Histomorphological Studies on Prenatal Development of Ileal Peyer’s Patches in Buffalo

Abstract

The histomorphological studies on prenatal development of Peyer’s patches in ileum of 20 buffalo foetuses ranging from 11.5 cm CVRL (80 days) to 100 cm CVRL (full term) were conducted. The foetuses were categorized into three groups based on their curved crown rump length (CVRL). No typical Peyer’s patches were observed in ileum from 11.5 cm CVRL (80 days) to 33 cm CVRL (148 days). However, at 54 cm CVRL (195 days), the first primordial lymphoid follicle and dome was observed. At 70 cm CVRL (231 days), a number of developing lymphoid follicles were encountered. The interfollicular spaces began to develop at this stage. At 80 cm CVRL (254 days), dome of the follicles was prominent with subepithelial dome region (SED) or corona. Germinal centre (GC) was first observed at this stage. At 100 cm CVRL (full term), multiple layers of completely developed follicles were present with eminent dome, sub epithelial dome, diffuse interfollicular tissue and high endothelial venules.