Analysis of allelic pattern across milk trait genes in native cattle adapted to high altitude region of Leh-Ladakh

MONIKA SODHI; PREETI VERMA; VIJAY K BHARTI; PRABHAT KUMAR; ARUP GIRI; PARVESH K; DEEPAK GAGOI; ANKITA SHARMA; SANDEEP MANN; MANISHI MUKESH

doi:10.56093/ijans.v90i11.111509

Authors

MONIKA SODHI National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
PREETI VERMA DRDO-Defence Institute of High Altitude Research (DIHAR), Leh, Ladakh UT
VIJAY K BHARTI National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
PRABHAT KUMAR National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
ARUP GIRI National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
PARVESH K National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
DEEPAK GAGOI National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
ANKITA SHARMA National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
SANDEEP MANN National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India
MANISHI MUKESH National Bureau of Animal Genetic Resources, Karnal, Haryana 132 001 India

https://doi.org/10.56093/ijans.v90i11.111509

Keywords:

Candidate gene, Genetic polymorphism, High altitude, Ladakhi cattle, Leh-Ladakh, Milk trait

Abstract

Ladakhi, the native cattle from Ladakh region of India have developed over the years under natural selection and can survive well at extreme climatic conditions, viz. high altitude, huge barren lands, low temperature (â‰¤â€“20Â°C) and hypoxic conditions. Even at extreme survival conditions, this cattle provides around 2â€“5 kg of milk. This highly evolved germplasm might possess unique alleles or combinations of alleles, hence attempt was made to study the frequency of allelic variants at important candidate gene loci affecting dairy traits. The observed distribution pattern of allele frequencies were different from taurine but in accordance with other Indian native cattle breeds indicating maintenance of indicine characteristics and near absence of taurine influence/introgression effect on this naturally evolved germplasm. Further, variant E at Îº-CN locus and two novel variants at BTN-3 loci were also observed. The present findings helped to understand the unique Ladakhi cattle population with respect to polymorphism and distribution of various alleles in candidate genes related to milk traits.

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