Antimicrobial susceptibility profiles of Mycoplasma mycoides subsp. capri field isolates from goats in India

ANUP N KALMEGH; ANBAZHAGAN S; RAJNEESH RANA; ZUNJAR B DUBAL; PALLAB CHAUDHURI

doi:10.56093/ijans.v90i8.109290

Authors

ANUP N KALMEGH ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh 243 122 India
ANBAZHAGAN S ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh 243 122 India
RAJNEESH RANA ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh 243 122 India
ZUNJAR B DUBAL ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh 243 122 India
PALLAB CHAUDHURI ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh 243 122 India

https://doi.org/10.56093/ijans.v90i8.109290

Keywords:

Antimicrobial susceptibility, Caprine pleuropneumonia, Indian isolates, Mycoplasma mycoides subsp capri

Abstract

Erythromycin and Tylosin (Macrolides) followed by Tetracycline and Doxycycline (Tetracyclines) are found to be the best drugs of choice, under in-vitro antibiotic sensitivity test conducted with Disc diffusion method for the 10 Indian Mmc isolates recovered from goats. These relevant antibiotics may be recommended for use under field conditions. Although we have to keep in mind the gene exchange in Mollicutes along with other mechanisms, which may lead to the variation in their sensitivity to antibiotics in coming time.

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References

Ali T, Rahman S, Zhang L, Shahid M, Zhang S, Liu G, Gao J and Han B. 2016. ESBL producing Escherichia coli from cows suffering mastitis in China contain clinical class 1 integrons with CTX-M linked to ISCR 1. Frontiers in Microbiology 7: 1931. DOI: https://doi.org/10.3389/fmicb.2016.01931

Al-Momani W, Abu-Basha E, Ayling R D, Nicholas R A J and Janakat S. 2006. The in vitro effect of six antimicrobials against Mycoplasma putrefaciens, Mycoplasma mycoides subsp. mycoides LC and Mycoplasma capricolum subsp. capricolum isolated from sheep and goats in Jordan. Tropical Animal Health and Production 38(1): 1–7. DOI: https://doi.org/10.1007/s11250-006-4334-3

Antunes N T, Tavío M M, Assunção P, Rosales R S, Aquili V, De la Fe C and Poveda J B. 2007. In vitro susceptibilities of field isolates of Mycoplasma mycoides subsp. mycoides large colony type to 15 antimicrobials. Veterinary Microbiology 119(1): 72– 75. DOI: https://doi.org/10.1016/j.vetmic.2006.08.013

Ayling R D, Bisgaard-Frantzen S, March J B and Godinho K. 2005. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides Small-Colony type to reduce contagious bovine pleuropneumonia infection. Antimicrobial Agents and Chemotherapy 49(12): 5162–65. DOI: https://doi.org/10.1128/AAC.49.12.5162-5165.2005

Bébéar C, Dupon M, Renaudin H and de Barbeyrac B. 1993. Potential improvements in therapeutic options for mycoplasmal respiratory infections. Clinical Infectious Diseases 17(Supplement_1): S202–07. DOI: https://doi.org/10.1093/clinids/17.Supplement_1.S202

Citti C and Blanchard A. 2013. Mycoplasmas and their host: emerging and re-emerging minimal pathogens. Trends in Microbiology 21(4): 196–203. DOI: https://doi.org/10.1016/j.tim.2013.01.003

CLSI. 2002. Development of in vitro susceptibility testing criteria and quality control parameters for veterinary antimicrobial agents. CLSI document, approved guideline. National Committee for Clinical Laboratory Standards.

Hotzel H, Sachse K and Pfützner H. 1996. A PCR scheme for differentiation of organisms belonging to the Mycoplasma mycoides cluster. Veterinary Microbiology 49(1–2): 31–43. DOI: https://doi.org/10.1016/0378-1135(95)00176-X

Kumar V, Rana R, Mehra S and Rout P K. 2013. Isolation and characterization of Mycoplasma mycoides subspecies capri from milk of natural goat mastitis cases. ISRN Veterinary Science. http: //dx.doi.org/10.1155/2013/593029 DOI: https://doi.org/10.1155/2013/593029

Nicholas R A J and Ayling R D. 2003. Mycoplasma bovis: disease, diagnosis, and control. Research in Veterinary Science 74(2): 105–112. DOI: https://doi.org/10.1016/S0034-5288(02)00155-8

OIE (2017). World Animal Health Information Database (WAHIS) Interface

Rana R, Mehra M, Kumar V, Kumar A and Vihan V. 2009. Seroprevalence of contagious caprine pleuropneumonia in goats using native M. mycoides subsp. capri isolates. Indian Veterinary Journal 86(2): 115–17.

Shah M K, Saddique U, Ahmad S, Hayat Y, Rahman S, Hassan M F and Ali T. 2017. Isolation rate and antimicrobial susceptibility profiles of Mycoplasma mycoides subspecies capri field isolates from sheep and goats in Pakistan. Small Ruminant Research 153: 118–22. DOI: https://doi.org/10.1016/j.smallrumres.2017.06.002

Taylor-Robinson D and Bebear C. 1997. Antibiotic susceptibilities of mycoplasmas and treatment of mycoplasmal infections. Journal of Antimicrobial Chemotherapy 40(5): 622–30. DOI: https://doi.org/10.1093/jac/40.5.622

Thiaucourt F, Manso-Silvan L, Salah W, Barbe V, Vacherie B, Jacob D and Sirand-Pugnet P. 2011. Mycoplasma mycoides, from “mycoides Small Colony” to “capri”. A microevolutionary perspective. BMC Genomics 12(1): 114. DOI: https://doi.org/10.1186/1471-2164-12-114

Van Kuppeveld F J, Van der Logt J T, Angulo A F, Van Zoest M J, Quint W G, Niesters H G, Galama J M and Melchers W J. 1992. Genus-and species-specific identification of mycoplasmas by 16S rRNA amplification. Applied Environment Microbiology 58 (8): 2606–15. DOI: https://doi.org/10.1128/aem.58.8.2606-2615.1992