Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats
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Authors
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K V Vishnu
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K K Ajeesh Kumar
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K K Asha
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K R Remyakumari
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B Ganesan
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R Anandan
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Niladri Sekhar Chatterjee
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Suseela Mathew
Keywords:
Bramble shark, liver oil, anti-inflammation, anti-ulcerAbstract
Anti-inflammatory and anti-ulcer activities of
Bramble shark (Echinorhinus brucus) liver oil were
examined in rats. The oil showed significant
proportion of n-3 polyunsaturated fatty acids
(PUFAs), the percentages of EPA (eicosapentaenoic
acid) and DHA (docosahexaenoic acid) being 16 and
18% respectively. The study also revealed that liver
oil had a very favourable n3:n6 ratio of 4.7. Oral
administration of shark liver oil at 1g kg-1 concentration
significantly attenuated the formalin-induced
paw edema in experimental rats. It exerted
potent anti-ulcer effect against acid-ethanol mixturemediated
lesion formation in the rat gastric mucosa.
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How to Cite
Vishnu, K. V., Ajeesh Kumar, K. K., Asha, K. K., Remyakumari, K. R., Ganesan, B., Anandan, R., Chatterjee, N. S., & Mathew, S. (2015). Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats. Fishery Technology, 52(4), 252–257. Retrieved from https://epubs.icar.org.in/index.php/FT/article/view/53008
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