A CASE REPORT OF CHRONIC HEPATITIS WITH EFFUSION IN A DOG AND ITS THERAPEUTIC MANAGEMENT
324 / 13
Keywords:
Abdominal Effusion, Alkaline phosphatase, chronic hepatitis, Hepatitis, dogAbstract
The present study was aimed to know the chronic hepatitis with abdominal effusion in a beagle dog and its therapeutic management. A 2.5 year old male beagle was presented to Madras Veterinary College teaching Hospital, madras veterinary college, Chennai with the history of inappetence, abdominal distension for past 10 days and the clinical signs of inappetence, fever and palpablelymph node and congested mucous membrane. On Physical examination, dog showed respiratory distress and dull. Dog was subjected for radiography examination, haematology, biochemistry parameters and ultrasound examination. On first day of examination, dog was treated with Lasix at the dose rate of 3 mg/kg body weight, antibiotics and Tribivet injection. Hematology and biochemical values revealed neutrophilia, elevated alkaline phosphatase, total bilirubin, direct bilirubin, and decreased total protein and albumin. The lateral view radiography of abdomen revealed fluid shadow and ultrasound examination revealed that chronic hepatitis with moderate abdominal effusion. In case of clinical suspicion of hepatitis an ultrasonographic liver scan can be of diagnostic aid and the finding of an altered structure can be indicative of a liver problem. In many cases of chronic hepatitis may not be associated with ultrasound abnormalities but ascites can be easily identified. Dog was treated with antibiotic cefotaxime at the dose rate of 25 mg/Kg body weight and Lasix at the dose rate of 3 mg/Kg body weight with liver supplement of Lysibin which contain silymarin and supplement with Astymin syrup for 3 weeks. The animal was reviewed after three weeks of treatment which was subjected for haeamtology, biochemistry and ultrasound examination which revealed there was improvement in the blood parameters with decreased total protein and normal level of Alkaline phosphatase and bilirubin level and ultrasound examination revealed normal study of abdominal effusion and liver echogenicity and dog had normal appetite and normal vital parameters. In this case hepatitis may be due to any viral etiology like adenovirus that may cause hepatitis with effusion that may be respond to treatment and diuretics and brought normal parameters of vital in dog. Chronic hepatitis with effusion may be further confirmed by Liver biopsy and molecular diagnosis.
Downloads
References
Ahmedullah, F., Akbor, M., Haider, G., Ossain, M.K., Hossain, A. and Shanta L. (2008). Pathological investigation of liver of the slaughtered buffaloes in Barisal District. Bangladesh Journal of Veterinary Medicine. 5(2): 81 – 85.
Boomkens, S.Y., Penning, L.C., Egberink, H.F., Van den Ingh, T.S.G.A.M. and Rothuizen, J. (2004). Hepatitis with special reference to dogs. A review on the pathogenesis and infectious etiologies, including unpublished results of recent own studies. Veterinary Quarterly, 26: 107-14.
Daniel, D. (2010). Continuing education in small animal common inflammatory liver diseases: Resident in small animal diagnostic imaging. Veterinary Ireland Journal, 6(11): 623-626
Erina, O. (2018). Difference between dogs and cats learn what makes each one special. Web site. http://erinollila.com//. Accessed on, June 9, 2012.
Gura, S. and Acarb, A. (2011). A retrospective investigation of canine adenovirus (CAV). Harold E. Anatomy of the Liver. 4th ed. London, UK: Elsevier.p 29
Hideyuki, K., Kenjiro, F., Hajime, T. and Koichi, O. (2017). Intrahepatic cholelithiasis dogs and cats. Canadian Veterinary Journal, 58(9): 971 - 973.
Hoffmann, G., Van den Ingh, T.S.G.A.M., Bode, P. and Rothuizen, J. (2006). Copper associated chronic hepatitis in labrador retrievers. Journal of Veterinary Internal Medicine, 20: 856 - 61.
Larson, M.M. (2007). The Liver and Spleen. Textbook of Veterinary Diagnostic Radiology. 5th ed. St. Louis, USA: Saunders. 667- 669.
Ming, H., Li, S., Tan, H.Y., Wang, N., Tsao, S.W. and Feng Y. (2015). Current status of herbal medicines in chronic liver disease therapy: The biological effects, molecular targets and future prospects. International Journal of Molecular Science, 29(35): 28705 - 45.
Pallavi, K., Sravani, D., Durga, P.N., Durga, S., Pavan, P.N., Babu, P.S. and Raviteja, K. (2017). Hepatitis: A review on current and future scenario. Journal of In Silico and In Vitro Pharmacology, 3(1): 15.
Pritt, S., Henderson, K.S. and Shek, W.R. (2010). Evaluation of available diagnostic methods for clostridium piliformein laboratory rabbits (Oryctolaguscuniculus). Journal of Laboratory Animals, 44: 14 – 19.
Sherman, S.C. and Tran, H. (2006). Pneumobilia: Benign or life-threatening. Journal of Emergency Medicine, 30(2): 147 - 153.
Spee, B., Arends, B., Van den Ingh, T.S.G.A.M., Penning, L.C. and Rothuizen, J. (2006). Copper metabolism and oxidative stress in chronic inflammatory and cholestatic liver diseases in dogs. Journal of Veterinary Internal Medicine, 20: 1085 - 92
Stockham, S.L. and Scott, M.A. (2008). Fundamentals of Veterinary Clinical Pathology. 2nd ed. Ames, Blackwel; 2008: 230.
Thapa, B.R. and Anuj, W. (2007). New diagnostic tests, liver function tests and their interpretation. Journal of Small Animal Medicine, 86(13): 560 - 569.
Van den Ingh, T.S.G.A.M., Van Winkle, T., Cullen, J.M., Charles, J.A. and Desmet, V.J. (2006). Morphological classification of parenchymal disorders of the canine and feline liver -2. Hepatocellular death, hepatitis and cirrhosis. In: WSAVA Standards for clinical and histological diagnosis of canine and feline liver diseases. Saunders Elsevier. p. 85-102
Downloads
Submitted
Published
Issue
Section
License
All the copy right belongs to the sponsoring Organization, Tamil Nadu Veterinary and Animal Sciences University, Chennai - 51.