Impact of nano-Selenium on biochemical, antioxidant, immunological and histological parameters of broiler chickens during rainy season

V  DHAIGUDE; R K  SWAIN; K  SETHY; N  PANDA; S K  MISHRA; S  MAITY

doi:10.56093/ijans.v95i9.168921

Authors

V DHAIGUDE College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar, India
R K SWAIN College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar, India
K SETHY College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar, India
N PANDA College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar, India
S K MISHRA College of Veterinary Science and Animal Husbandry, OUAT, Bhubaneswar, India
S MAITY GIET University, Odisha, India

https://doi.org/10.56093/ijans.v95i9.168921

Keywords:

Antioxidant, Broiler, Immune response, Nano-Se, Rainy season

Abstract

Poultry sector supports economies of many nations, especially evolving ones, and provides a consistent and inexpensive protein. Nano-selenium is utilized to increase mineral availability, which aid in broiler growth and maintain their health. The current research was conducted to evaluate the impact of dietary nano-selenium supplement on immunological, haematological, biochemical and histological parameters on Vencobb broiler chicks during rainy season. Two hundred seventy numbers of one-day-old broiler chicks were split in nine groups at random, individually encompassing of three replicates with ten chicks. The control group (T1) was provided a basal diet, T2 received 0.3 mg/kg of inorganic selenium, T3, T4, T5, T6, T7, T8 and T9 received 0.0187, 0.0375, 0.075, 0.15, 0.30, 0.60 and 1.20 mg/kg of nano-selenium, respectively. The results revealed that nano-selenium had no significant (p>0.05) influence on haematological parameters except MCV (%) at third week and MCV (femtolitre) as well as MCHC (%) at the fifth week (p<0.05). No significant differences (p>0.05) were observed among the treatment groups in any of the measured biochemical markers. The glutathione and superoxide dismutase enzyme actions were significantly (p<0.05) higher in T6 than in other groups, but no difference in catalase and lipid peroxidase activities at 5^th week. Nano-Se supplementation significantly (p<0.05) increased both cellular and humoral immunity response, however the T6 group showed best result. Our findings revealed that supplementing broiler chickens with nano-Se (0.15 mg/ kg) could improve antioxidant activity, boost immunological response and no harmful effect in liver and renal tissues during rainy season.

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References

Abd El-Hack ME, El-Saadony MT, Shafi ME, Alshahrani OA, Saghir SA, Al-Wajeeh AS and Abdel-Moneim AME 2021. Prebiotics can restrict Salmonella populations in poultry: a review. Animal Biotechnol 1-10. https://doi.org/10.1080/1049 5398.2021.1883637

Abdel-Moneim AME, Shehata AM, Mohamed NG, Elbaz AM and Ibrahim NS 2022a. Synergistic effect of Spirulina platensis and selenium nanoparticles on growth performance, serum metabolites, immune responses, and antioxidant capacity of heat-stressed broiler chickens. Biological Trace Element Research 200(2): 768–779. https://doi.org/10.1007/s12011-021-02662-w

Abdel-Moneim AME, Shehata AM, Selim DA, El-Saadony MT, Mesalam NM and Saleh AA 2022b. Spirulina platensis and biosynthesized selenium nanoparticles improve performance, antioxidant status, humoral immunity and dietary and ileal microbial populations of heat-stressed broilers. Journal of Thermal Biology 104: 103195. https://doi.org/10.1016/j. jtherbio.2022.103195

Abdelnour S A, Alagawany M, Hashem N M, Farag M R, Alghamdi E S, Hassan F U and Attia Y A. 2021. Nanominerals: fabrication methods, benefits and hazards, and their applications in ruminants with special reference to selenium and zinc nanoparticles. Animals 11(7): 1916. https://doi. org/10.3390/ani11071916

Abo-Al-Ela H G, El-Kassas S, El-Naggar K, Abdo S E, Jahejo A R and Wakeel R A. 2021. Stress and immunity in poultry: light management and nanotechnology as effective immune enhancers to fight stress. Cell Stress & Chaperones 26(3):457-472. https://doi.org/10.1007/s12192-021-01204-6.

