Histological Studies on the Development of Cerebrum in Goat Foetuses

Abstract

Histogenesis of cerebrum was studied using 52 goat foetuses ranging from 1.4cm CRL (24 days of gestation) to 41.5cm CRL (full term). Standard procedures were adopted for histoarchitectural studies. At 24 days (1.4cm CRL), wall of the developing telencephalon showed an inner ependymal, middle mantle and outer marginal layers. Towards the middle of 2nd month, neuroblasts and spongioblasts of the inner ependymal layer of the cerebral wall migrated outwards giving rise to a superficial gray cortex. By 48 days, this cortical plate showed outer molecular and inner cellular layers. By 76 days, the cortex revealed four layers, viz., outer molecular, superficial granular, intermediate granular and deep granular layers. Cortical migration came to an end by about 12 weeks and the cells were undergoing differentiation during the 4th month. During 5th month, the neocortex was divided into six layers. Cortex was thicker at the top of the gyrus and the mean thickness decreased from 4th to 5th month.