Histopathology and Immunohistochemistry of an Atypical Case of Cutaneous Fibroma in a Crossbreed Cow - A Case Report
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Authors
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Siva, S
Department of Veterinary Pathology, Madras Veterinary College, Chennai - 600 007
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R. Sarangabani
Department of Veterinary Pathology, Madras Veterinary College, Chennai - 600 007
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Pazhanivel, N
Department of Veterinary Pathology, Madras Veterinary College, Chennai - 600 007
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Ganne Venkata Sudhakar Rao
Department of Veterinary Pathology, Madras Veterinary College, Chennai - 600 007
Keywords:
Crossbred cow, fibroma, pathology,special staining, immunohistochemistryAbstract
Fibroma is an uncommon benign neoplasm of mesenchymal origin in animals. It arises from any site containing connective tissue including dermal and subcutaneous fibroblast. A Five year old female crossbred Jersey cow was presented to the Veterinary Dispensary. The animal had a pedunculated soft mass in its pole region. The mass was removed successfully and sent for histopathological examination in 10% neutral buffered formalin. Microscopical examination revealed a haphazard arrangement of neoplastic spindle-shaped fibrocytes, elongated to oval-shaped nuclei with indistinct eosinophilic cytoplasm, and stray mitotic figures were seen. Special staining with picrosirius red revealed positive red-coloured neoplastic fibrocytes. Immunohistochemistry examination with a vimentin marker showed a positive brown-coloured cytoplasmic reaction. Based on the gross, histopathological, special staining, and immunohistochemistry, the tumor mass was confirmed as a cutaneous fibroma.
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- 2025-12-27 (2)
- 2024-04-25 (1)