Emergence of Quinolone Resistance in E. coli-associated Coliform Mastitis: A Case Report
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Authors
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Hima, K.M.
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A.Janus
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J.Alex
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P.M.Deepa
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R.L.Rathish
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P.Biju
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Hafeef
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E.A.Lali
Keywords:
Coliform mastitis, Quinolone resistance and mutationAbstract
A four-year-old Holstein Friesian crossbred cow with coliform mastitis showed poor response to enrofloxacin. Escherichia coli isolated from milk was multidrug resistant, with an enrofloxacin MIC >1024 µg/mL and QRDR mutations in gyrA (Ser83Leu and Asp87Asn) and parC (Ser80Ile). Gentamicin therapy resulted in complete recovery.
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References
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