Biochemical Composition and Technological Applications of Cereal Bran: A Multisectoral Review

Cereal Bran: From Composition to Application

Abstract

Cereal bran, generated in large quantities during grain milling, has historically been regarded as a low-value byproduct and mainly directed toward animal feed or disposal. Increasing evidence regarding its rich compositional profile encompassing dietary fiber, high-quality proteins, lipids, essential micronutrients, and diverse bioactive phytochemicals has prompted renewed scientific and industrial interest. These constituents impart desirable functional properties and contribute therapeutic effects, including antioxidant, anti-inflammatory, hypolipidemic, and glycaemic-regulatory activities. Advances in processing and extraction technologies, particularly ultrasound-assisted, microwave-assisted, and enzyme-assisted methods, have enhanced the efficient recovery of bran-derived bioactives while reducing challenges associated with antinutritional factors and limited digestibility. Within the framework of a circular bioeconomy, the strategic valorization of cereal bran supports sustainable resource utilization, waste minimization, and the development of high-value products across food, nutraceutical, pharmaceutical, cosmetic, and biomaterial sectors. Therefore, cereal bran represents a renewable and multifunctional resource with strong potential to contribute to global nutrition, health promotion, and environmentally responsible industrial innovation.