Flow Cytometric Evaluation of T-Cell Subsets in Thymus of Nandanam Layer Chickens (Gallus domesticus)


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Authors

  • T. A. Kannan
  • Geetha Ramesh
  • S. Ushakumary
  • G. Dhinakarraj
  • S. Vairamuthu
  • A. Raja

Keywords:

T-cell subset, Thymus, Nandanam chicken

Abstract

Flowcytometric analysis revealed the presence of CD4 and CD8 positive thymocytes in the thymus of the different age groups of birds studied. The distribution pattern of CD4 and CD8 cells in thymus was different between the age groups studied. However, in all the age groups, CD4 cells were higher than CD8 cells which indicated the immune status of birds in different age groups in the present study. Similarly, the CD4 and CD8 ratio in thymus was increased from day-old (1.09) to forty weeks of age (1.56) which indicated the positive immune status of the birds in the present study.

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Author Biographies

  • T. A. Kannan

     Prof.; C SRM,  Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)

  • Geetha Ramesh
    Prof.; Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)
  • S. Ushakumary
    Prof.; Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)
  • G. Dhinakarraj
    Director, TRPVB; Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)
  • S. Vairamuthu
    Prof.; Central Clinical Laboratory; Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)
  • A. Raja
    Prof.; Deptt. Animal Biotechnology Department of Veterinary Anatomy, Madras Veterinary College Tamil Nadu Veterinary and Animal Sciences University, Chennai-600 007 (T.N.)

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How to Cite

Kannan, T. A., Ramesh, G., Ushakumary, S., Dhinakarraj, G., Vairamuthu, S., & Raja, A. (2016). Flow Cytometric Evaluation of T-Cell Subsets in Thymus of Nandanam Layer Chickens (Gallus domesticus). Indian Journal of Veterinary Anatomy, 28(1). https://epubs.icar.org.in/index.php/IJVA/article/view/59501