugan, S. B., & Sathishkumar, R. (2013). Antioxidant activity in in vivo and in vivo cultures of onion varieties (Bellary and CO 3). Food and Nutrition Sciences, 4, 918-923

3. Bahorun, T., Luximon-Ramma, A., Crozier, A., & Aruoma, O. I. (2004). Total phenol, flavonoid, proanthocyanidin and vitamin C levels and antioxidant activities of Mauritian vegetables. Journal of the Science of Food and Agriculture, 84(12), 1553–1561. doi:10.1002/jsfa.1820

4. Barrales-Heredia, S.M.; Grimaldo-Juárez, O.; Suárez-Hernández, Á.M.; González-Vega, R.I.; Díaz-Ramírez, J.; García-López, A.M.; Soto-Ortiz, R.; González-Mendoza, D.; Iturralde-García, R.D.; Dórame-Miranda, R.F.; et al. (2023) Effects of Different Irrigation Regimes and Nitrogen Fertilization on the Physicochemical and Bioactive Characteristics of onion (Allium cepa L.). Horticulturae 9: 344. https://doi.org/10.3390/horticulturae9030344

5. Bystrická et al (2010) Böttcher, C., Krähmer, A., Stürtz, M., Widder, S. and Schulz, H. 2018. Effect of cultivar and cultivation year on the metabolite profile of onion bulbs (Allium cepa L.). J. Agric. Food Chem. 66: 3229-38.

6. Campos, F. M., Ribeiro, S. M. R., Della Lucia, C. M., Pinheiro-Sant'Ana, H. M. and Stringheta, P. C. 2009. Optimization of methodology to analyze ascorbic and dehydroascorbic acid in vegetables. Química Nova, 32: 87-91.

7. Carr, A. C. and Rowe, S. 2020. The emerging role of vitamin C in the prevention and treatment of COVID-19. Nutrients. 12: 3286.

8. Carr, A. C., and Maggini, S. (2017). Vitamin C and immune function. Nutrients, 9(11), 1211.

9. Crozier, A., Lean, M. E. J., McDonald, M. S. and Black, C. 1997. Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery. J. Agric. Food Chem. 45: 590-95.

10. Dahlawi, S. M., Akhtar, A., Nazir, W., Ahmed, Z., & Khalid, N. (2022). Characterisation of O/W emulsions encapsulating ergocalciferol using onion skin waste saponins: insights on formulation and release properties. International Journal of Food Science & Technology, 57(2), 1317-1324.

11. Dhumal, K., Datir, S. and Pandey, R. 2007. Assessment of bulb pungency level in different Indian cultivars of onion (Allium cepa L.). Food Chem. 100: 1328-30.

12. Elhassaneen Y A. (2006) Phenolic compounds, sweetness and amino acids content of onion cultivars distributed in Egyptian local markets and their relationship with antioxidant activities. J. Product. & Dev. 11 (2): 297-315

13. Elhassaneen, Y. A. and Sanad, M. I. 2009. Phenolics, selenium, vitamin C, amino acids and pungency levels and antioxidant activities of two Egyptian onion varieties. Am. J. Food Technol. 4: 241-54.

14. Golubkina, N.; Amalfitano, C.; Sekara, A.; Tallarita, A.; Pokluda, R.; Stoleru, V.; Cuciniello, A.; Agafonov, A.F.; Kalisz, A.; Hamburdă, S.B.; et al. (2022) Yield and bulb quality of storage onion cultivars as affected by farming system and nitrogen dose. Sci. Hortic., 293, 110751.

15. Gulsen, G., & Ayaz, E. (2010). Antimicrobial effect of onion (Allium cepa) and traditional medicine. Journal of Animal and Veterinary Advances, 9, 1680-5593.

16. Hallmann, E. and E. Rembiałowska, 2006. Antioxidant compounds content in selected onion bulbs from organic and conventional cultivation. Journal of Research and Applications in Agricultural Engineering, 51: 42-46

17. ICMR. 2010. Nutrient requirement and recommended dietary allowances for Indians. A report of the Expert Group of the Indian Council of Medical Research.

18. Iqbal, K., Khan, A. and Khattak, M. A. K. 2004. Biological significance of ascorbic acid (vitamin C) in human health-a review. Pak. J. Nutr. 3: 5-13.

19. Jeong, C. H., Kim, J. H., & Shim, K. H. (2006). Chemical components of yellow and red onion. Journal of the Korean Society of Food Science and Nutrition, 35(6), 708–712.

