PHYTOPHARMACOLOGICAL EVALUATION OF ANACARDIUM OCCIDENTALE L. TESTA FROM CASHEW PROCESSING BIOWASTE
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Keywords:
Anacardium occidentale L. testa, Anti-diabetic activity, Anti-inflammatory activity, Biowaste, IC50, values, PhytopharmacologyAbstract
The present study was performed during the year 2024 to evaluate and explore the phytopharmacological properties of Anacardium occidentale L. nut testa – a biowaste obtained after cashew kernel processing. The presence of versatile forms of phytochemicals was confirmed by qualitative analysis, whereas anti-nutritional factor analysis revealed no detectable presence.The total phenolic content was quantified, as phenols can contribute to various biological activities. The pharmacological properties of the testawere assessed using in-vitro alpha amylase inhibition assay and in-vitro protein denaturation assay. The former method was used to estimate the anti-diabetic potential and the resultant IC50 value of the standard and extract were 1.77±0.145µg/ml and 2.56 ±0.211µg/ml respectively. The latter method was opted to evaluate the anti-inflammatory potential of the extract. The IC50 values of the standard was 3.17 ±0.221 µg/mland the extract were 4.80 ±0.314 µg/ml. The results of the study showed that the sample contains substantial amounts of phenols, potentially contributing to the significant anti-diabetic and anti-inflammatory activity compared to that of the standards used.Thus, the study aids the research in utilizing cashew nut testa for developing value added products with pharmacological potential.
References
Bailey-Shaw, Y. A., Williams, L. A., Green, C.
E., Rodney, S. and Smith, A. M. 2017.
In-vitro evaluation of the anti
inflammatory potential of selected
Jamaican plant extracts using the bovine
serum albumin protein denaturation
assay. International Journal of
Pharmaceutical Sciences Review and
Research, 47(1),145-153.
de Paulo Farias, D., de Araujo, F. F., Neri-Numa,
I. A. and Pastore, G. M. 2021. Antidiabetic
potential of dietary polyphenols: A
mechanistic review. Food Research
International, 145, 110383.
Directorate of Cashew and Cocoa
development. Crop history, Cashew.
Retrieved from Crop history - cashew |
Directorate of Cashewnut and Cocoa
Development on 13.11.2024.
Kaur, N., Kumar, V., Nayak, S. K., Wadhwa, P.,
Kaur, P. and Sahu, S. K. 2021. Alpha
amylase as molecular target for
treatment of Diabetes mellitus: A
comprehensive review. Chemical biology
and drug design, 98(4), 539-560.
Kerala State Agency for the expansion of
Cashew Cultivation 2022. About cashew.
Retrieved from KSACC - Kerala State
Agency for the expansion of Cashew
Cultivation on 12. 11. 2024.
Samtiya, M., Aluko, R. E. and Dhewa, T. 2020.
Plant food anti-nutritional factors and
their reduction strategies: an
overview. Food Production, Processing
and Nutrition, 2, 1-14.
Sruthi, P. and Naidu, M. M. 2023. Cashew nut
(Anacardium occidentale L.) testa as a
potential source of bioactive compounds:
A review on its functional properties and
valorization. Food
Chemistry
Advances, 3, 100390.
Wickramaratne, M. N., Punchihewa, J. C. and
Wickramaratne, D. B. M. 2016. In-vitro
alpha amylase inhibitory activity of the
leaf extracts of Adenanthera pavonina.
BMC complementary and alternative
medicine, 16: 1-5.
Yahfoufi, N., Alsadi, N., Jambi, M. and Matar,
C. 2018. The immunomodulatory and
anti-inflammatory role of polyphenols.
Nutrient, 10(11): 1618.
Zafeer, M. K., and Bhat, K. S.2023. Valorisation
of agro-waste cashew nut husk (Testa)
for different value-added products.
Sustainable Chemistry for Climate
Action, 2, 100014
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