Mercury toxicity on differential distribution of dehydrogenases in various regions of the brain in L. rohita (Ham.)

Abstract

The sublethal effect of mercury on differential distribution of oxidative
enzymes (glucose - 6- phosphate dehydrogenase, NAD-isocitrate dehydrogenase,
NADP-isocitrate dehydrogenase) in different brain regions (cerebrum,
diencephalon, cerebellum, medulla oblongata) under acute, chronic and
detoxication studies were investigated in L. rohita. The highest rise in the
enzymes was in cerebrum (0 to 8 hrs) and the lowest in cerebellum (8 to 16
hrs) during acute studies. During chronic studies, maximum rise was in the
oxidative enzymes in cerebrum (0 to 15 days) and minimum in cerebellum
(evenly). In detoxication studies the fast fall in the oxidative enzymes was in
cerebellum (0 to 15 days) and slow fall in cerebrum (30 to 45 days).