COMPARATIVE EVALUATION OF RESPIRATORY AND ANAESTHETIC PARAMETERS OF PROPOFOL AND ETOMIDATE FOR INDUCTION IN DEXMEDETOMIDINE- PENTAZOCINE-MIDAZOLAM PREMEDICATED CALVES FOR ABDOMINAL SURGERIES

V. Hemanth; K. Jayakumar; S. Senthil Kumar; K. Kannan; D. Vishnugurubaran

doi:10.56093/ijvasr.v55i4.181141

Authors

V. Hemanth M.V.Sc., Scholar, Department of Veterinary Surgery and Radiology, Veterinary College and Research Institute, TANUVAS, Orathanadu - 614 625. Thanjavur
K. Jayakumar Professor and Head, Department of Veterinary Surgery and Radiology, Veterinary College and Research Institute, TANUVAS, Orathanadu - 614 625. Thanjavur
S. Senthil Kumar Professor and Head, Department of Veterinary Surgery and Radiology, Veterinary College and Research Institute, TANUVAS, Salem - 636 112
K. Kannan Assistant Professor, Department of Veterinary Pharmacology and Toxicology, Veternary College and Research Institute, TANUVAS, Orathanadu - 614 625. Thanjavur
D. Vishnugurubaran Assistant Professor, Department of Veterinary Surgery and Radiology, Veterinary College and Research Institute, TANUVAS, Orathanadu - 614 625. Thanjavur

https://doi.org/10.56093/ijvasr.v55i4.181141

Keywords:

Dexmedetomidine, pentazocine, propofol, etomidate, modified oro- endotracheal tube

Abstract

Fourteen crossbred bovine calves presented to Veterinary Clinical Complex, VC&RI, Orathanadu with abdominal affections requiring surgical interventions were randomly divided into group I and group II with seven animals in each group. Dexmedetomidine, pentazocine and midazolam were given as premedication at the dose rate of 2 µg/kg body weight,1 mg/kg body weight and 0.2 mg/kg body weight intravenously, respectively.Induction of anaesthesia was performed with propofol at 2 mg/kg body weight and etomidate at 0.25 mg/kg body weight intravenously in group I and group II, respectively. All the calves were intubated using modified oro- endotracheal tubes and anaesthesia was maintained with isoflurane with variable vaporizer setting.Respiratory rate and anaesthetic parameters such as quality of sedation, induction, degree of muscle relaxation and recovery were assessed and recorded in both the groups. A significant decrease in the respiratory rate was noticed in group I animals, whereas group II animals showed a non-significant decrease in the respiratory rate after premedication, followed by a non-significant increase in respiratory rate at five minute of anaesthesia in both groups. The intubation and myoclonus scores were comparatively lower in group I than in group II animals. No significant difference was observed in the quality of recovery from anaesthesia between the groups. The anaesthetic parameters recorded in the present study concluded that propofol produced rapid anaesthetic induction and smooth recovery with ease of oroendotracheal intubation compared to etomidate in calves.

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