Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats


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Authors

  • K V Vishnu
  • K K Ajeesh Kumar
  • K K Asha
  • K R Remyakumari
  • B Ganesan
  • R Anandan
  • Niladri Sekhar Chatterjee
  • Suseela Mathew

https://doi.org/10.56093/ft.v52i4.53008

Keywords:

Bramble shark, liver oil, anti-inflammation, anti-ulcer

Abstract

Anti-inflammatory and anti-ulcer activities of
Bramble shark (Echinorhinus brucus) liver oil were
examined in rats. The oil showed significant
proportion of n-3 polyunsaturated fatty acids
(PUFAs), the percentages of EPA (eicosapentaenoic
acid) and DHA (docosahexaenoic acid) being 16 and
18% respectively. The study also revealed that liver
oil had a very favourable n3:n6 ratio of 4.7. Oral
administration of shark liver oil at 1g kg-1 concentration
significantly attenuated the formalin-induced
paw edema in experimental rats. It exerted
potent anti-ulcer effect against acid-ethanol mixturemediated
lesion formation in the rat gastric mucosa.

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Submitted

2015-10-31

Published

2025-05-23

How to Cite

Vishnu, K. V., Ajeesh Kumar, K. K., Asha, K. K., Remyakumari, K. R., Ganesan, B., Anandan, R., Chatterjee, N. S., & Mathew, S. (2025). Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats. Fishery Technology, 52(4), 252-257. https://doi.org/10.56093/ft.v52i4.53008
Citation