Association analysis of GHR gene polymorphism with growth traits in sheep

JUNYAN  BAI; JINGYUN  LI; LIANG  WANG; XINLE  WANG; ZHIHAO  DONG; YU  CHEN; YOUBING  YANG; XIAOPING  JIA; XU  WANG; XUEYAN  FU; XIANG  JI; LONGWEI  WANG

doi:10.56093/ijans.v92i4.124200

Authors

JUNYAN BAI Henan University of Science and Technology, Luoyang 471023, China
JINGYUN LI Henan University of Science and Technology, Luoyang 471023, China
LIANG WANG Henan University of Science and Technology, Luoyang 471023, China
XINLE WANG Henan University of Science and Technology, Luoyang 471023, China
ZHIHAO DONG Henan University of Science and Technology, Luoyang 471023, China
YU CHEN Henan University of Science and Technology, Luoyang 471023, China
YOUBING YANG Henan University of Science and Technology, Luoyang 471023, China
XIAOPING JIA Henan University of Science and Technology, Luoyang 471023, China
XU WANG Henan University of Science and Technology, Luoyang 471023, China
XUEYAN FU Henan University of Science and Technology, Luoyang 471023, China
XIANG JI Henan University of Science and Technology, Luoyang 471023, China
LONGWEI WANG Henan University of Science and Technology, Luoyang 471023, China

https://doi.org/10.56093/ijans.v92i4.124200

Keywords:

Association analysis, GHR gene, Growth traits, PCR-RFLP, Sheep

Abstract

In this study, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was employed to investigate the polymorphism of GHR gene and the correlations of polymorphic sites with growth traits. The results showed that GHR detected CC, CD and DD genotypes in the five sheep populations. GHR gene had the highest DD genotype frequencies in Yuxi fatty-tailed sheep, Dorper sheep, Henan large-tailed han sheep, Hu sheep and small-tailed han sheep, being 0.889, 0.784, 0.785, 0.529 and 0.750, respectively. The correlation analysis indicated that GHR gene had significant correlations with chest circumference and abdomen circumference of sheep

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