Plasma heavy metals and their effect on oxidative stress parameters of buffaloes inhabiting Buddha Nallah area of Ludhiana district in Punjab


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Authors

  • RAVNEEK SINGH DHALIWAL College of Veterinary Science, GADVASU, Ludhiana, Punjab 141 004 India
  • SUSHMA CHHABRA College of Veterinary Science, GADVASU, Ludhiana, Punjab 141 004 India

https://doi.org/10.56093/ijans.v90i5.104630

Keywords:

Buffaloes, Heavy metals, Oxidative stress, Plasma

Abstract

In the present study, plasma lead, cadmium, arsenic and nickel concentrations and oxidative stress parameters in buffaloes residing near Buddha Nallah region were evaluated. Blood samples of 59 buffaloes were collected for the study and plasma was separated and analyzed for heavy metal levels and for oxidative stress parameters like reduced glutathione,malonyldialdehyde and superoxide dismutase. Significant increase in plasma heavy metal concentrations was recorded in the buffaloes of the region and significant decrease in GSH and SOD and significant increase in MDA levels were also recorded in the buffaloes of the region. Samples with higher levels of heavy metals depicted oxidative damage in the animals residing near Buddha Nallah area of the Ludhiana city.

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References

Aflanie I, Muhyi R and Suhartono E. 2015. Effect of heavy metal on malondialdehyde and advanced oxidation protein products concentration: A focus on arsenic, cadmium, and mercury. Journal of Medical and Bioengineering 4: 332–37. DOI: https://doi.org/10.12720/jomb.4.4.332-337

Agency for Toxic Substances and Disease Registry (ATSDR). 2008. Toxological profile for Cadmium. Draft for public comment. US Department of Health and Human Sevices. Atlanta, US.

Andjelkovic M, Djordjevic A B, Antonijevic E, Antonijevic B, Stanic M, Stevuljevic J, Kalimanovska V S, Jovanovic M, Boricic N, Wallace D and Bulat Z. 2019. Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney. International Journal of Environmental Research and Public Health 16: 274–95. DOI: https://doi.org/10.3390/ijerph16020274

Arslan H H, Aksu D S, Ozdemir S, Yavuz O, Or M E and UB Barutcu. 2011. Evaluation of the relationship of blood heavy metal, trace element levels and antioxidative metabolism in cattle which are living near the trunk roads. Kafkasuniversitesi Veteriner Fakultesi Dergisi 17 (Suppl A).

Beutler E, Duron O and Kelly B M. 1963. Improved method for the determination of blood glutathione. Journal of Laboratory and Clinical Medicine 61: 882–88.

Dhaliwal R S and Chhabra S. 2016. Effect of heavy metals on oxidative stress parameters of cattle inhabiting Buddha nallah area of Ludhiana district in Punjab. Journal of Veterinary Science and Technology 7(5). DOI: https://doi.org/10.4172/2157-7579.1000352

Dwivedi S K, Swarup D, Dey S and Patra R C. 2001. Lead poisoning in cattle and buffalo near primary lead-zinc smelter in India. Veterinary and Human Toxicology 43: 93–4.

Engwa G A, Ferdinand, Nwalo F N and Unachukwu M N. 2019. Mechanism and health effects of heavy metal toxicity in humans, pp 1–23. Poisoning in the Modern World-new Tricks For an Old Dog.(Ed.) Karcioglu O.ISBN

Gaafar H M A, Abou-Aiana R M, Ghanem G H A and Ali M A. 2005. Accumulation of some heavy metals and histological aspects of body tissues of growing Friesian calves fed poultry litter and corn silage. Egyptian Journal of Animal Production 42: 95. DOI: https://doi.org/10.21608/ejap.2005.93014

Gaafar H M A. 2008. Accumulation of some heavy metals in hair, plasma and milk of cattle and buffaloes grazing berseem or reed plants in Egypt. Egyptian Journal of Animal Production 45: 71–8. DOI: https://doi.org/10.21608/ejap.2008.93868

Gurer H and Ercal N. 2000. Can antioxidants be beneficial in the treatment of lead poisoning? Free Radical Biology and Medicine 29: 927–45. DOI: https://doi.org/10.1016/S0891-5849(00)00413-5

Jomova K and Valko M. 2011. Advances in metal-induced oxidative stress and human disease. Toxicology 283: 65–87. DOI: https://doi.org/10.1016/j.tox.2011.03.001

Kaminski P, Kurhalyuk N and Szady-Grad M. 2007. Heavy metalinduced oxidative stress and changes in physiological process of free radicals in blood of white strok (Ciconia ciconia) chicks in polluted areas. Polish Journal of Environmental Studies 16: 555–62.

