EFFECT OF PHOSPHAMIDON ON HEPATIC AND RENAL CATALASE OF A FRESHWATER BONY FISH


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Authors

  • P C Thomas Orissa University of Agriculture and Technology, Bhubaneswar.
  • T L Murthy Orissa University of Agriculture and Technology, Bhubaneswar.

Abstract

Invitro and invivo experiments were conducted to find out whether Phosphamidon
(Dimecron) — a widely used systemic organophosphate insecticide —
is having any effect on the catalase activity of liver and kidney of a freshwater
bony fish, Clarias batrachus. Results obtained from invivo experiments indicate
that catalase activity in liver and kidney are reduced remarkably by the action of
phosphamidon. Invivo inhibition of hepatic and renal calase are 30.9% and 28.5%
respectively. Studies on the invitro effect of phosphamidon (50^il|ml in the final
dilution) indicate 53.9% and 65.3% inhibitions of the enzyme activity in the liver
and kidney homogenates. It is concluded that phosphamidon is a partial inhibitor
of the enzyme catalase. There is no significant change in haemoglobin content of
blood from treated and control fishes.

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Author Biographies

  • P C Thomas, Orissa University of Agriculture and Technology, Bhubaneswar.
    Orissa University of Agriculture and Technology, Bhubaneswar.
  • T L Murthy, Orissa University of Agriculture and Technology, Bhubaneswar.
    Orissa University of Agriculture and Technology, Bhubaneswar.

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How to Cite

Thomas, P. C., & Murthy, T. L. (2011). EFFECT OF PHOSPHAMIDON ON HEPATIC AND RENAL CATALASE OF A FRESHWATER BONY FISH. Indian Journal of Fisheries, 21(2), 594-596. https://epubs.icar.org.in/index.php/IJF/article/view/12342