Leaching and Residual Kinetics of Oxytetracycline Incorporated Feed Treated to Juvenile Black Tiger Shrimp Penaeus monodon fabricious

Abstract

The leaching rate of oxytetracycline (OTC)incorporated medicated feed after immersion in water was high during the first 10 min. About 56% of loss of OTC from the medicated feed was observed after 2 h of immersion, the leaching rate was not uniform in the 10 h experiment period. Juvenile black tiger shrimp Penaeus monodon fed for 7 days with 50-100 mg/kg shrimp of OTC were examined for residual accumulation and depletion. A residue of 3.47vig/g shrimp tissue was found after 1 day of post dosing. This concentration was estimated as 0.77% of the total OTC intake in the 7 days of experimental period. A substantial quantity of residue (1.56 ng/g) was observed up to 15 days of post-treatment. By the 20,h day of treatment, the OTC concentration was found in trace quantity (0.42 pg/g) or below detectable limit.