Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle

NIDHI  MISHRA; RASHMI  SINGH; RAJNEESH  SIROHI; BHASKAR  GANGULY; SHREYA  GUPTA; AKHIL KUMAR  GUPTA

doi:10.56093/ijans.v95i2.151036

Authors

NIDHI MISHRA U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)
RASHMI SINGH U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)
RAJNEESH SIROHI U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)
BHASKAR GANGULY Zenex Animal Health India Private Ltd.
SHREYA GUPTA Zenex Animal Health India Private Ltd.
AKHIL KUMAR GUPTA Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar

https://doi.org/10.56093/ijans.v95i2.151036

Keywords:

Cattle, Combined vaccine, Dairy, FMD, HS, Monovac, Polyherbal immunomodulator

Abstract

A polyherbal immunomodulator (restobal) was fed orally in dairy cattle (treatment group) to study its effect on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines. Serum antibody titres for all three FMD virus serotypes were protective (1.80 log₁₀ to 2.40 log₁₀) in treatment and control groups of vaccinated animals till 90 days of vaccination. Antibody titre did not differ significantly in control and treatment groups. Antibody titres ranging from 1.74 log₁₀ to 1.92 log₁₀ were observed for P. multocida and animals were protected on 90 days of vaccination in both control and treatment groups. The Restobal treated group was no different than the control group in antibody response to FMDV and P. multocida. Antibody response for FMDV was similar with FMD vaccine and FMD-HS-BQ vaccine.

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