An Overview on Dog Circovirus- A New Canine Pathogen
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Authors
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Deepika Thakur
CSKHPKV,Palampur
Keywords:
DogCV, hemorrhagic enteritis, vasculitis, co-infectionAbstract
Dog circovirus (DogCV) is a newly discovered mammalian circovirus (CV), and is the cause of various gastro-intestinal syndromes like diarrhea, vomiting and hemorrhagic enteritis/gastroenteritis in canines. DogCV was detected in various internal organs of domestic dogs and wild canids, indicating that DogCV prevalence is not only restricted to dogs but is also wide spread in wild canines. Recent DogCV might acts on alimentary canal as a co-factor in disease outcome in canines with multiple infections and may not be detected alone but with other key enteric pathogens like canine parvovirus-2(CPV-2) and canine distemper virus (CDV). In spite of the prevalence of DogCV infection, its pathogenic role is still undetermined in domestic and wild canids. This review article aims to provide information about DogCV morphology, genomic organization, replication, pathogenesis, epidemiology and application of various diagnostic methods.
References
Alistair N. J. Scott, Andrea Beckett, Joan A. Smyth, Neris W. Ball, Vilmos Palya & Daniel Todd (2007)Serological diagnosis of goose circovirus infections, Avian Pathology, 35:6, 495-499.
Bexton, S.,Wiersma,L.C.,Getu,S.,etal.,2015. Detection of circovirus in foxes with meningo-encephalitis, United Kingdom, 2009–2013. Emerg. Infect. Dis.21(7), 1205–1208.
Biagini,P.,Bendinelli,M.,Hino,S.,Kakkola,L.,Mankertz,A.,Niel,C.,Okamoto,H.,Raidal,S.,Teo,C.G.,Todd,D.,2011.Circoviridae.In:King,A.M.Q.,Lefkowitz,E.,Adams,M.J.,Carstens,E.B.(Eds.),Virus Taxonomy : Ninth Report of the Inter- national Committee on Taxonomy of Viruses. Elsevier, Philadelphia, PA, pp. 343–349.
Blinkova, O.,Rosario, K., Li, L., Kapoor, A., Slikas, B., Bernardin, F., Breitbart, M., Delwart, E., 2009. Frequent detection of highly diverse variants of cardiovirus, cosavirus, bocavirus, and circovirus in sewage samples collected in the United States. J. Clin. Microbiol. 47, 3507–3513.
Cheung AK. 2012. Porcine circovirus: transcription and DNA replication. Virus Res. 164:46 – 53.
Rosario K, Duffy S, Breitbart M. 2009. Diverse circovirus-like genome architectures revealed by environmental metagenomics. J. Gen. Virol. 90: 2418–2424.
Decaro,N.,Martella,V.,Desario,C.,Lanave,G.,Circella,E.,Cavalli,A.,etal.,2014.Genomic characterization of a circovirus associated with fatal hemorrhagic enteritis in dog, Italy. Faurez,F.,Dory, D., Grasland, B. and Jestin, A., 2009. Replication of porcine circoviruses. Virology journal, 6(1), p.60.
Gordon M., Allan,. and Ellis, J.A., 2000. Porcine circoviruses: a review. Journal of Veterinary Diagnostic Investigation, 12(1), pp.3-14.
Kapoor,A.,Dubovi,E.J.,Henriquez-Rivera,J.A.,Lipkin,W.I.,2012.Complete genome sequence of the first canine circo virus .J. Virol. 86,7018.
Li, L.,Kapoor,A.,Slikas,B.,Bamidele,O.S.,Wang,C.,etal.,2010. Multiple diverse circoviruses infect farm animals and are commonly found in human and chimpanzee feces.J.Virol.84, 1674–1682.
Li, L.,McGraw,S.,Zhu,K.,Leutenegger,C.M.,Marks,S.L.,Kubiski,S.,etal.,2013. Circovirus in tissues of dogs with vasculitis and hemorrhage. Emerg.Infect. Dis. 19,534–541.
Meng, X.J., 2012. Spread like a wildfire—the omnipresence of porcine circovirus type 2 (PCV2) and its ever-expanding association with diseases in pigs. Virus Res. 164, 1–3.
Michaela Gentil, et al. Tierarztl Prax Ausg K Kleintiere Heimtiere.,2017. Prevalence of Dog circovirus in healthy and diarrhoeic dogs.19; 45(2):89-94.
Olvera, A., Sibila, M., Calsamiglia, M., Segalés, J. and Domingo, M., 2004. Comparison of porcine circovirus type 2 load in serum quantified by a real time PCR in postweaning multisystemic wasting syndrome and porcine dermatitis and nephropathy syndrome naturally affected pigs. Journal of virological methods, 117(1), pp.75-80.
Opriessnig, T.,Halbur,P.G.,2012.Concurrent infections are important for expression of porcine circovirus associated disease.VirusRes.164,20–32.
Pearodwong, P., Srisuwatanasagul, S., Teankum, K., Tantilertcharoen, R., Tummaruk, P., 2015. Prevalence of porcine circovirus-2 DNA-positive ovarian and uterine tissues in gilts culled due to reproductive disturbance in Thailand. Trop. Anim. Health Prod. 47, 833–840.
Segalés J. Porcine circovirus type 2 (PCV2) infections: clinical signs, pathology and laboratory diagnosis. Virus Res. 2012; 164:10–9.
Shin, M.K., Yoon, S.H., Kim, M.H., Lyoo, Y.S., Suh, S.W., Yoo, H.S., 2015. Assessing PCV2 antibodies
in field pigs vaccinatedwith different porcine circovirus 2 vaccines using two commercial ELISA systems. J. Vet. Sci. 16, 25–29.
Tarjan, J.L., Pénzes, J.J., Töth, R.P., Benko,M., 2014. First detection of circo-like sequences in amphibians and novel putative circoviruses in fishes. Acta Vet. Hung. 62, 134–144
Tischer I, Rasch R, Tochtermann G. 1974. Characterization of papovavirus and picornavirus-like particles
in permanent pig kidney cell lines. Zentralbl. Bakteriol. Orig. A 226:153–167.
Todd, D.,2004. Avian circovirus diseases: lessons for the study of PMWS.Vet. Microbiol. 98,169–174.
Van den Brand, J.M., van Leeuwen, M., Schapendonk, C.M., Simon, J.H., Haagmans, B.L., Osterhaus, A.D. and Smits, S.L., 2012. Metagenomic analysis of the viral flora of pine marten and European badger feces. Journal of virology, 86(4), pp.2360-2365.
Zaccaria, Guendalina; Malatesta, Daniela; Scipioni, Gabriella; Felice, Elisabetta Di; Campolo, Marco; Casaccia, Claudia; Savini, Giovanni; Sabatino, Daria Di; Lorusso, Alessio. 2016 "Circovirus in domestic and wild carnivores: An important opportunistic agent?". Virology. 490: 69–74.
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