20. Jurgiel-Malecka, G., Gibczynska, M., & Nawrocka-Pezik, M. (2015). Comparison of chemical composition of selected cultivars of white, yellow and red onions. Bulgarian Journal of Agricultural Science, 21(4), 736-741.

21. Khar A, Singh H (2020) Rapid Methods for Onion Breeding. In Accelerated Plant Breeding, Volume 2 (pp. 77-99). Springer, Cham.

22. Khar A, Zimik M, Verma P, Singh H, Mangal M, Singh M C, Gupta A J (2022) Molecular marker-based characterization of cytoplasm and restorer of male sterility (Ms) locus in commercially grown onions in India. Molecular Biology Reports 49(6): 5535-5545.

23. Klein, B. P., & Perry, A. K. (1982). Ascorbic acid and vitamin A activity in selected vegetables from different geographical areas of the United States. Journal of Food Science, 47(3), 941-945.

24. Kuiper, C., & Vissers, M. (2014). Ascorbate as a co-factor for Fe-and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression. Frontiers in oncology, 4, 117223.

25. Kumari, P., Dembra, S., Dembra, P., Bhawna, F., Gul, A., Ali, B., Sohail, H., Kumar, B., Memon, M. K. and Rizwan, A. 2020. The role of vitamin C as adjuvant therapy in COVID-19. Cureus 12: e11779.

26. Lachman, J., Orsak, M., & Pivec, V. (1999). Flavonoid antioxidants and ascorbic acid in onion (Allium cepa). Zahradnictvi-UZPI (Czech Republic), 26(4), 125–135.

27. Ma, Y. L., Zhu, D. Y., Thakur, K., Wang, C. H., Wang, H., Ren, Y. F., ... & Wei, Z. J. (2018). Antioxidant and antibacterial evaluation of polysaccharides sequentially extracted from onion (Allium cepa L.). International journal of biological Macromolecules, 111, 92-101.

28. Mitra, J., Shrivastava, S. Á. and Rao, P. S. 2012. Onion dehydration: a review. J. Food Sci. Technol. 49: 267-77.

29. Mota, C. L., Luciano, C., Dias, A., Barroca, M. J. and Guiné, R. F. 2010. Convective drying of onion: Kinetics and nutritional evaluation. Food Bioprod. Process. 88: 115-23.

30. Ncayiyana, M.; Bertling, I.; Maboko, M.M. (2018) Yield and nutritional quality of different short-day onion cultivars as affected by nitrogen application. S. Afr. J. Plant Soil, 35, 215–221.

31. Onyeoziri, U. P., Romanus, E. N., & Onyekachukwu, U. I. (2016). Assessment of antioxidant capacities and phenolic contents of Nigerian cultivars of onions (Allium cepa L.) and garlic (Allium sativum L.). Pakistan Journal of Pharmaceutical Sciences, 29(4), 1183-1188.

32. Petrovic, B., & Pokluda, R. (2020). Influence of organic fertilizers on onion quality. Pol J Environ Stud, 29(1), 517-523.

33. Rifkin, E and Lazris, A (2015). Vitamins and Supplements. Interpreting Health Benefits and Risks: A Practical Guide to Facilitate Doctor-Patient Communication, 203-212.

34. Sagar, N. A., Pareek, S., Benkeblia, N., & Xiao, J. (2022). Onion (Allium cepa L.) bioactives: Chemistry, pharmacotherapeutic functions, and industrial applications. Food Frontiers, 3(3), 380-412.

35. Samancioglu, A., Sat, I. G., Yildirim, E., Ercisli, S., Jurikova, T. and Mlcek, J. 2016. Total phenolic and vitamin C content and antiradical activity evaluation of traditionally consumed wild edible vegetables from Turkey. Ind. J. Trad. Knowl. 15: 208-13.

36. Sami, R.; Elhakem, A.; Alharbi, M.; Benajiba, N.; Almatrafi, M.; Helal, M. Nutritional Values of Onion Bulbs with Some Essential Structural Parameters for Packaging Process. Appl. Sci. 2021, 11, 2317. https://doi.org/10.3390/app11052317

37. Sellappan, S. and Akoh, C. C. 2002. Flavonoids and antioxidant capacity of Georgia-grown Vidalia onions. Journal of Agricultural and Food Chemistry, 50: 5338–42.

38. Selvamary, V. N., Brundha, M. P., & Girija, A. S. (2020). Role of Vitamin C in Immune Function of Human Body. Indian Journal of Forensic Medicine & Toxicology, 14(4).

