Histological Studies on the Caecum of Postnatal Guinea Pigs (Cavia porcellus)
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Keywords:
Caecum, guinea pig, mucosal folds, postnatal age.Abstract
The present histological study was conducted on the caecum of guinea pigs at different postnatal age groups. Microscopically, the caecal wall was composed of four layers namely the tunica mucosa, tunica sub mucosa, tunica muscularis and tunica serosa. The shape of the mucosal folds in the epithelium was short and stout like in 0–2-week- old guinea pigs, whereas they appeared tongue shaped in remaining age groups. The Lamina propria was composed of loose connective tissue with Crypts of Lieberkuhn. The tunica submucosa was composed predominantly of collagen and reticular fibres, with few elastic fibres mainly around the walls of the blood vessels. The tunica muscularis com- prised an inner circular and an outer longitudinal muscular layer. The mean height and width of the mucosal folds, the height of the columnar epithelial cells and the thickness of the tunica muscularis increased progressively with advanc- ing age in all the age groups studied.
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References
Bancroft, J.D. and Gamble, M. 2003. Theory and Practice of Histological Tech- niques. 5th
edn.,.Churchill Livingstone, New York, pp.172-184
Bergman, R.A. and Afifi, A.K. 1974. Atlas of Microscopic Anatomy: A Companion to Histology and Neuroanatomy..W.B.
Saunders Company, Philadelphia and London, pp.87-90.
Bevelander, G. 1965. Essentials of Histology. 5th edn.C.V. Mosby Company, Saint Louis; Toppan Company Ltd., Tokyo, Japan, pp.132-145.
Calhoun, M.L. 1954. Microscopic Anatomy of the Digestive System of the Chicken. Iowa State College Press, Ames, Iowa, pp.86-98.
Copenhaver, W.M., Bunge, R.P. and Bunge, M.B. 1975. Bailey’s Textbook of His- tology. 16th edn.. Williams and Wilkins Company, Baltimore, pp. 451–458.
Das, L.N. and Biswal, G. 1967. Microanatomy of intestine, pancreas and liver of the domestic duck (Anas boscas). Indian Veterinary Journal. 44(9): 763–766.
Dellmann, H.D. and Brown, E.M. 1987. Text- book of Veterinary Histology. Lea and Febiger, Philadelphia, pp.185–191.
Fitzgerald, T.L. 1969. The Coturnix Quail: Anatomy and Histology. Iowa State University Press, Ames, Iowa, pp.75- 89.
Frandson, R.D. and Whitten, E.H. 1981. Anatomy and Physiology of Farm Animals. 3rd edn., Lea and Febiger, Philadelphia, pp. 553.
Guo, Y., Bao, Y., Meng, Q., Hu, X., Ren, L.,Li, N. and Zhao, Y. 2012. Immunoglobulin genomics in the guinea pig (Cavia
porcellus). PLoS One. 7(6): e39298.
Humason, G.L. 1979. Animal Tissue Techniques. 2nd edn.W.H. Freeman and Company, London, pp. 56–76.
Kadam, S.D., Bhosle, N.S. and Kapadnis, P.J.2011. Comparative histological study of caecum
in cattle, sheep and goat. Indian Journal of Animal Research. 45(1): 67–69.
Kunzl, C. and Sachser, N. 1999. The behaviour- al endocrinology of domestication: A comparison between the domestic guinea pig (Cavia porcellus) and its wild ancestor. Hormones and Behavior. 35: 28–37.
Luna, L.G. 1968. Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology. 3rd edn.McGraw Hill Book Company, New York, pp.92-102.
Mohamed, A.A., Kadhim, K.H. and Hussein,D.M. 2018. Morphological and histological study of the caecum and colon in adult local Camelus dromedarius. Advances in Animal and Veterinary Sciences. 6(7): 286–291.
North, D. 1999. The guinea pig. In: Pool, T. (Ed.), The UFAW Handbook on the Care and Management of Laboratory Animals. 7th edn. Blackwell Science Ltd., London, pp. 367–388.
Nzalak, J.O., Onyeanusi, B.I., Samuel, A.O., Voh, A. and Ibe, C.S. 2011. Histological and histochemical studies of the colon in the African giant rat. Journal of Veterinary Anatomy. 4(1): 1–10.
Ozdemir, M., Crewe, K.H., Tucker, G.T. and Hodjegan, A.R. 2004. Assessment of in vivo CYP2D6 activity: Differential
sensitivity of commonly used probes to urine pH. Journal of Clinical Pharmacology. 44 : 1398–1404.
Pandit, K., Dhote, B.S., Mahanta, D., Sathapathy, S., Tamilselvan, S., Mrigesh, M.and Mishra, S. 2018. Gross and ultrastructural studies on the large intestine of Uttara fowl. International Journal of Current Microbiology and Applied Sciences. 7(3): 1464–1476.
Patt, D.I. and Patt, G.R. 1969. Comparative Vertebrate Histology. Smithsonian Institution Press, Washington, D.C, pp.
364–398.
Raja, K., Ushakumary, S., Ramesh, G., Ramesh, S., Rao, G.V.S. and Rajathi, S. 2022. Gross anatomical studies on the small intestine in the postnatal age groups of guinea pig. Haryana Veterinarian. 60(1): 1–4.
Snedecor, G.W. and Cochran, W.G. 1994. Statistical Methods. 6th edn., Oxford and IBH Publishing Co., Calcutta, India.pp 156-158.
Snipes, R.L. 1981. Anatomy of the caecum of the laboratory mouse and rat. Anatomy and Embryology. 162: 455–474.
Stinson, A.W. and Calhoun, M.L. 1981. Digestive system. In: Dellmann, H.D. and Brown, E.M. (Eds.), Textbook of Veterinary Histology. 2nd edn. Lea and Febiger,Philadelphia, pp. 203–258.
Trautmann, A. and Fiebiger, J. 1957. Fundamentals of the Histology of Domestic Animals. Comstock Publishing Associates, Ithaca, New York, pp. 153–229, 305.
Vigueras, R.M., Castañeda, J., Hernández, R., Reyes, G. and Álvarez, C. 1999. Histological characteristics of the
intestinal mucosa of the rat during the first year of life. Laboratory Animals. 33: 393–400.
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