Ivermectin, its Applications in Aquaculture and Detection Methods

Ivermectin, Applications and Detection Techniques

Abstract

Aquaculture is one of the fastest-growing food producing sectors worldwide. However, diseases remain a significant challenge for sustainable aquaculture production. Parasitic infestations, particularly in freshwater fishes, are causing economic losses to farmers. Chemotherapeutants are used for direct treatment of these infestations in aquaculture farms. Ivermectin (IVM) is a macrocyclic lactone in the avermectin group, which is used to treat parasitic infections in humans and farmed animals. It is administered orally and is successfully used to treat  parasitic infestations due to its effect on glutamate-gated chloride channels (GluCls). This review paper discusses Ivermectin of discovery, structure, mechanism of action, applications in aquaculture, and detection methods, focusing on its impact and policy implications in the aquaculture sector.