Impact of IBDV Vaccination on Bursa of Fabricius in Rainbow Rooster Chickens: A Gross, Serological and Ultrastructural Analysis


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Authors

  • Monalish D Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Arup Kalita Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Kalita P C Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Prabal Jyoti Doley Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Rupan Sarkar Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Parimal Roychoudhury Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.
  • Mitnala Naveen Reddy Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Selesih, Aizawl, Mizoram, 796014.

Keywords:

Bursa of Fabricius, Rainbow Rooster, IBDV Vaccination, Gross, Serology, Ultrastructure

Abstract

This study aimed to evaluate the effects of IBDV vaccination on the gross morphology, serology, and ultrastructural integrity of the Bursa of Fabricius in Rainbow Rooster chickens from birth to 28 weeks of age. A total of 57 birds of both sexes were used. Blood samples (1 ml) were collected from the wing vein at 0, 4, 8, 12, 16, 20, 24, and 28 weeks for serological analysis. Ultrastructural studies were conducted on birds aged 8th and 12th weeks. Morphological observations revealed a progressive increase in body weight and bursal size, peaking at 12th weeks in both vaccinated and control groups before declining. The bursa appeared creamy white, soft, and oval to spherical. Length, width, and thickness significantly increased upto the 12th week. The maximum number of plicae was noted at the 4th weeks. Serologically, antibody titers peaked in vaccinated birds between weeks 12th and 16th, whereas titers in the control group were undetectable from week 8th onward. Ultrastructural analysis showed a well-defined cortex and medulla in bursal follicles, which are composed of reticular cells, lymphocytes, and macrophages.

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Submitted

2026-06-21

Published

2026-06-22

Issue

Vol. 37 No. 2 (2025): Indian Journal of Veterinary Anatomy 37(02), December 2025

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How to Cite

Monalish Debbarma, Arup Kalita, Pranab Chandra Kalita, Prabal Jyoti Doley, Rupan Sarkar, Parimal Roychoudhury, & Mitnala Naveen Reddy. (2026). Impact of IBDV Vaccination on Bursa of Fabricius in Rainbow Rooster Chickens: A Gross, Serological and Ultrastructural Analysis . Indian Journal of Veterinary Anatomy, 37(2), 149-155. https://epubs.icar.org.in/index.php/IJVA/article/view/180540