Control of Penicillium citrinum growth and citrinin production by some polyamine biosynthesis inhibitors
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Authors
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P. GIRIDHAR, S.M. REDDY and M.V. RAJAM*
Mycotoxins Research Laboratory, Department of Botany, Kakatiya University, Warangal 506 009
*Deparment of Genetics, University of Delhi (South Campus), Delhi
Keywords:
Mycotoxin, citrinin, mycelial growth, inhibitor, polyamine, Penicillium citrinumAbstract
Polyamine biosynthesis inhibitors significantly inhibited citrinin production by P. citrinum. Both BCHA (cyclohexamine) and MGBG (methyl glyoxol bis) (guanyl hydrazone) at 7.5 mM completely inhibited citrinin production and reduced production by 97.5 and by 94% at 5.0 mM. DFMO (difluoromethyl ornithine) at 7.5 mM reduced mycelial growth of P. citrinum by 76% and citrinin production by 83%.
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