Importance of Aflatoxins in Animal Feed
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Authors
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Kasturi Devi Kondampati
College of Veterinary Science, Mamnoor, Warangal PVNR Telangana Veterinary University
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Beesam Srinu
College of Veterinary Science, Mamnoor, Warangal PVNR Telangana Veterinary University
Keywords:
Aflatoxicosis, Aflatoxins B1, Aspergillus spp, Animal Health, DiagnosisAbstract
Aflatoxins are the secondary metabolic products produced from moulds which have negative impact on animal health and production upon consumption. Majority of poor and developing countries with poor regulation authority in food processing, storage and weather condition as well as with high level malnutrition in all species of animals are susceptible to aflatoxicosis. Food and feed like groundnuts, sesame seeds, maize, millet and rice contaminations by aflatoxins have been reported due to fungal infection during pre- and post-harvest conditions. Even a low concentration of aflatoxins is hazardous for human and livestock. Aflatoxin B1 is the most common mycotoxin in food and among the most potent genotoxic and carcinogenic aflatoxins. It is produced both by Aspergillus flavus and Aspergillus parasiticus. Aflatoxin M1 is a major metabolite of aflatoxin B1 in humans and animals, which may be present in milk from animals fed with aflatoxin B1 contaminated feed. For effective food safety and quality, it is essential for identification and quantification of aflatoxins in food and feeds is a major challenge. Therefore, developing feasible, sensitive and robust analytical methods is paramount for the identification and quantification of aflatoxins present in low concentrations in food and feed. Diagnostic aids like chromatographic techniques viz HPLC, TLC and immunochemical detection methods for detection of aflatoxins in feed samples. The present review provides insights into effects of aflatoxin exposure on animal health, public health significance of aflatoxicosis, detection methods, prevention and control methods.
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References
Anonymous, (2010) European Commission. Commission Regulation (EU) No 165/2010 of 26 February 2010 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards aflatoxins. Official Journal of the European Union, L50/8–L50/12.
Anonymous, (2019) U.S. Food and Drug Administration (FDA). Action Levels for Aflatoxins in Animal Food, Compliance Policy Guide. 2019.
Ashiq, S., (2015) Natural occurrence of mycotoxins in food and feed: Pakistan perspective. Comprehensive Reviews in Food Science and Food Safety 14(2) : 159–175.
Atherstone, C., Grace, D., Lindahl, J.F., Kang’ethe, E.K., and Nelson, F., (2016) Assessing the impact of aflatoxin consumption on animal health and productivity. African Journal of Food Agriculture and Nutrition Development 16(3) : 10949–10966. DOI https://doi.org/10.18697/ajfand.75.ILRI01.
Battilani, P., Formenti, S., Ramponi, C., and Rossi, V., (2011) Dynamic of water activity in maize hybrids is crucial for fumonisin contamination in kernels. Journal of Cereal Science 54 : 467–472. DOI 10.1016/j.jcs.2011.08.014.
Bennett, J.W., and Klich, M., (2003) Mycotoxins. Clinical Microbiology Reviews 16(3) : 497‒516.
Binder, E.M., Tan, L.M., Chin, L.J., Handl, J., and Richard, J., (2007) Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients. Animal Feed Science and Technology 137 : 265–282. DOI 10.1080/19393210.2011.589034.
De Ruyck, K., De Boevre, M., Huybrechts, I., and De Saeger, S., (2015) Dietary mycotoxins, co-exposure, and carcinogenesis in humans: Short review. Mutation Research 766 : 32–41.
Diekman, M.A., and Green, M.L., (1992) Mycotoxins and reproduction in domestic livestock. Journal of Animal Science 70(5) : 1615‒1627.
Fink-Gremmels, J., (2008) The role of mycotoxins in the health and performance of dairy cows. Veterinary Journal 176 : 84–92.
Fung, F., and Clark, R.F., (2004) Health effects of mycotoxins: a toxicological overview. Journal of Clinical Toxicology 42 : 217–234. DOI 10.1081/clt-120030947.
