Prednisolone-induced cholelithiasis in a Siberian Husky Dog
41 / 7
Authors
-
Biju P.Habeeb
-
A.Janus
-
Lekshmi, M.R.
-
N.Madhavan Unny
-
P.Vinu David
-
P.T.Dinesh
Keywords:
Prednisolone, cholelithiasis, ursodeoxycholic acidAbstract
A one-year-old male Siberian Husky dog affected with mixed species of Babesia gibsoni and Babesia canisvogeli infection developed cholelithiasis after prednisolone therapy. Initially, gallbladder sludge was observed on hepatic ultrasonography, which progressed into cholelith during the course of treatment. Upon discontinuation of steroid therapy and the inclusion of ursodeoxycholic acid and taurine supplements in the treatment regimen,a significant reduction in the size of the cholelithwas observed.
Downloads
References
Allan, F., McCallum, K.E., Genain, M.A., Harris, B.J. and Watson, P.J. (2020). Dissolution of cholelithiasis in a Cavalier King Charles Spaniel receiving conservative management with ursodeoxycholic acid. Vet. Rec. Case Reports. 8(3): e001206. Allan, F., Watson, P.J. and McCallum, K.E. (2021) Clinical features and outcomes in 38 dogs with cholelithiasis receiving conservative or surgical management. J. Vet. Intern Med. 35(6): 2730-2742. Atalan, Gultekin, Barr, F.J. and Holt, P.E. (2007) Estimation of the volume of the gall bladder of 32 dogs from linear ultrasonographic measurements. Vet. Rec. 160(4): 118-122. Barrett, E. (2020) Imaging in hepatobiliary disease. Clinical Small Animal Internal Medicine. 659-675. Bexfield, N. and Watson, P. (2009) Treatment of canine liver disease: 1. drugs and dietary management. In practice. 31(3): 130-135. Center, S.A. (2009). Diseases of the gallbladder and biliary tree. Vet. Clin. Small Anim. Pract. 39(3): 543-598. Johnson, S.E. and Sherding, R.G. (2006) Diseases of the liver and biliary tract. Saunders manual of small animal practice (3rd edition), St. Louis, Missouri, 747. Kanemoto, H., Fukushima, K., Tsujimoto, H. and Ohno, K. (2017) Intrahepatic cholelithiasis in dogs and cats: a case series. Can. Vet. J. 58(9). 971. Larson, M.M. (2016) Ultrasound imaging of the hepatobiliary system and pancreas. Vet Clin North Am Small Anim Pract. 46(3): 453-80. Mehler, S.J. and Bennett, R.A. (2006) Canine extrahepatic biliary tract disease and surgery. Compend. Contin. Educ. Pract. Vet.28(4): 302. Nagahara, T., Ohno, K., Kanemoto, H., Kakimoto, T., Fukushima, K., Goto-Koshino, Y. and Tsujimoto, H. (2018) Effect of prednisolone administration on gallbladder emptying rate and gallbladder bile composition in dogs. Am. J. Vet. Res. 79(10): 1050-1056. Ramstedt, K.L., Center, S.A., Randolph, J.F., Yeager, A.E., Erb, H.N. and Warner, K.L. (2008) Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. Am. J. Vet. Res. 69(5): 647-651. Ward, P.M., Brown, K., Hammond, G., Parkin, T., Bouyssou, S., Coia, M., Nurra, G. and Ridyard, A.E. (2020) Cholelithiasis in the dog: prevalence, clinical presentation, and outcome. J. Am. Anim. Hosp. Ass. 56(3): 152. Yarimagan, H.S. and Bor, N.M. (1986) Changes of bile lipid composition induced by methylprednisolone. Biochem. Med. Metabolic Biol. 35(1): 7-11. Yogeshpriya, S., Selvaraj, P., Sivakumar, M., Venkatesan, M. and Veeraselvam, M. (2017) Intravenous clindamycin in the management of babesia gibsoni in a labrador with concurrent cholecystitis. Indian J. Vet. Med. 37(1&2): 80-81.
Downloads
Submitted
Published
Versions
- 2026-03-06 (4)
- 2026-03-06 (3)
- 2026-03-06 (2)
- 2026-01-29 (1)