Evaluation of Isooxazoline derivatives in the Treatment of Canine Demodicosis


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Authors

  • Pardeep Sharma Department of Veterinary Medicine, Dr. GC Negi College of Veterinary and Animal Sciences CSK Himachal Pradesh Krishi Vishwavidyalaya Palampur, Himachal Pradesh-176062, India
  • Abhishek Bansal Department of Veterinary Medicine, Dr. GC Negi College of Veterinary and Animal Sciences CSK Himachal Pradesh Krishi Vishwavidyalaya Palampur, Himachal Pradesh-176062, India

Keywords:

afoxolaner, Demodex canis, fluralaner, sarolaner

Abstract

Canine demodicosis is a common dermatological condition observed indogs. The aim of this study was to evaluate the effectiveness of isooxazoline derivatives for the treatment of demodicosis compared to ivermectin.Forty-one dogs with demodicosis were treated with ivermectin (n=13), fluralaner(n=5), sarolaner(n=11) and afoxolaner (n=12),respectively. The mite count was evaluated on day 0, 28, 56 and 84 of treatment period. A single oral dose of isooxazoline derivatives reduced Demodex mite counts in skin scrapings by an average of 98.6% in all dogs by 28th day and 100% by 84th day. Single administration of ivermectin resulted to be only 76.8% effective. No adverse effects of drugs were observed in any of the dogs.

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References

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Submitted

2023-12-15

Published

2023-12-15

How to Cite

Pardeep Sharma, & Abhishek Bansal. (2023). Evaluation of Isooxazoline derivatives in the Treatment of Canine Demodicosis. The Indian Veterinary Journal, 100(12), 25-28. https://epubs.icar.org.in/index.php/IVJ/article/view/146481