Genomic Analysis of Antibiotic Related Genes of Morganellamorganii MS-27 iq
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Authors
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Moamin M.Khdir
Department of Biology, College of Science, University of Mosul, Mosul, Iraq
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Sahar S. Al-Nakkar
Department of Biology, College of Science, University of Mosul, Mosul, Iraq
Keywords:
M.morganii, genome sequencing, Urinary tract infectionsAbstract
The strain of Morganellamorganii MS-27 iq which was isolated from patient had urinary tract infection, in Mosul City (Iraq), has a genome size 3.91 Mb with GC content of 51.46%. This study investigate the antibiotic resistance of M. morganii MS-27 iq. Isolate appeared resistance to ampicillin, meropenem, imipenem, ceftriaxone, cefotaxime, cefixime, ciprofloxacin, and levofloxacin whereas sensetive to gentamycin and doxycycline. Genomic analysis of this strain showed, it had 8 genes related to antibiotic resistance mechanisms. 3 genes were related to antibiotic efflux pumps CRP, rsmA, andqacG. 3 genes were related to antibioticinactivation blaDHA-1, cat A2, fosA8. 2 genes were related to target alternation resistance mechanismsArn T andgyrB.
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References
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