Gastric Pylorus Gland Adenoma in a Pug: A Case Report


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Authors

  • Sachin Chaudhary
  • Vikas Jaiswal
  • Aarti Bhatele
  • Surbhi K.Tyagi
  • Vivak Malik

https://doi.org/10.62757/11rsvn12

Keywords:

Pug, Pylorus, Adenoma

Abstract

A 1.5-year-old female Pug with a history of chronic intermittent vomiting revealed multiple polypoid growths in the pyloric region of the stomach on endoscopic examination. Cytology revealed the presence of cohesive cells with a round nucleus and prominent nucleoli, coarse chromatin material. The masses were removed by open surgery, and samples were processed for histopathology, which showed multiple layers of atypical epithelial cells exhibiting areas of malignancy and the absence of an apical mucin cap. Alkaline phosphatase was the only hemato-biochemical parameter found to be increased significantly. Based on the above findings, the case has been concluded as a pyloric gland adenoma.

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References

Bertz, S., M.Angeloni, J.Drgac, C.Falkeis, C.Lang-Schwarz, W.Sterlacci, L.Veits, A.Hartmann and M.Vieth (2021), Helicobacter infection and gastric adenoma, Microorganisms, 9: 108.

Castro, R., P.Pimentel-Nunes and M.Dinis-Ribeiro (2017), Evaluation and management of gastric epithelial polyps, Best Practice and Research Clinical Gastroenterology, 31: 381-87.

Hackeng, W.M., E.A.Montgomery, F.M.Giardiello, A.D.Singhi, M.Debeljak, J.R.Eshleman and L.A.A.Brosens (2016), Morphology and genetics of pyloric gland adenomas in familial adenomatous polyposis, Histopathology, 70: 549–57.

Kim, K., B.Jun, S.Han, D.Kim, H.Kim, H.Kim, S.Do, J.Kim, H.Kim and S.Yang (2022), Gastric Hyperplastic Polyp Causing Upper Gastrointestinal Hemorrhage and Severe Anemia in a Dog, Vet. Sci., 9: 680.

Kitagawa, D., T.Yamasaki, T.Ikeda, Y.Sakata, N.Hirata, T.Suekane and H.Nebiki (2023), A case of pyloric gland adenoma with high-grade dysplasia in the duodenum arising from heterotopic gastric mucosa observed over 5 years, Clinical Journal of Gastroenterology, 16: 26-31.

Lev, R. and W.C.Griffiths (1982). Colonic and small intestinal alkaline phosphatase: a histochemical and biochemical study, Gastroenterology, 82: 1427-35.

Luna, L.G. (1968). Manual of histological staining methods of the Armed Forces Institute of Pathology. 3rd ed. New York: McGraw-Hill Book Company. Pp 33.

Pezhouh, M.K. and J.Y.Park (2015), Gastric Pyloric Gland Adenoma. Archives of Pathology and Laboratory Medicine, 139: 823–26.

Shafiuzama, M., S.Babu, M.S.Krishnaveni, T.N.Ganesh and S.Hemalatha (2015), A Report of Gastric Adenocarcinoma in a Dog, Inte. J. Advanced Vet. Sci. and Tech., 4(1): 191-94.

Taulescu, M.A., B.A.Valentine, I.Amorim, F.Gärtner, D.L.Dumitraşcu, A.F.Gal, B.Sevastre and C.Catoi (2014), Histopathological features of canine spontaneous non-neoplastic gastric polyps - a retrospective study of 15 cases, Histology and Histopathology, 29: 65–75.

Tanaka, T., Y,Wada S.Noguchi , H.Nishida, H.Akiyoshi (2023), Contrast-enhanced CT features of pyloric lesions in 17 dogs: Case series, Vet. Radiol. Ultrasound, 64: 262–70.

Vieth, M., R.Kushima, F.Borchard and M.Stolte (2003), Pyloric gland adenoma: a clinico-pathological analysis of 90 cases, Virchows Archiv., 442: 317–21.

Watanabe, H., H.Tokuyama, H.Ohta, Y.Satomura, T.Okai, A.Ooi and N.Sawabu (1990), Expression of placental alkaline phosphatase in gastric and colorectal cancers: an immunohistochemical study using the prepared monoclonal antibody, Cancer, 66: 2575-82.

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Submitted

2026-03-27

Published

2026-03-27

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Articles

How to Cite

Sachin Chaudhary, Vikas Jaiswal, Aarti Bhatele, Surbhi K.Tyagi, & Vivak Malik. (2026). Gastric Pylorus Gland Adenoma in a Pug: A Case Report. The Indian Veterinary Journal, 102(6). https://doi.org/10.62757/11rsvn12