Aebi H (1984) Catalase in vitro. In Methods in enzymology (Vol. 105, pp. 121-126). Academic press. https://doi.org/10.1016/ S0076-6879(84)05016-3

Ahmadi M, Ahmadian A and Seidavi A R. 2018. Effect of different levels of nano-selenium on performance, blood parameters, immunity and carcass characteristics of broiler chickens. Poultry Science Journal 6(1): 99-108. https://doi.org/10.22069/psj.2018.13815.1276.

Akinyemi F and Adewole D. 2021. Environmental stress in chickens and the potential effectiveness of dietary vitamin supplementation. Front Animal Science 2:775311. https://doi. org/10.3389/fanim.2021.775311

Alian H A and Samy H M, Ibrahim M T, and Mahmoud M. 2020. Nanoselenium effect on growth performance, carcass traits, antioxidant activity, and immune status of broilers. Environmental Science and Pollution Research 27(31): 38607-38616. https://doi.org/10.1007/s11356-020-09952-1

Bami M K, Afsharmanesh M, Espahbodi M and Esmaeilzadeh E. 2022. Effects of dietary nano-selenium supplementation on broiler chicken performance, meat selenium content, intestinal microflora, intestinal morphology, and immune response. Journal of Trace Elements in Medicine and Biology 69: 126897. https://doi.org/10.1016/j.jtemb.2021.126897

Banakar P S, Kumar S, Vinay V V, Dixit S, Tyagi N and Tyagi A K. 2021. Supplementation of Aloe vera extract in lactating goats’ diet: effects on rumen fermentation efficiency, nutrient utilization, lactation performance, and antioxidant status. Tropical Animal Health and Production 53(5): 1-10. https://doi.org/10.1007/s11250-021- 02894-x.

Bień D, Michalczuk M, Łysek-Gładysińska M, Jóźwik A, Wieczorek A, Matuszewski A, Kinsner M and Konieczka P. 2023. Nano-sized selenium maintains performance and improves health status and antioxidant potential while not compromising ultrastructure of breast muscle and liver in chickens. Antioxidants 12(4):905. doi: 10.3390/ antiox12040905

BIS, Bureau of Indian Standards. 2007. Poultry Feeds Specification. (5thRevision), Manak Bhavan, 9, Bahadur Shah Zafar Marg, New Delhi-11 110002.

Bron PA, Van Baarlen P and Kleerebezem M 2012. Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nature Reviews Microbiology 10(1): 66-78. https://doi.org/10.1038/nrmicro2690

Cai S J, Wu C X, Gong L M, Song T, W u H and Zhang L Y. 2012. Effects of nano-selenium on performance, meat quality, immune function, oxidation resistance, and tissue selenium content in broilers. Poult Science 91: 2532–2539. https://doi.org/10.3382/ps.2012-02160

Chen Y, He H, Bi X, Zhang Y and Yin H. 2023. Effects of various selenium-enriched yeasts, selenomethionine, and nano-selenium on production performance, quality, and antioxidant capacity in laying hens. Poultry Science 103387. https://doi.org/10.1016/j.psj.2023.103387

da Silva ICM, Ribeiro AML, Canal CW, Vieira MDM, Pinheiro CC, Gonçalves T and Ledur VS. 2011. Effect of vitamin E levels on the cell-mediated immunity of broilers vaccinated against coccidiosis. Brazilian Journal of Poultry Science 13: 53-56. https://doi.org/10.1590/S1516-635X2011000100008

DAHDF (2019) Department of Animal Husbandry Dairying & Fisheries. New Delhi: Ministry of Fisheries, Animal Husbandry & Dairying.