Misra M, Rodriguez R E and Kasprzak K S. 1990. Nickel induced lipid peroxidation in rat: Correlation with nickel effect on antioxidant defence systems. Toxicology 64: 1–17. DOI: https://doi.org/10.1016/0300-483X(90)90095-X

Nishikimi M, Rao N A and Yagi K A.1972. The occurrence of superoxide anion in the molecule oxygen. Biochemical and Biophysical Research Communications 4: 12–19.

Ogabiela E E, Yebpella G G, Adesina O B, Udiba U U, Ade-Ajayi F A, Magomya A M, Hammuel C, Gandu I, Mmereole U J and Abdullahi M. 2011. Assessment of metals levels in cow blood from cow’s grazed around Zango, Zaria and Challawa industrial estate, Kano-Nigeria. Journal of Applied Environmental and Biological Sciences 1: 69–73. Patrick L. 2006. Lead toxicity part II: the role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity. Alternative Medicine Review 11: 114–27.

Placer Z A, Cushman L L and Johnson B C. 1966. Estimation of product of lipid peroxidation (malondialdehyde) in biochemical system. Annals of Clinical Biochemistry 16: 359– 64. DOI: https://doi.org/10.1016/0003-2697(66)90167-9

Puls R. 1994. Mineral Levels in Animal Health-Diagnostic Data, 2nd Ed. Sherpa International, Clearbrook, B C, Canada.

Rana T, Bera A K, Bhattacharya D, Das S, Pan D and Das S K. 2012. Chronic arsenicosis in goats with special reference to its exposure, excretion and deposition in an arsenic contaminated zone. Environmental Toxicology and Pharmacology 33: 372– 76. DOI: https://doi.org/10.1016/j.etap.2011.12.026

Roy D, Das T K and Vaswani S. 2013. Arsenic: it’s extent of pollution and toxicosis: An animal perspective. Veterinary World 6: 53–8. DOI: https://doi.org/10.5455/vetworld.2013.53-58

Sandhir R and Gill K D. 1995. Effect of lead on lipid peroxidation in liver of rats. Biological Trace Element Research 48: 91– 97. DOI: https://doi.org/10.1007/BF02789081

Shaikh Z A, Vu T T and Zaman K. 1999. Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. Toxicolgy and Applied Pharmacology 154: 256–63. DOI: https://doi.org/10.1006/taap.1998.8586

Shunthoo R. 2010. Studies on toxic and heavy metals in milk and water in Punjab and its public health significance. pp. 54–58.

Sikka R. 2003. ‘Influence of soil characteristics on available Pb& Cd & their accumulation by Brassica spp’. Ph.D. dissertation, Punjab Agriculture University Ludhiana, India

Singh S T. 2012. ‘Surveillance, clinico-biochemical and therapeutic studies on mineral imbalances in dairy animals of south western region of Punjab’. Ph. D. dissertation. Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana (Punjab).

Somasundaram J, Krishnasamy R and Savithri P. 2005. Biotransfer of heavy metals in Jersey cows. Indian Journal of Animal Sciences 75: 1257–60.

Tomza-Marciniak A, Pilarczyk B, Bakowska M, Pilarczyk R and Wojcik J. 2011. Heavy metals and other elements in serum of cattle from organic and conventional farms. Biological Trace Element Research 143: 863–70. DOI: https://doi.org/10.1007/s12011-010-8910-z

Uchida M, Teranishi H, Aoshima K, Katoh T, Kasuya M and Inadera H. 2004. Reduction of erythrocyte catalase and superoxide dismutase activities in male inhabitants of a cadmium-polluted area in Jinzu river basin, Japan. Toxicology Letters 151: 451–57. DOI: https://doi.org/10.1016/j.toxlet.2004.03.009

Wang J, Zhang H, Zhang T, Zhang R, Liu R and Chen Y. 2015. Molecular mechanism on cadmium-induced activity changes of catalase and superoxide dismutase. International Journal of Biological Macromolecules 77: 59–67 DOI: https://doi.org/10.1016/j.ijbiomac.2015.02.037

Yazar E, Altunok V and Erouglu T. 2006. Concentrations of some elements in blood serum of Angora goats. Medycyna Wet 62: 1249–51.

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2020-09-10

Published

2020-09-10

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How to Cite

DHALIWAL, R. S., & CHHABRA, S. (2020). Plasma heavy metals and their effect on oxidative stress parameters of buffaloes inhabiting Buddha Nallah area of Ludhiana district in Punjab. The Indian Journal of Animal Sciences, 90(5), 773-777. https://doi.org/10.56093/ijans.v90i5.104630
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