Differential adaptation of metabolic inflammation between primiparous and multiparous Zebu cows during transition period

PRATIK RAMESH WANKHADE; Manimaran Ayyasamy; ARUMUGAM KUMARESAN; MUNIANDY SIVARAM; VEERASAMY SEJIAN; DURAISAMY RAJENDRAN

doi:10.56093/ijans.v92i7.118208

Authors

PRATIK RAMESH WANKHADE Research Scholar, Livestock Research Centre (LRC), Southern Regional Station (SRS), ICAR-National Dairy Research Institute (NDRI), Adugodi, Bengaluru-560 030, Karnataka, (India) http://orcid.org/0000-0001-6336-2701
Manimaran Ayyasamy Livestock Research Center, Southern Regional Station, ICAR-NDRI, Bengaluru, Karnataka, India http://orcid.org/0000-0001-9063-2711
ARUMUGAM KUMARESAN Principal Scientist, Theriogenology Laboratory, LRC, SRS, ICAR-NDRI, Adugodi, Bengaluru http://orcid.org/0000-0002-8061-3477
MUNIANDY SIVARAM Principal Scientist, Economics and Statistics Section, SRS, ICAR-NDRI, Adugodi, Bengaluru http://orcid.org/0000-0003-3520-5287
VEERASAMY SEJIAN Principal Scientist, Division of Animal Physiology, ICAR-National Institute of Animal Nutrition and Physiology (NIANP), Adugodi, Bengaluru - 560 030, Karnataka, (India) http://orcid.org/0000-0002-8224-4521
DURAISAMY RAJENDRAN Principal Scientist, Division of Animal Nutrition, ICAR-NIANP, Adugodi, Bengaluru http://orcid.org/0000-0001-6619-6155

https://doi.org/10.56093/ijans.v92i7.118208

Keywords:

Deoni cows, Inflammatory indicators, Metabolic indicators, Milk yield, Parity, Transition period.

Abstract

This study aimed to estimate the changes in the milk yield, milk fat, energy indicators [NEFA, BHBA, Dry Matter
Intake (DMI) and Body Condition Score (BCS)] and concentration of innate immune molecules (Haptoglobin: Hp,
Serum Amyloid A: SAA, TLR-4, TNF-α, IL-1β, IL-6, and IL-8), during the transition period in primiparous and
multiparous dual-purpose zebu (Deoni) cows. The blood sample was collected at weekly intervals during pre-partum (-21±2, -14±1, -7±1, d), date of calving (day 0), and postpartum period (3±1, 7±1, 14±1, 21±2 d) for estimation
of the above plasma variables using commercially available bovine specific ELISA kits. DMI and BCS during
the corresponding period were also recorded. Data were analyzed using a linear mixed model considering group,
time and their interaction as fixed effects. Group, time and their interaction had significant effect on DMI where
primiparous cows consumed higher DMI during early postpartum period as compared to multiparous cows. Group
alone had significant effect on milk yield, milk fat per cent and BHBA level while time alone influenced BCS.
The interaction of group and time had significant effects on plasma TLR-4 and IL-8 concentration. Group also
had significant effect on Hp and TNF-α levels. It was concluded that parity had significant effect on metabolic
and immune indicators where higher DMI during transition period resulted in more milk yield in primiparous than
multiparous indigenous (Deoni) cows.

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Author Biography

Manimaran Ayyasamy, Livestock Research Center, Southern Regional Station, ICAR-NDRI, Bengaluru, Karnataka, India

Senior Scientist,Â LRC, SRS, ICAR-NDRI, Adugodi, BengaluruÂ

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