Dalgaard T S, Briens M, Engberg R M and Lauridsen C (2018) The influence of selenium and selenoproteins on immune responses of poultry and pigs. Animal Feed Science and Technology 238: 73-83. https://doi.org/10.1016/j.anifeedsci.2018.01.020

Debata N R, Sethy K, Swain R K, Mishra S K, Panda N and Maity S. 2023. Supplementation of nano-selenium (SeNPs) improved growth, immunity, antioxidant enzyme activity, and selenium retention in broiler chicken during summer season. Tropical Animal Health and Production 55: 260. https://doi.org/10.1007/s11250-023-03678-1

Edelman A S, Sanchez P L, Robinson M E, Hochwald G M and Thorbecke G J. 1986. Primary and secondary wattle swelling response to phytohemagglutinin as a measure of immunocompetence in chickens. Avian Diseases 105-111. https://doi.org/10.2307/1590619

Eid S A, Alagmy G N, Gad S A, Nossieur H H and Megahed H M. 2023. Immunological and nutritional effects of selenium and nano-selenium on broiler chickens exposed to heat stress. Journal of Advanced Veterinary Research 13(6): 965-973. https://www.advetresearch.com/index.php/AVR/article/ view/1368

Elarabany NA. 2018. comparative study of some haematological and biochemical parameters between two species from the Anatidae family within migration season. JoBAZ 79: 31. https://doi.org/10.1186/s41936-018-0044-4

Gangadoo S, Dinev I, Willson NL, Moore RJ, Chapman J, Stanley D. 2020. Nanoparticles of selenium as high bioavailable and non-toxic supplement alternatives for broiler chickens. Environmental Science and Pollution Research 27(14): 16159-16166. https://doi.org/10.1007/s11356-020-07962-7

Hafez HM and Shehata AA. 2021. Turkey production and health: Current challenges. German Journal of Veterinary Research 1(1): 3-14. https://doi.org/10.51585/gjvr.2021.0002

Hosnedlova B, Kepinska M, Skalickova S, Fernandez C, Ruttkay-Nedecky B, Peng Q, Kizek R. 2018. Nano-selenium and its nanomedicine applications: a critical review. International Journal of Nanomedicine 13: 2107. https://doi. org/10.2147/IJN.S157541

Ibrahim D, Kishawy AT, Khater SI, Hamed Arisha A, Mohammed HA, Abdelaziz AS and Elabbasy MT. 2019. Effect of dietary modulation of selenium form and level on performance, tissue retention, quality of frozen stored meat and gene expression of antioxidant status in ross broiler chickens. Animals 9(6): 342. https://doi.org/10.3390/ani9060342

Ibrahim S E, Alzawqari M H, Eid YZ, Zommara M, Hassan A M and Dawood M A. 2022. Comparing the influences of selenium nanospheres, sodium selenite, and biological selenium on the growth performance, blood biochemistry, and antioxidative capacity of growing turkey pullets. Biological Trace Element Research 200(6): 2915-2922. https://doi.org/10.1007/s12011-021-02894-w

Ighodaro OM and Akinloye OA. 2018. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-PX): Their fundamental role in the entire antioxidant defence grid. Alexandria Journal of Medicine 54(4): 287-293. https://doi.org/10.1016/j. ajme.2017.09.001

Kai O, Nagase H, Ishikawa N, Suzuki M, Kakegawa T and Sato K. 1988. Effects of propylthiouracil (PTU) on the immunological status of the chicken. Development & Comparative Immunology 12(1): 145-156. https://doi.org/10.1016/0145-305X(88)90032-8

Karthiayini K and Philomina PT. 2008. Effect of overcrowding stress on haematological parameters of broiler chicken. Indian Journal of Poultry Science 43(3): 313-16.