Grace, D., (2013) Animals and aflatoxins. In: Unnevehr, L., Grace, D. (Eds.). Finding Solutions for Improved Food Safety. International Food Policy Research Institute, 1–2.
Gupta, R.C., (2007) Basic and Clinical Principles of Veterinary Toxicology. Elsevier, New York, 939–1018.
Hussein, H.S., and Brasel, J.M., (2001) Toxicity, metabolism and impact of mycotoxins on humans and animals. Toxicology 167(2) : 101–134.
Iqbal, S.Z., Jinap, S., Pirouz, A.A., and Faizal, A.R.A., (2015) Aflatoxin M1 in milk and dairy products, occurrence and recent challenges: A review. Trends in Food Science and Technology 46 : 110–119. DOI 10.1016/j.tifs.2015.08.005.
Jiang, Y., Hansen, P.J., Xiao, Y., Amaral, T.F., Vyas, D., and Adesogan, A.T., (2019) Aflatoxin compromises development of the preimplantation bovine embryo through mechanisms independent of reactive oxygen production. Journal of Dairy Science 102 : 10506–10513.
Jonathan, S.G., and Esho, E.O., (2010) Fungi and aflatoxin detection in two oyster mushrooms Pleurotusostreatus and Pleurotuspulmonarius from Nigeria. Electronic Journal of Environmental, Agricultural and Food Chemistry 9(11) : 1722–1730.
Khlangwiset, P., Shephard, G.S., and Wu, F., (2011) Aflatoxins and growth impairment: A review. Critical Reviews in Toxicology 41(9) : 740–755.
Komsky-Elbaz, A., Saktsier, M., and Roth, Z., (2018) Aflatoxin B1 impairs sperm quality and fertilization competence. Toxicology 393 : 42–50.
Kumar, P., Mahato, D.K., Kamle, M., Mohanta, T.K., and Kang, S.G., (2017) Aflatoxins: a global concern for food safety, human health and their management. Frontiers in Microbiology 7 : 2170. DOI 10.3389/fmicb.2016.02170.
Liu, N., Wang, J., Deng, Q., Gu, K., and Wang, J., (2018) Detoxification of aflatoxin B1 by lactic acid bacteria and hydrated sodium calcium aluminosilicate in broiler chickens. Livestock Science 208 : 28–32.
Magan, N., and Aldred, D. (2007) Post-harvest control strategies: minimizing mycotoxins in the food chain. International Journal of Food Microbiology 119 : 131–139.
Mutegi, C.K., Ngugi, H.K., Hendriks, S.L., and Jones, R.B., (2009) Prevalence and factors associated with aflatoxin contamination of peanuts from Western Kenya. International Journal of Food Microbiology 130 : 27–34. DOI 10.1016/j.ijfoodmicro.2008. 12.030.
Perrone, G., Haidukowski, M., Stea, G., Epifani, F., Bandyopadhyay, R., and Leslie, J.F., (2014) Population structure and Aflatoxin production by Aspergillus Sect. Flavi from maize in Nigeria and Ghana. Food Microbiology 41 : 52–59. DOI 10.1016/j.fm.2013.12.005.
Reddy, K.R.N., Salleh, B., Saad, B., Abbas, H.K., Abel, C.A., and Shier, W.T., (2010) An overview of mycotoxin contamination in foods and its implications for human health. Toxin Reviews 29 : 3–26. DOI 10.3109/15569541003598553.
Richard, J.L., (2007) Some major mycotoxins and their mycotoxicosis: An overview. International Journal of Food Microbiology 119(1‒2) : 3–10.
Sherif, S.O., Salama, E.E., and Abdel-Wahhab, M.A., (2009) Mycotoxins and child health: The need for health risk assessment. International Journal of Hygiene and Environmental Health. 212 : 347–368. DOI 10.1016/j.ijheh.2008.08.002.
Udomkun, P., Wiredu, A.N., Nagle, M., Müller, J., Vanlauwe, B., and Bandyopadhyay, R., (2017) Innovative technologies to manage aflatoxins in foods and feeds and the profitability of application- A review. Food Control 76 : 127–138. DOI 10.1016/j.foodcont.2017.01.008.
