Oxidative stress and antioxidant activity in female dogs undergoing laparoscopic and open elective ovariectomy

Rajesh Kumar; ARCHANA  KUMARI; RAMESH TIWARY; RAJESH KUMAR; SHYAMAL KANTI GUHA

doi:10.56093/ijans.v92i7.102089

Authors

Rajesh Kumar Indian Veterinary Research Institute
ARCHANA KUMARI Bihar Veterinary College, Patna, Bihar 800 014 India
RAMESH TIWARY Bihar Veterinary College, Patna, Bihar 800 014 India
RAJESH KUMAR Bihar Veterinary College, Patna, Bihar 800 014 India
SHYAMAL KANTI GUHA Bihar Veterinary College, Patna, Bihar 800 014 India

https://doi.org/10.56093/ijans.v92i7.102089

Keywords:

Canine, Oxidative stress, Molondialdehyde, superoxide dismutase, Catalase, and Laparoscope

Abstract

The present study was carried out to evaluate the biomarkers of oxidative stress and antioxidant activity in female
dogs undergoing laparoscopic and open elective ovariectomy at Bihar Veterinary College, Patna in 2016-17.
Twenty healthy animals were randomly divided into four groups, viz. A, B, C and D consisting of 5 animals each. The
ovariectomy was performed through laparoscopy in Group A and Group B. Open elective ovariectomy procedure
was used in Group C and Group D. Evaluation of surgical techniques was done on the basis of biomarkers for
oxidative stress and antioxidant activity at Pre, Post and 4th day post surgery. The superoxide dismutase level on
day 4th in Group B showed significant difference with highest value followed by Groups A, C and D respectively.
The catalase levels on day 4th in Group B were significantly different from Groups A and D but not from Group C.
The values within the groups were significantly higher on day 4th as compared to pre and post intervals of time.
It can be concluded that less oxidative stress is induced during surgical procedure by laparoscopy as compared to
open laparotomy ovariectomy in canines.

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Author Biography

Rajesh Kumar, Indian Veterinary Research Institute

Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Bareilly, UP

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