Clinical and molecular evaluation of Proteus mirabilis in a family pet dog with urolithiasis
334 / 420
Authors
-
T. Ranjith Vimalraj
-
P. Selvaraj
-
K. Senthilkumar
-
P. Pothiappan
-
S. Kavitha
Keywords:
Proteus mirabilis, dog, struvite crystals.Abstract
Urinary tract infections are a major concern in family pet dogs. Golden Retriever dog was found to have urinary incontinence, haematuria, stranguria and foul-smelling urine. Radiography and ultrasonography confirmed multiple nephroliths in the right kidney and urethral calculi measuring 5.28 mm. Elevated BUN, creatinine, phosphorus, anemia, haematuria, proteinuria, and struvite crystalluria were noticed. The isolation and characterization of Proteus mirabilis, using both conventional and molecular methods, including 16S rRNA gene sequencing, confirmed its association with urolithiasis. Urethral calculi were relieved by retrograde urohydropropulsion, and the dog was treated with Amoxicillin-Clavulanate along with dietary and supportive therapy. Post-treatment urinalysis by the fourth week showed no abnormalities, indicating clinical improvement.
Downloads
References
1. Aurich, S., Prenger-Berninghoff, E. and Ewers, C. 2022. Prevalence and Antimicrobial
2. Resistance of Bacterial Uropathogens Isolated from Dogs and Cats. Antibiotics 11:
3. 1730.
4. Chauhan, V., Katoch, A., Sharma, A., Patil, R. D. and Kumar, A. 2025. Haematobiochemical
5. examination and urinalysis in dogs with renal disease. Indian J. Vet. Med., 45(1): 21–
6. 24.
7. Decome, M., Cuq, B., Fairbrother, J. H., Gatel, L. and Conversy, B. 2020. Clinical
8. significance of Proteus mirabilis bacteriuria in dogs: Risk factors and antimicrobial
9. susceptibility. Can. J. Vet. Res., 84(4): 252–258.
10. Devipriya, K., Lavanya, C., Selvaraj, P. and Napolean, R. E. 2018. Early diagnosis of renal
11. insufficiency in dogs with haemato-biochemical findings. J. Entomol and
12. Zoology Studies, 6(5):703–705.
13. Harada, K., Niina, A., Shimizu, T., Mukai, Y., Kuwajima, K., Miyamoto, T. and Kataoka, Y.
14. 2014. Phenotypic and molecular characterization of antimicrobial resistance in
15. Proteus mirabilis isolates from dogs. J. Med. Microbiol., 63:1561–1567.
16. Singh, K., Raghunath, M. and Gill, J. P. S. 2011. Bacteriological evaluation of urine, bladder
17. mucosal biopsy and uroliths in dogs suffering from urolithiasis. Indian J. Anim. Sci.,
18. 76(1).
19. Smarick, S. D., Haskins, S. C., Aldrich, J., Foley, J. E., Kass, P. H., Fudge, M. and Ling, G.
20. V. 2004. Incidence of catheter-associated urinary tract infection among dogs in a
21. small animal intensive care unit. J. Am. Vet. Med. Assoc., 224(12):1936-40.
22. Sonu, Kumar, A., Charaya, G., Bangar, Y., Agnihotri, D. and Kumar, T. 2019. Haemato-
23. biochemical alterations in dogs suffering from chronic renal failure. Indian J. Vet.,
24. Med. 39(1): 31–35.
25. Subapriya, S., Vairamuthu, S., Chandrasekar, M., Balagangatharathilagar, M., Ramesh, S.,
26. Areshkumar, M. and Thangaraj, M J. 2020. Clinicopathological profile of canine renal
27. disorders. J. Entomol. and Zoology Studies, 8(2): 770–774.
28. Warren, J. W., Tenney, J. H., Hoopes, J. M., Muncie, H. L. and Anthony, W. C. 1982. A
29. prospective microbiologic study of bacteriuria in patients with chronic indwelling
30. urethral catheters. J. Infectious Diseases, 146(6): 719–723.
31. Weese, J. S., Blondeau, J., Boothe, D., Breitschwerdt, E., Guardabassi, L., Hillier, A., Lloyd,
32. D. H., Papich, M., Rankin, S., Turnidge, J. and Sykes, J. 2019. International Society
33. for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis
34. and management of bacterial urinary tract infections in dogs and cats. Vet. J,. 247: 8–
35. 25.
36. Wong, C., Epstein, S. E. and Westropp, J. L. 2015. Antimicrobial susceptibility patterns in
37. urinary tract infections in dogs (2010–2013). J. Vet. Internal Med., 29(4): 1045–1052.
Downloads
Published
Issue
Section
License
Copyright policy of the journal requires author to delegate all the copyrights to Indian Society for Veterinary Medicine.How to Cite