Khan MZ, Akter SH, Islam MN, Karim MR, Islam MR and Kon Y. 2008. The effect of selenium and vitamin E on the lymphocytes and immunoglobulin-containing plasma cells in the lymphoid organ and mucosa-associated lymphatic tissues of broiler chickens. Anatomia, Histologia, Embryology 37(1): 52–9. https://doi.org/10.1111/j.1439-0264.2007.00799.x

Latimer GW. 2016. Official methods of analysis of AOAC International. AOAC International, Rockville, MD, USA. Liu J, Wang Z, Li C, Chen Z, Zheng A, Chang W, Liu G and Cai H. 2023. Effects of selenium dietary yeast on growth performance, slaughter performance, antioxidant capacity, and selenium deposition in broiler chickens. Animals 13(24):3830. https://doi.org/10.3390/ani13243830

Madesh M and Balasubramanian KA. 1998. Microtiter plate assay for superoxide dismutase using MTT reduction by superoxide. Indian Journal of Biochemistry & Biophysics 35(3): 184–188.

Mishra B and Jha R. 2019. Oxidative stress in the poultry gut: potential challenges and interventions. Front in Veterinary Science 6: 60. https://doi.org/10.3389/fvets.2019.00060

Mohammadi E, Janmohammadi H, Olyayee M, Helan J A and Kalanaky S. 2020. Nano selenium improves humoral immunity, growth performance and breast-muscle selenium concentration of broiler chickens. Animal Production Science 60(16): 1902-1910. https://doi.org/10.1071/AN19581

Onagbesan O M, Uyanga V A, Oso O, Tona K and Oke O E. 2023. Alleviating heat stress effects in poultry: updates on methods and mechanisms of actions. Frontiers in Veterinary Science 10:1255520. doi: 10.3389/fvets.2023.1255520

Paglia DE. 1967 Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidases. Journal of Laboratory and Clinical Medicine 70: 74-77. https://doi.org/10.5555/uri:pii:0022214367900765

Prabakaran KM, Singh DP, Saxena VK and Narayan R. 2016. Assessment of immune-competence traits among native and cross bred chicken. Indian Journal of Poultry Science 51(1): 15-18. 10.5958/0974-8180.2016.00012.X

Sadeghian S, Kojouri GA and Mohebbi A. 2012. Nanoparticles of selenium as species with stronger physiological effects in sheep in comparison with sodium selenite. Biological Trace Element Research 146(3): 302-308. https://doi.org/10.1007/ s12011-011-9266-8

Sajadifar S, Miranzadeh H and Moazeni M. 2013. Effect of zinc on humoral and cell-mediated immunity of broilers vaccinated against coccidiosis. Iranian Journal of Parasitology 8(3): 474. PMCID: PMC3887251

Selim N A, Radwan N L, Youssef S F, Eldin T S and Elwafa S A. 2015. Effect of inclusion inorganic, organic or nano selenium forms in broiler diets on: 2-Physiological, immunological and toxicity statuses of broiler chicks. International Journal of Poultry Science 14(3): 144. https://doi.org/10.3923/ijps.2015.144.155

Shehata AM, Saadeldin IM, Tukur HA and Habashy WS. 2020. Modulation of heat-shock proteins mediates chicken cell survival against thermal stress. Animals 10(12): 2407. https://doi.org/10.3390/ani10122407

Surai PF, Kochish II, Romanov MN and Griffin DK. 2019. Nutritional modulation of the antioxidant capacities in poultry: the case of vitamin E. Poultry Science 98(9): 4030-4041. https://doi.org/10.3382/ps/pez072

Wang Y. 2009. Differential Effects of Sodium Selenite and Nano-Se on Growth Performance, Tissue Se Distribution, and Glutathione Peroxidase Activity of Avian Broiler. Biological Trace Element Research 128: 184–190. https://doi. org/10.1007/s12011-008-8264-y

Yu H J, Liu J Q, Bock A, Li J, Luo G M and Shen J C. 2005. Engineering glutathione transferase to a novel glutathione peroxidase mimic with high catalytic efficiency: incorporation of selenocysteine into a glutathione-binding scaffold using an auxotrophic expression system. Journal of Biological Chemical 280(12): 11930-11935. https://doi.org/10.1074/jbc. M408574200

Zhang J, Taylor EW, Wan X and Peng D. 2012. Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles. International Journal of Nanomedicine 7: 815. https://doi.org/10.2147/IJN.S28538