Mammary Tumors in dogs: Age, Breed, Gender, Rearing, and Diet Factors


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Authors

  • S. Sruthi Department of Veterinary Pathology, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • K.S. Prasanna Department of Veterinary Pathology, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • A.J.George Department of Veterinary Pathology, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • I.S Sajitha Department of Veterinary Pathology, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • S.N. Sudheesh Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • P.P. Varuna Department of Veterinary Biochemistry, College of Veterinary and Animal Sciences, KVASU, Mannuthy
  • R. Bharathi Department of Veterinary Pathology, College of Veterinary and Animal Sciences, KVASU, Mannuthy

https://doi.org/10.62757/IVA.2024.101.2.34-38

Keywords:

Tumor, risk factors, age

Abstract

Mammary neoplasms, are the second most common canine cancer type that pose a significant health concern for the dogs. This research explores the prevalence and identifies various risk factors associated with their occurrence. Among 45 confirmed cases, mammary tumors were most common in dogs aged 8 to 12 years. Female dogs were more susceptible, attributed to estrogen's effect on mammary glands. The highest occurrence of mammary tumors was identified in Labrador Retrievers and Crossbred dogs. The highest incidence of CMTs was noted in the inguinal mammary gland. Following this, the caudal abdominal gland, cranial thoracic mammary gland, while the caudal thoracic glands accounted the least number of cases. In the current study, there was higher incidence of neoplasms in underweight dogs and in owned dogs reared in outdoors. This study provides insights into the epidemiology of mammary tumors in dogs, with respect to  age, gender, breed, environmental exposures, and dietary practices as significant.

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References

Ariyarathna, H., De Silva, N., Aberdein, D., Kodikara, D., Jayasinghe, M., Adikari, R. and Munday, J.S. (2018) Clinicopathological diversity of canine mammary gland tumors in Sri Lanka: A one-year survey on cases presented to two veterinary practices. Vet. Sci. 5(2): 46.

Arnold, K., Sarkar, A., Yram, M.A., Polo, J.M., Bronson, R., Sengupta, S., Seandel, M., Geijsen, N. and Hochedlinger, K. (2011) Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem cell. 9(4): 317-329.

Baba, A.I. and Câtoi, C. (2007) Mammary gland tumors in Comparative Oncology. The Publishing House of the Romanian Academy.

Ceelen, W., Pattyn, P. and Mareel, M. (2014) Surgery wound healing, and metastasis: recent insights and clinical implications. Crit. Rev. Oncol. Hematol. 1: 16-26.

Dhami, M. A., Tank, P. H., Karle, A. S., Vedpathak, H. S. and Bhatia, A. S. (2010) Epidemiology of canine mammary gland tumours in Gujarat. Vet. Wld. 3: 282.

Gupta, K., Sood, N. K., Uppal, S. K., Mohindroo, J., Mahajan, S., Raghunath, M. and Singh, K. (2012) Epidemiological studies on canine mammary tumour and its relevance for breast cancer studies. IOSR Journal of Pharmacy, 2:322-333.

Guzman, E., Langowski, J.L. and Owen-Schaub, L. (2003) Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer. Apoptosis. 8: 315-325.

Karnik, M., Anjankumar, K. R., Jeevan, K., Gowda, Y., Rakshith, K., Shettar, M., and Rao, S. (2020) Incidence and histopathological studies on tumours of dogs in Bengaluru, India. Int. J. Curr. Microbiol. Appl. Sci., 9:747-752.

Misdorp W. (2002) Tumours of mammary gland In Tumours of Domestic Animals. Mueten DJ. (4th Ed.). Lowa State Press: Blackwell Publishing Company, Oxford, UK, 109p.

Neeman, E. and Ben-Eliyahu, S. (2013) Surgery and stress promote cancer metastasis: New outlooks on perioperative mediating mechanisms and immune involvement. Brain Behav. Immun., 30:32-S40.

Nithya, P., Vairamuthu, S. and Balachandran, C. (2018) Factors influencing the occurrence of mammary gland tumours in dogs. Indian J. Vet. Pathol., 42(4):249-253.

Panchkhande, N., Dewangan, R., Kalim, M. O., Sharda, R., Ratre, H. K., Sahu, D., Sidar, S. and Yadav, S. K. (2019) Incidence of mammary tumour and venereal granuloma in canine in Durg district, Chhattisgarh, India. Int.J.Curr.Microbiol.App.Sci., 8(4): 2368-2381.

Pena, L., Silván, G., Pérez-Alenza, M.D., Nieto, A. and Illera, J.C. (2003) Steroid hormone profile of canine inflammatory mammary carcinoma: a preliminary study. J. Steroid Biochem.Mol. Biol., 84:211-216.

Raflo, C.P. and Diamond, S.S., (1980) Neoplasm of the mammary papilla in a male dog. Am. J. Vet. Res., 41(6): 953-954.

Rezia, A., Tavasoli, A., Bahonar, A. and Mehrazma, M. (2009) Grading in canine mammary gland carcinoma. J. Biol. Sci., 9: 333-338.

Sasco, A.J. (2008) Cancer and globalization. Biomed. Pharmacother., 62: 110-21.

Senthil, N.R., Chakravarthi, R. and Vairamuthu, S. (2020) Retrospective studies on tumor conditions in dogs over a period of four years (2014-2018) The Pharma Innovation J., 9(4): 224-227.

Sorenmo, K. (2003) Canine mammary gland tumors. Vet. Clin. Small Anim. Pract. 33: 573-596.

Sorenmo, K.U., Shofer, F.S. and Goldschmidt, M.H. (2000) Effect of spaying and timing of spaying on the survival of dogs with mammary carcinoma. J. Vet. Internal Med. 14: 266-270.

Wey, N., Gutberlet, K., Kohn, B., Rudolph, R., Hoppen, H. O. and Brunnberg, L. (2000) Mammary tumours in the bitch: hormonal influence with emphasis on 17β-oestradiol and progesterone. Kleintierpraxis, 45(1): 19-31.

Submitted

2024-02-23

Published

2024-02-23

How to Cite

S. Sruthi, K.S. Prasanna, A.J.George, I.S Sajitha, S.N. Sudheesh, P.P. Varuna, & R. Bharathi. (2024). Mammary Tumors in dogs: Age, Breed, Gender, Rearing, and Diet Factors. The Indian Veterinary Journal, 101(2), 34-38. https://doi.org/10.62757/IVA.2024.101.2.34-38