39. Singh H, Khar A (2021) Perspectives of onion hybrid breeding in India: An overview. The Indian Journal of Agricultural Sciences 91(10): 1426–32.

40. Singh H, Lombardo M, Goyal A, Khar A (2023a) Genotypic variation in Na, K and their ratio in 45 commercial cultivars of Indian tropical onion: A pressing need to reduce hypertension among the population. Frontiers in Nutrition. 10: 1098320 https://doi:10.3389/fnut.2023.1098320

41. Singh H, Sekhon B S, Kumar P, Dhall R K, Devi R, Dhillon T S, Sharma S, Khar A, Yadav R K, Tomar B S, Ntanasi T, Sabatino L and Ntatsi G (2023b) Genetic Mechanisms for Hybrid Breeding in Vegetable Crops. Plants (12): 2294

42. Singh H, Verma P, Kumar A, Khar A (2022) Screening of forty‑five Indian short‑day onion cultivars for Vitamin C content to ensure nutritional security. Indian Journal of Horticulture 79: 160–67.

43. Singh H, Verma P, Lal S K, Khar A (2021) Optimization of EMS mutagen dose for short day Indian onion. Indian Journal of Horticulture 78(1): 35-40 https://DOI:10.5958/0974-0112.2021.00005.0

44. Singh, H. and Khar, A. 2021. Perspectives of onion hybrid breeding in India: An overview. Ind. J. Agric. Sci. 91: 1426-32.

45. Singh, H., Khar, A. and Verma, P. 2021. Induced mutagenesis for genetic improvement of Allium genetic resources: a comprehensive review. Gen. Res. Crop Evol. 68: 2669-90.

46. Singh H and Khar A (2022) Potential of onion (Allium cepa L.) as traditional therapeutic and functional food: An update. Indian Journal of Agricultural Sciences 92(11): 1291–97 https://doi.org/10.56093/ijas.v92i11.123235

47. Sorice, A., Guerriero, E., Capone, F., Colonna, G., Castello, G., & Costantini, S. (2014). Ascorbic acid: its role in immune system and chronic inflammation diseases. Mini reviews in medicinal chemistry, 14(5), 444-452.

48. Ströhle, A., Wolters, M., & Hahn, A. (2011). Micronutrients at the interface between inflammation and infection ascorbic acid and calciferol. Part 1: general overview with a focus on ascorbic acid. Inflammation & Allergy-Drug Targets, 10(1), 54-63.

49. Teshika, J. D., Zakariyyah, A. M., Zaynab, T., Zengin, G., Rengasamy, K. R., Pandian, S. K., & Fawzi, M. M. (2019). Traditional and modern uses of onion bulb (Allium cepa L.): a systematic review. Critical zhureviews in food science and nutrition, 59:39-70.

50. Ueda, Y., Tsubuku, T., & Miyajima, R. (1994). Composition of sulfur-containing components in onion and their flavor characters. Bioscience, biotechnology, and biochemistry, 58(1), 108-110.

51. Viera, V. B., Piovesan, N., Rodrigues, J. B., de O Mello, R., Prestes, R. C., Dos Santos, R. C. V., ... & Kubota, E. H. (2017). Extraction of phenolic compounds and evaluation of the antioxidant and antimicrobial capacity of red onion skin (Allium cepa L.). International Food Research Journal, 24(3), 990.

52. WHO (2004) World Health Organization. https://www.who.int/publications/i/item/9241546123

53. Wichrowska, D.; Wojdyła, T.; Rolbiecki, S.; Rolbiecki, R.; Czop, P.; Jagosz, B.; Ptach, W. (2017) Effect of nitrogen fertilization on the marketable yield and nutritive value of onion. Acta Sci. Pol. Hortorum Cultus, 16, 125–133.

54. Wilson, J. X. (2005). Regulation of vitamin C transport. Annu. Rev. Nutr., 25, 105-125.

55. Woo, A., Kim, J. H., Jeong, Y. J., Maeng, H. G., Lee, Y. T., Kang, J. S., ... & Hwang, Y. I. (2010). Vitamin C acts indirectly to modulate isotype switching in mouse B cells. Anatomy & cell biology, 43(1), 25-35.

Published

2026-10-05

Issue

Section

Review Article

How to Cite

KHAR, A., & Singh, H. (2026). Onion (Allium cepa L.) as an ancient potential source of Vitamin C for boosting immune functionality. The Indian Journal of Agricultural Sciences, 96(10). https://doi.org/10.56093/ijas.v96i10.175116
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