Efficacy of Ceftiofur and Marbofloxacin in the treatment of staphylococcal endometritis in cross-bred cows

D  SENGUPTA; DEEPAK  KUMAR; C S  AZAD; S K  SHEETAL; SAVITA  KUMARI; SANJAY  KUMAR; KESHAV  KUMAR

doi:10.56093/ijans.v94i9.151793

Authors

D SENGUPTA Bihar Animal Sciences University, Patna, Bihar 800 014 India
DEEPAK KUMAR Bihar Animal Sciences University, Patna, Bihar 800 014 India
C S AZAD Bihar Animal Sciences University, Patna, Bihar 800 014 India
S K SHEETAL Bihar Animal Sciences University, Patna, Bihar 800 014 India
SAVITA KUMARI Bihar Animal Sciences University, Patna, Bihar 800 014 India
SANJAY KUMAR Bihar Animal Sciences University, Patna, Bihar 800 014 India
KESHAV KUMAR Bihar Animal Sciences University, Patna, Bihar 800 014 India

https://doi.org/10.56093/ijans.v94i9.151793

Keywords:

Ceftiofur, Cow, Endometritis, Marbofloxacin, Staphyoloccus sp.

Abstract

Endometritis and sub-clinical endometritis are considered important factors for conception failure and repeat breeding conditions. Intra-uterine antibiotics infusion is generally recommended as the choice of treatment for endometritis. This work was performed to test the efficacy of ceftiofur sodium and marbofloxacin in the treatment of endometritis in cross-bred cows caused by Staphylococcus sp. One hundred cows found positive for Staphylococcus sp. from culture of uterine contents were grouped into two groups (CEF and MARB) of fifty cows each. Group CEF was treated with 1 g ceftiofur sodium (Xceft^®, Alembic, India) intra-muscularly (IM) for five days and Group MARB was treated with 10% marbofloxacin (Marbomet^®, Intas, India) at the dose rate of 2 mg/kg body weight IM once daily for 5 days. Animal from MARB and CEF groups were inseminated on next observed estrus after treatment and the conception rate was 52% and 32% compared to 60% in healthy control group, the difference being highly significant. The study reported antibiotic marbofloxacin as better alternative choice for the treatment of endometritis caused by Staphylococcus sp. in cross-bred cows.

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