Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats
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Keywords:
Bramble shark, liver oil, anti-inflammation, anti-ulcerAbstract
Anti-inflammatory and anti-ulcer activities of
Bramble shark (Echinorhinus brucus) liver oil were
examined in rats. The oil showed significant
proportion of n-3 polyunsaturated fatty acids
(PUFAs), the percentages of EPA (eicosapentaenoic
acid) and DHA (docosahexaenoic acid) being 16 and
18% respectively. The study also revealed that liver
oil had a very favourable n3:n6 ratio of 4.7. Oral
administration of shark liver oil at 1g kg-1 concentration
significantly attenuated the formalin-induced
paw edema in experimental rats. It exerted
potent anti-ulcer effect against acid-ethanol mixturemediated
lesion formation in the rat gastric mucosa.
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Submitted
2015-10-31
Published
2025-05-23
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Copyright rests with the Society of Fisheries Technologists (India).How to Cite
Vishnu, K. V., Ajeesh Kumar, K. K., Asha, K. K., Remyakumari, K. R., Ganesan, B., Anandan, R., Chatterjee, N. S., & Mathew, S. (2025). Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats. Fishery Technology, 52(4), 252-257. https://doi.org/10.56093/ft.v52i4.53008