Lysyl oxidase (LOX) expression in normal and metabolic stressed cumulus oocyte complexes and effect of a LOX-inhibitor on oocyte maturational competence and viability


144 / 110

Authors

  • S K TRIPATHI CAR- National Institute of Animal Nutrition and Physiology, Bengaluru, Karnataka 560 030 India
  • S NANDI ICAR- National Institute of Animal Nutrition and Physiology, Bengaluru, Karnataka 560 030 India
  • P S P GUPTA ICAR- National Institute of Animal Nutrition and Physiology, Bengaluru, Karnataka 560 030 India
  • S MONDAL ICAR- National Institute of Animal Nutrition and Physiology, Bengaluru, Karnataka 560 030 India

https://doi.org/10.56093/ijans.v92i4.124031

Keywords:

β-aminopropionitrile, COCs, Embryo development, LOX, LOX-inhibitor, Metabolic stressors

Downloads

Download data is not yet available.

References

Fang Y, Chang H, Cheng J, Klausen C, Leung P and Yang X. 2016. Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells. Reproduction 152(3): 205–13. DOI: https://doi.org/10.1530/REP-16-0144

Gupta P S P, Nandi S, Ravindranatha B M and Sarma P V. 2002. Trypan blue staining to differentiate live and dead buffalo oocytes and its effect on embryo development in vitro. Buffalo Journal 18: 321–30.

Harlow C R, Rae M, Davidson L, Trackman P C and Hillier S G. 2003. Lysyl Oxidase gene expression and enzyme activity in the rat ovary: Regulation by follicle-stimulating hormone, androgen, and transforming growth factor-β superfamily members in vitro. Endocrinology 144(1): 154–62. DOI: https://doi.org/10.1210/en.2002-220652

Jiang J, Xiong H, Cao M, Xia X, Sirard MA and Tsang BK.2010. Mural granulosa cell gene expression associated with oocyte developmental competence. Journal of Ovarian Research 3: 6. DOI: https://doi.org/10.1186/1757-2215-3-6

Kendall N R, Marsters P, Scaramuzzi R J and Campbell B K. 2003. Expression of lysyl oxidase and effect of copper chloride and ammonium tetrathiomolybdate on bovine ovarian follicle granulosa cells cultured in serum-free media. Reproduction 125: 657–65. DOI: https://doi.org/10.1530/rep.0.1250657

Kobayashi K, Yamashitu S and Hoshi H. 1994. Influence of epidermal growth factor and transforming growth factor-a on in vitro maturation of cumulus enclosed bovine oocytes in defined medium. Journal of Reproduction and Fertilty 100: 439. DOI: https://doi.org/10.1530/jrf.0.1000439

Langenau D M, Goetz F W and Roberts S B. 1999. The upregulation of messengerribonucleic acids during 17-alpha, 20-beta-dihydroxy-4-pregnen-3-one induced ovulation in the perch ovary. Journal of Molecular Endocrinology 23: 137–52. DOI: https://doi.org/10.1677/jme.0.0230137

Li W, Nellaiappan K, Strassmaier T, Graham L, Thomas K M and Kagan H M. 1997. Localization and activity of lysyl oxidase within nuclei of fibrogenic cells. Proceeding of the National Academy of Science of the USA 94: 12817–22. DOI: https://doi.org/10.1073/pnas.94.24.12817

Nandi S, Gupta P S P and Mondal S. 2016. Ammonia concentrations in different size classes of ovarian follicles of sheep (Ovis aries): Possible mechanisms of accumulation and its effect on oocyte and granulosa cell growth in vitro. Theriogenology 85: 678–87. DOI: https://doi.org/10.1016/j.theriogenology.2015.10.007

Nandi S, Tripathi S K, Gupta P S and Mondal S. 2017. Effect of metabolic stressors on survival and growth of in vitro cultured ovine preantral follicles and enclosed oocytes. Theriogenology 104: 80–86. DOI: https://doi.org/10.1016/j.theriogenology.2017.07.024

Nandi S, Tripathi S K, Gupta P S P and Mondal S. 2018. Nutritional and metabolic stressors on ovine oocyte development and granulosa cell functions in vitro. Cell stress and Chaperones 23: 357–71. DOI: https://doi.org/10.1007/s12192-017-0846-1

Saad F A, Torres M, Wang H and Graham L. 2010. Intracellular lysyl oxidase. Effect of a specific inhibitor on nuclear mass in proliferating cells. Biochemical and Biophysical Research Communications 396(4): 944–49. DOI: https://doi.org/10.1016/j.bbrc.2010.05.028

Slee R B, Hillier S G, Largue P, Harlow C R, Miele G and Clinton M. 2001. Differentiation-dependant expression of connective tissue growth factor and lysyl oxidase messenger ribonucleic acids in rat granulosa cells. Endocrinology 142: 1082–89. DOI: https://doi.org/10.1210/endo.142.3.7990

Smith-Mungo L I and Kagan H M. 1998. Lysyl oxidase: properties, regulation and multiple functions in biology. Matrix Biology 16387–98. DOI: https://doi.org/10.1016/S0945-053X(98)90012-9

Talukder M N S, Iqbal A, Khandoker M A M Y and Alam M Z. 2011. Collection grading and evaluation of cumulus-oocyte complexes for in vitro maturation in sheep. Bangladesh Veterinarian 28(1): 31 – 38. DOI: https://doi.org/10.3329/bvet.v28i1.8811

Tripathi S K, Nandi S, Gupta P S P and Modal S. 2018. Beneficial effect of lysyl oxidase on in vitro development of cultured ovine normal and metabolic stressed cumulus oocytes complexes. Indian Journal of Animal Sciences 88(9): 1041–43.

Downloads

Submitted

2022-05-18

Published

2022-05-24

Issue

Section

Articles

How to Cite

TRIPATHI, S. K. ., NANDI, . S. ., GUPTA, P. S. P. ., & MONDAL, S. . (2022). Lysyl oxidase (LOX) expression in normal and metabolic stressed cumulus oocyte complexes and effect of a LOX-inhibitor on oocyte maturational competence and viability. The Indian Journal of Animal Sciences, 92(4), 422-425. https://doi.org/10.56093/ijans.v92i4.124031
Citation