Investigating whether microsatellites could influence the relative expression level of TLR4 gene in bursa of Rhode Island Red chicken

KRISHNAN JAGADEESAN; SANJEEV KUMAR; ABDUL RAHIM; A S YADAV; ANANTA KUMAR DAS

doi:10.56093/ijans.v92i8.122483

Authors

KRISHNAN JAGADEESAN Veterinary collage and Research Institute, Orathanadu, Tamil Nadu
SANJEEV KUMAR Central Avian Research Institute, Izatnagar
ABDUL RAHIM Central Sheep and Wool Research Institute
A S YADAV Central Avian Research Institute, Izatnagar
ANANTA KUMAR DAS West Bengal University of Animal and Fishery Sciences

https://doi.org/10.56093/ijans.v92i8.122483

Keywords:

Impact, Microsatellite genotypes, TLR4 gene expression, RIR Chicken

Abstract

TLR4 gene, vitally linked to resistance to infection with Salmonella enteric serovar Typhimurium in chickens, was chosen as a candidate gene for this investigation to assess the probable impact of microsatellite genotypes on relative expression of TLR4 gene. Our study documented variable expression level of TLR4 gene in tissue bursa of RIR chicken encoded with different microsatellite genotypes. The DD and CC genotypes of MCW0330 microsatellite demonstrated numerically higher mRNA expression than its AA, AC and BD genotypes. Therefore, The MCW0330 genotyping may predict TLR4 gene expression if confirmed by a thorough investigation taking a large number of samples and then would play an important role in host-pathogen genetics with respect to Salmonellosis in poultry.

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Author Biographies

KRISHNAN JAGADEESAN, Veterinary collage and Research Institute, Orathanadu, Tamil Nadu

Dept. of Animal Genetics and Breeding, Assistant Professor
SANJEEV KUMAR, Central Avian Research Institute, Izatnagar

Division of Avian Genetics and Breeding, Principal Scientist
ABDUL RAHIM, Central Sheep and Wool Research Institute

North Temperate Regional Station, Scientist
A S YADAV, Central Avian Research Institute, Izatnagar

Pricipal Scientist
ANANTA KUMAR DAS, West Bengal University of Animal and Fishery Sciences

Department of Animal Genetics and Breeding, F/O-VAS, Assistant Professor

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